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'Maybe were not past the traditional gender roles then! Exploring less than full-time training among men in Scotland: a qualitative study
'Maybe were not past the traditional gender roles then! Exploring less than full-time training among men in Scotland: a qualitative study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study is novel in exploring less than full-time training from a male perspectiv...
Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)
Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)
IntroductionSickle cell disease (SCD) is the most frequent autosomal recessive disease, resulting in the production of sic...
Factors influencing postoperative urinary retention after radical hysterectomy for cervical cancer: development and validation of a predictive model in a prospective cohort study in Southwest China
Factors influencing postoperative urinary retention after radical hysterectomy for cervical cancer: development and validation of a predictive model in a prospective cohort study in Southwest China
IntroductionCervical cancer stands as the fourth leading cause of cancer among women globally, with around 604 000 new cas...
Prevalence of physical inactivity and associated factors among adults in Eastern African countries: a systematic review and meta-analysis protocol
Prevalence of physical inactivity and associated factors among adults in Eastern African countries: a systematic review and meta-analysis protocol
IntroductionRegular physical activity is essential for preventing and managing non-communicable diseases (NCDs), such as c...
iDiabetes platform--enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in Tayside, Scotland
iDiabetes platform--enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in Tayside, Scotland
BackgroundDiabetes is increasing in prevalence worldwide, giving rise to a spectrum of associated comorbidities including ...
Health Navigator intervention to address the unmet social needs of populations living with cancer attending outpatient treatment at a major metropolitan hospital in Australia: protocol for a mixed-methods feasibility trial
Health Navigator intervention to address the unmet social needs of populations living with cancer attending outpatient treatment at a major metropolitan hospital in Australia: protocol for a mixed-methods feasibility trial
IntroductionSocial determinants of health (SDoH; eg, housing, neighbourhood and physical environment, safety) are key driv...
Rapid antibiotic susceptibility testing for urinary tract infections in secondary care in England: a cost-effectiveness analysis
Rapid antibiotic susceptibility testing for urinary tract infections in secondary care in England: a cost-effectiveness analysis
Strengths and limitations of this studyA novel mathematical model is used to quantify both the costs and health benefits o...
Predictors of upper limb motor recovery in stroke survivors: a pre-post test study design
Predictors of upper limb motor recovery in stroke survivors: a pre-post test study design
STRENGTHS AND LIMITATIONS OF THIS STUDYThe pre–post study design allowed for the evaluation of changes in motor function o...
Exploring the use of ChatGPT-4o in enhancing career development counseling for medical students: a study protocol
Exploring the use of ChatGPT-4o in enhancing career development counseling for medical students: a study protocol
BackgroundThe emergence of pre-trained generative transformers, notably ChatGPT, has profoundly influenced medical educati...
Does hospital strategic alliance affect the paediatric service capacity of local hospitals? A difference-in-differences econometric analysis
Does hospital strategic alliance affect the paediatric service capacity of local hospitals? A difference-in-differences econometric analysis
STRENGTHS AND LIMITATIONS OF THIS STUDYWe evaluated the impact of this reform using a difference-in-differences analysis w...
Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis
Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis
STRENGTHS AND LIMITATIONS OF THIS STUDYThis was the first study to pool the results of numerous primary studies.The includ...
Magnitude and associated factors of delayed treatment seeking among patients with malaria in Andabet district, Northwest Ethiopia, 2022: a multicentre institution-based cross-sectional study
Magnitude and associated factors of delayed treatment seeking among patients with malaria in Andabet district, Northwest Ethiopia, 2022: a multicentre institution-based cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study was conducted in multicentre (six health centres), which increases gener...
Context, mechanisms and community engagement in implementation strategies: a systematic review protocol of implementation strategies designed using implementation mapping
Context, mechanisms and community engagement in implementation strategies: a systematic review protocol of implementation strategies designed using implementation mapping
IntroductionThe timely and effective translation of evidence-based interventions (EBI) into practice is crucial for advanc...
Exploring adults recollections of growing up with childhood motor difficulties: a qualitative study using systematic text condensation
Exploring adults recollections of growing up with childhood motor difficulties: a qualitative study using systematic text condensation
IntroductionDevelopmental coordination disorder (DCD) is a neurodevelopmental disorder that adversely affects the ability ...
Evidence-informed, experience-based co-design: a novel framework integrating research evidence and lived experience in priority-setting and co-design of health services
Evidence-informed, experience-based co-design: a novel framework integrating research evidence and lived experience in priority-setting and co-design of health services
BackgroundInvolving consumers and clinicians in the planning, design and implementation of services results in the end-pro...
Quantitative analysis of nortriptylines analgesic properties: a comparative systematic review and meta-analysis
Quantitative analysis of nortriptylines analgesic properties: a comparative systematic review and meta-analysis
IntroductionPain is a multifaceted experience that can be triggered by a variety of painful stimuli. It is a response that...
Impact of the diagnostic label for a low-risk prostate lesion: protocol for two online factorial randomised experiments
Impact of the diagnostic label for a low-risk prostate lesion: protocol for two online factorial randomised experiments
IntroductionOver the past decades, there have been large increases in the diagnosis of prostate cancer with the widespread...
Protocol for a randomised trial of a self-directed digital pain management intervention (Empowered Relief) tailored to adults with chronic pain and prescription opioid misuse/disorder: the MOBILE Relief study
Protocol for a randomised trial of a self-directed digital pain management intervention (Empowered Relief) tailored to adults with chronic pain and prescription opioid misuse/disorder: the MOBILE Relief study
IntroductionGlobally, rates of opioid overdose have increased in the last decade, with the largest increases observed in N...
Rapid Assay Diagnostic for Acute Stroke Recognition (RADAR): study protocol for a diagnostic accuracy study
Rapid Assay Diagnostic for Acute Stroke Recognition (RADAR): study protocol for a diagnostic accuracy study
IntroductionStroke caused by cerebral ischaemia (85%) or haemorrhage (15%) affects around 13.7 million people across the w...
Antibiotic use in public hospitals in Vietnam between 2018 and 2022: a retrospective study
Antibiotic use in public hospitals in Vietnam between 2018 and 2022: a retrospective study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study represents the largest multicentre assessment of antibiotic use over 5 y...
Specialist intellectual disability liaison nurses in general hospitals in England: cohort study using a large mortality dataset
Specialist intellectual disability liaison nurses in general hospitals in England: cohort study using a large mortality dataset
Summary of key findingsSpecialist intellectual disability liaison nurses have been recommended to work across general hosp...
Reduction of head and neck cancer risk following smoking cessation: a systematic review and meta-analysis
Reduction of head and neck cancer risk following smoking cessation: a systematic review and meta-analysis
STRENGTHS AND LIMITATIONS OF THIS STUDYLarge number of studies and participants provide high statistical power.Effect of d...
Study protocol: diagnostic accuracy study comparing Cy-Tb and STANDARD F TB-Feron FIA tests for tuberculosis infection diagnosis in Vietnam
Study protocol: diagnostic accuracy study comparing Cy-Tb and STANDARD F TB-Feron FIA tests for tuberculosis infection diagnosis in Vietnam
BackgroundTuberculosis (TB) is an infectious disease that is a leading cause of morbidity and mortality globally. There we...
Recruitment, retention and reporting of variables related to ethnic diversity in randomised controlled trials: an umbrella review
Recruitment, retention and reporting of variables related to ethnic diversity in randomised controlled trials: an umbrella review
IntroductionRandomised controlled trials (hereafter, trials) are considered the gold standard method to assess the effecti...
Analysis of the current situation and demand for perinatal education in pregnant women in general grade A tertiary hospitals in China: a cross-sectional survey
Analysis of the current situation and demand for perinatal education in pregnant women in general grade A tertiary hospitals in China: a cross-sectional survey
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study used a cross-sectional survey to accurately capture the perinatal educati...
Lactoferrin and lysozyme to promote nutritional, clinical and enteric recovery: a protocol for a factorial, blinded, placebo-controlled randomised trial among children with diarrhoea and malnutrition (the Boresha Afya trial)
Lactoferrin and lysozyme to promote nutritional, clinical and enteric recovery: a protocol for a factorial, blinded, placebo-controlled randomised trial among children with diarrhoea and malnutrition (the Boresha Afya trial)
BackgroundFive hundred thousand children die each year from diarrhoea, mostly in low-income and middle-income countries (L...
Perioperative non-pharmaceutical therapies for insomnia in cancer survivors: a systematic review and network meta-analysis protocol
Perioperative non-pharmaceutical therapies for insomnia in cancer survivors: a systematic review and network meta-analysis protocol
IntroductionInsomnia is a prevalent issue among cancer survivors, with studies revealing that nearly 60% of them experienc...
Registry-based cohort study comparing percentages of patients reaching PASS for knee function outcomes after revision ACLR compared to primary ACLR
Registry-based cohort study comparing percentages of patients reaching PASS for knee function outcomes after revision ACLR compared to primary ACLR
Strengths and limitations of this studyThe large sample size allows assessment of outcomes following anterior cruciate lig...
Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study
Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study
IntroductionAround a third of twin pregnancies share a placenta (monochorionic (MC) twins);1 this poses unique difficultie...
Animations to communicate public health prevention messages: a realist review protocol
Animations to communicate public health prevention messages: a realist review protocol
The individual, societal and economic costs of preventable ill health and disease are significant, accounting for between ...
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