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Genetic analysis of transcription factors in dopaminergic neuronal development in Parkinson's disease
Genetic analysis of transcription factors in dopaminergic neuronal development in Parkinson's disease
Background: Genetic variants of dopaminergic transcription factor-encoding genes are suggested to
Hypertension and NAFLD risk: Insights from the NHANES 2017–2018 and Mendelian randomization analyses
Hypertension and NAFLD risk: Insights from the NHANES 2017–2018 and Mendelian randomization analyses
Background: Hypertension and non-alcoholic fatty liver disease (NAFLD) share several pathophysiol
Pancreatic ductal adenocarcinoma chemoresistance: From metabolism reprogramming to novel treatment
Pancreatic ductal adenocarcinoma chemoresistance: From metabolism reprogramming to novel treatment
As pancreatic cancer (PC) is highly malignant, its patients tend to develop metastasis at an early s
Discovery of a normal-tension glaucoma-suspect rhesus macaque with craniocerebral injury: Hints of elevated translaminar cribrosa pressure difference
Discovery of a normal-tension glaucoma-suspect rhesus macaque with craniocerebral injury: Hints of elevated translaminar cribrosa pressure difference
To the Editor: Normal-tension glaucoma (NTG) is a progressive optic neuropathy characterized by irreversible blindness wit...
Comparison of clinical features of nephrotic syndrome after haploidentical and matched donor hematopoietic stem cell transplantation
Comparison of clinical features of nephrotic syndrome after haploidentical and matched donor hematopoietic stem cell transplantation
To the Editor: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the most effective options for hem...
Perinatal outcomes of re-recurrent gestational diabetes mellitus and their prognostic factors: A retrospective cohort study in China
Perinatal outcomes of re-recurrent gestational diabetes mellitus and their prognostic factors: A retrospective cohort study in China
To the Editor: Gestational diabetes mellitus (GDM) is a pathologic condition in which glucose intolerance and insulin resi...
A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis
A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis
Background: Findings on the association of genetic factors and colorectal cancer (CRC) survival a
Pathogens of first-episode pulmonary infection in 141 children with chronic granulomatous disease
Pathogens of first-episode pulmonary infection in 141 children with chronic granulomatous disease
To the Editor: Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency disease characterized by recur...
Current status of cognition and skin care behavior in adolescent patients with acne: A survey in China
Current status of cognition and skin care behavior in adolescent patients with acne: A survey in China
1Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's...
An immunogenic cell death-related signature for prediction of prognosis and response to immunotherapy in breast cancer
An immunogenic cell death-related signature for prediction of prognosis and response to immunotherapy in breast cancer
To the Editor: Tumor immune microenvironment plays a key role in breast cancer development and progression, which determin...
Efficacy of interleukin-17 inhibitors on radiographic progression in psoriatic arthritis: A systematic review and meta-analysis
Efficacy of interleukin-17 inhibitors on radiographic progression in psoriatic arthritis: A systematic review and meta-analysis
To the Editor: Psoriatic arthritis (PsA) is a highly heterogeneous inflammatory arthritis. It occurs in up to 30% of patie...
Endoscopic measurement of lesion size: An unmet clinical need
Endoscopic measurement of lesion size: An unmet clinical need
In recent years, the field of endoscopy has experienced significant technological advancements. These developments have fa...
Implications of glycemic risk index across different levels of glycated hemoglobin (HbA1c) in type 1 diabetes
Implications of glycemic risk index across different levels of glycated hemoglobin (HbA1c) in type 1 diabetes
To the Editor: Glycemic control in individuals with type 1 diabetes (T1D) is challenging and requires multidimensional eva...
Chronic stress as an emerging risk factor for the development and progression of glioma
Chronic stress as an emerging risk factor for the development and progression of glioma
Gliomas tend to have a poor prognosis and are the most common primary malignant tumors of the centra
Artificial intelligence-based analysis of tumor-infiltrating lymphocyte spatial distribution for colorectal cancer prognosis
Artificial intelligence-based analysis of tumor-infiltrating lymphocyte spatial distribution for colorectal cancer prognosis
Background: Artificial intelligence (AI) technology represented by deep learning has made remarka
Tumor-associated telocytes
Tumor-associated telocytes
To the Editor: It has been eighteen years since telocytes (TCs) were first categorized by Popescu et al[1] in 2005. TCs we...
Aryl hydrocarbon receptor: Linking environment to aging process in elderly patients with asthma
Aryl hydrocarbon receptor: Linking environment to aging process in elderly patients with asthma
Aging is a significant risk factor for various diseases, including asthma, and it often leads to poo
Effects of higher femoral tunnels on clinical outcomes, MRI, and second-look findings in double-bundle anterior cruciate ligament reconstruction with a minimal 5-year follow-up
Effects of higher femoral tunnels on clinical outcomes, MRI, and second-look findings in double-bundle anterior cruciate ligament reconstruction with a minimal 5-year follow-up
Background: To perform anatomical anterior cruciate ligament reconstruction (ACLR), tunnels shoul
Considerable impact of major air pollutants on hypertension in Guizhou province, southwest China
Considerable impact of major air pollutants on hypertension in Guizhou province, southwest China
To the Editor: Air pollution can lead to respiratory and cardiovascular diseases (CVDs), and its impact on human health is...
Macroscopic on-site magnifier-based evaluation to estimate visible tissue core cut-off lengths using EUS-FNA with 22-gauge needles
Macroscopic on-site magnifier-based evaluation to estimate visible tissue core cut-off lengths using EUS-FNA with 22-gauge needles
To the Editor: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has replaced other high-risk invasive methods...
Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
Association of cardiopulmonary bypass with acute kidney injury in patients undergoing coronary artery bypass grafting: a retrospective cohort study
To the Editor: Acute kidney injury (AKI) is a frequent complication of both cardiac and major non-cardiac surgeries. Cardi...
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus
Background: Type 2 diabetes mellitus (T2DM) is an independent risk factor for colorectal cancer (
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
Clinical characteristics of flares in patients with rheumatoid arthritis after total hip and total knee arthroplasty
To the Editor: Introduction of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) has been highly eff...
Jak inhibitors in vitiligo: a meta analysis
Jak inhibitors in vitiligo: a meta analysis
To the Editor: Vitiligo is an autoimmune disease characterized by depigmented patches of skin and is challenging to manage...
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
Clinical characteristics and risk factors for new-onset cervicogenic headache following elective craniotomy
To the Editor: New-onset headache within a week after craniotomy is commonly recognized as acute post-craniotomy headache ...
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
Updates in psoriasis diagnosis and treatment status in China: results from the National Psoriasis Center Registry
To the Editor: Psoriasis is a common chronic immune-mediated systemic inflammatory disease[1] characterized by irritating ...
Systemic lupus erythematosus with diffuse alveolar hemorrhage
Systemic lupus erythematosus with diffuse alveolar hemorrhage
To the Editor: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of various auto...
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Increased human neutrophil lipocalin and its clinical relevance in adult-onset Still's disease
Background: Human neutrophil lipocalin (HNL) has been used extensively to differentiate acute bac
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Individualized red-cell transfusion strategy for non-cardiac surgery in adults: a randomized controlled trial
Background: Red-cell transfusion is critical for surgery during the peri-operative period; howeve
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Burden of multiple myeloma in China: an analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019
Background: There is limited data to comprehensively evaluate the epidemiological characteristics
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