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Phytochemical composition of Clinacanthus nutans based on factors of environment, genetics and postharvest processes: A review
Herpes simplex, varicella-zoster lesions, skin rashes, diabetes, snake bites and insect bites have all been treated by usi...
Unveiling the Power of Flavonoids: A Dynamic Exploration of Their Impact on Cancer through Matrix Metalloproteinases Regulation
Cancer is a prominent contributor to mortality rates globally, with its progression and spread being the primary factors u...
Glutaminase - A potential target for cancer treatment
The overexpression of glutaminase is reported to influence cancer growth and metastasis through glutaminolysis. Upregulati...
Protection of Gueichih-Fuling-Wan on cerebral ischemia-induced brain injury in rodents is mediated by trans-cinnamaldehyde via inhibition of neuroinflammation and apoptosis
Background: Stroke is the leading cause of mortality and morbidity worldwide, and an effective therapeutic strategy for th...
Zinc Oxide Nanoparticles-Doped Curcumin-Assisted Recovery of Rheumatoid Arthritis and Antioxidant Status in Experimental Rabbits
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and synovial joint d...
In vitro and in silico evaluation of Andrographis paniculata ethanolic crude extracts on 3 fatty acid synthase expression on breast cancer cells
Background Fatty acid synthase (FASN), a key rate-limiting enzyme in the fatty acid biosynthesis pathway has been identifi...
Comparative analysis of Doxycycline and Ayurvedic herbs to target metastatic breast cancer: An in-silico approach
Background: Metastasis of breast cancer cells to distant sites including lungs, liver, lymph node, brain and many more hav...
A Brief Literature Review of Low-Level Laser Therapy for Treating Amyotrophic Lateral Sclerosis and Confirmation of its Effectiveness
Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a steadily progressive course due to...
Biomedicines in Longevity and Aging The Quest to Resist Biological Decline
Aging is considered part of the natural process of life, however in recent years medical literature has started to show th...
Impact and prevalence of comorbidities and complications on the severity of COVID-19 in association with age, gender, obesity, and pre-existing smoking: A meta-analysis
Background: COVID-19 patients usually present multiple comorbidities and complications associated with severe forms of SAR...
Ethanol leaf extracts of Anogeissus leiocarpus in antioxidants and hepatotoxic effects of Escherichia coli infected Swiss Mice
Introduction: Diseases caused by bacteria can be managed with medicinal plants with rightful dosage that will not affect b...
COMPUTATIONAL ANALYSIS OF DIMER G6PD STRUCTURE TO ELUCIDATE PATHOGENICITY OF G6PD VARIANTS
An inherent genetic enzyme disorder in humans, known as glucose-6-phosphate dehydrogenase (G6PD) deficiency, arises due to...
VKORC1 polymorphisms and complete resistance to Vitamin K antagonists: About two cases.
Complete resistance to vitamin K antagonists is a rare but serious. It can complicate therapeutic management, especially w...
Mutation Patterns of Integrase Gene Affect Antiretroviral Resistance in Various non-B Subtypes of Human Immunodeficiency Virus Type-1 and Their Implications for Patients’ Therapy
Although primary integrase strand transfer inhibitor resistance mutations are currently uncommon, the increasing use of in...
Chemical composition, mineral profile, anti-bacterial, and wound healing properties of snail slime of Helix aspersa Müller
Mucus is a substance made by snails that serves a variety of purposes and is increasingly employed in the medical and cosm...
Efficacy of HMJ-38, a new quinazolinone analogue, against the gemcitabine-resistant MIA-PaCa-2 pancreatic cancer cells
Gemcitabine is frequently utilized to treat pancreatic cancer. The purpose of our study was to create a gemcitabine-resist...
Hematological Biomarkers of Troponin, Neutrophil-to-Lymphocyte Ratio, and Monocyte-toLymphocyte Ratio Serve as Effective Predictive Indicators of High-Risk Mortality in Acute
Background: Assessing high-risk mortality in acute coronary syndrome (ACS) patients, encompassing ST-Elevation Myocardial ...
Celastrol restricts experimental periodontitis related alveolar bone loss by suppressing inflammatory cytokine response
Introduction: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting st...
Continuous Intrathecal Saline Infusion for Treating Refractory Spontaneous Intracranial Hypotension: A Case Report
Spontaneous intracranial hypotension (SIH) is a poorly understood condition that presents with a wide variety of symptoms,...
Endometrial Fluid Biomarkers And Their Potential As Predictors Of Successful Embryo Implantation
Background: Embryo implantation is a complex biological process which requires synchronized dialogue between the receptive...
Age-Specific Percentile-based Prostate-Specific Antigen Cutoff Values Predict the Risk of Prostate Cancer: a single hospital observation
Background Testing for prostate-specific antigen (PSA) is often recommended for men with a potential risk of prostate canc...
Evaluation of antibacterial efficacy of Lawsonia inermis Linn (henna) on periodontal pathogens using agar well diffusion and broth microdilution methods: an in-vitro study
Background: Although widely explored in medicine, limited evidence exists in the literature regarding the efficacy of Laws...
Evaluation of SARS-CoV-2 infection risks after primary vaccination with BNT162b2, BBIBP-CorV, or ChAdOx1-nCOV-19 and after homologous and heterologous booster vaccinations with these vaccines and evaluation of SARS-CoV-2 reinfection profiles
Background: The emergence of SARS-CoV-2 variants has significantly increased the number of cases of COVID-19 among vaccina...
Hipoxia modulates the secretion of growth factors in of human umbilical cord-derived mesenchymal stem cells
Background: Mesenchymal stem cell (MSC) has great potential as therapies due its ability to regenerate tissue damage and p...
Combination treatment of pembrolizumab with DC-CIK cell therapy for Advanced hepatocellular carcinoma: a case report
Background: Recently, immunotherapy has emerged as a promising method for advanced HCC treatment. There are several clinic...
Precision Medicine Advancements in Glioblastoma: A Systematic Review
Background. Glioblastoma multiforme, commonly known as GBM or glioblastoma is a grade IV astrocytoma. Brain tumors are dif...
Metformin induces autophagy of cisplatin-resistant human gastric cancer cells in addition to apoptosis
Metformin has been used to treat cases of type 2 diabetes mellitus, and mounting studies have shown that metformin can act...
Effects of Anti-Retroviral Therapy on Baseline Serum Interleukin-18 levels in HIV-I Infected Patients Relative to Viral Suppression and CD4+ Gain: a prospective pilot study
Background: In HIV infection, dysregulation of cytokines, including interleukin 18 (IL-18), has been linked to poor clinic...
Red cell distribution width, neutrophil lymphocyte ratio and interleukin 10 are good prognostic markers in multiple myeloma
Multiple myeloma (MM) is still an incurable disease so we need to continue developing new diagnostic and prognostic option...
Toxicological Evaluation of a Polyherbal Formulation on Testicular Function and Gonadal Histomorphology in Exposed Wistar Rats
Introduction: Dr Iguedo Goko Cleanser® is a herbal formulation (HF) widely marketed in southern Nigeria and purported to b...
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