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Novel Therapeutic Target for ALI/ARDS: Forkhead Box Transcription Factors
Novel Therapeutic Target for ALI/ARDS: Forkhead Box Transcription Factors
ALI/ARDS can be a pulmonary manifestation of a systemic inflammatory response or a result of overexpression of the body...
Longitudinal Cough Frequency Monitoring in Persistent Coughers: Daily Variability and Predictability
Longitudinal Cough Frequency Monitoring in Persistent Coughers: Daily Variability and Predictability
We determined the cough counts and their variability in subjects with persistent cough for 30 days. The Hyfe coug...
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis
There has been growing interest in using artificial intelligence/deep learning (DL) to help diagnose prevalent diseases ea...
Correction to: Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
Correction to: Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
In this article, the author noticed that the Title and some values in the Results section, Figures 1, 2, 4 caption and Fig...
ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension
ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) represents an important clinical indication for lung transplant (LTx) in...
Utility of the 52-Gene Risk Score to Identify Patients with Idiopathic Pulmonary Fibrosis at Greater Risk of Mortality in the Era of Antifibrotic Therapy
Utility of the 52-Gene Risk Score to Identify Patients with Idiopathic Pulmonary Fibrosis at Greater Risk of Mortality in the Era of Antifibrotic Therapy
We investigated whether a 52-gene signature was associated with transplant-free survival and other clinically meaningful o...
Pseudomonas aeruginosa Infection and Inflammation in Cystic Fibrosis: A Pilot Study With Lung Explants and a Novel Histopathology Scoring System
Pseudomonas aeruginosa is the predominant bacterial pathogen colonizing the cystic fibrosis (CF) lung. Mixed populations o...
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model
Over 550 loci have been associated with human pulmonary function in genome-wide association studies (GWAS); however, the c...
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease
The pulmonary lymphatic system has emerged as a critical regulator of lung homeostasis and a key contributor to the pathog...
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
Lung transplantation (LTx) is a potential intervention for end-stage COVID-19 lung disease. Current literature is sparse r...
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis
In sarcoidosis granulomas, monocyte-derived macrophages are activated by pro-inflammatory cytokines including TNF and IL-6...
The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies
The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies
Azithromycin is an effective treatment for various respiratory conditions but its effect on cough is poorly understood. We...
Establishment and Validation of a Risk Prediction Model for Non-Invasive Ventilation Failure After Birth in Premature Infants with Gestational Age < 32 Weeks
Establishment and Validation of a Risk Prediction Model for Non-Invasive Ventilation Failure After Birth in Premature Infants with Gestational Age < 32 Weeks
This study was performed to construct and validate a risk prediction model for non-invasive ventilation (NIV) failure afte...
TRIM13 Reduces Damage to Alveolar Epithelial Cells in COPD by Inhibiting Endoplasmic Reticulum Stress-Induced ER-Phagy
TRIM13 Reduces Damage to Alveolar Epithelial Cells in COPD by Inhibiting Endoplasmic Reticulum Stress-Induced ER-Phagy
Tripartite motif-containing protein 13 (TRIM13) directly or indirectly participates in autophagy and apoptosis. However, i...
Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study
Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study
Lymphangioleiomyomatosis (LAM) is a rare (twenty-one per million female inhabitants) neoplastic cystic lung disease that i...
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study
Author notesQiong Wen and Li Li are co-corresponding authors.Authors and AffiliationsDepartment of Oncology, The First Aff...
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
Pulmonary fibrosis is a characteristic of various interstitial lung diseases (ILDs) with differing etiologies. Clinical tr...
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Next Generation Sequencing Yields
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Next Generation Sequencing Yields
The use of endobronchial ultrasound (EBUS) is standard practice for lung cancer diagnosis and staging. Next generation seq...
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
As a biomarker of alveolar-capillary basement membrane injury, Krebs von den Lungen-6 (KL-6) is involved in the occurrence...
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinic...
Emerging Roles of Galectin-3 in Pulmonary Diseases
Emerging Roles of Galectin-3 in Pulmonary Diseases
Galectin-3 is a multifunctional protein that is involved in various physiological and pathological events. Emerging eviden...
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis
Skin pigmentation influences peripheral oxygen saturation (SpO2) compared to arterial saturation of oxygen (SaO2). Occult ...
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
Fibrotic interstitial lung disease is often identified late due to non-specific symptoms, inadequate access to specialist ...
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey
Chronic cough (persisting for ≥ 8&nbsp;weeks) is a common disorder that includes refractory chronic ...
Ultrathin Bronchoscopy Without Virtual Navigation for Diagnosis of Peripheral Lung Lesions
Ultrathin Bronchoscopy Without Virtual Navigation for Diagnosis of Peripheral Lung Lesions
The increasing incidence of encountering lung nodules necessitates an ongoing search for improved diagnostic procedures. V...
Type 2 Biomarkers and Their Clinical Implications in Bronchiectasis: A Prospective Cohort Study
Type 2 Biomarkers and Their Clinical Implications in Bronchiectasis: A Prospective Cohort Study
Bronchiectasis is predominantly marked by neutrophilic inflammation. The relevance of type 2 biomarkers in disease severit...
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis
Treatment of allergic bronchopulmonary aspergillosis (ABPA) is challenging. Biological therapies have been reported as adj...
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease
Transbronchial lung cryobiopsy (TBLC) is increasingly used to diagnose interstitial lung disease (ILD). The 1.1-mm cryopro...
Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study
Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study
Critically ill patients with chronic obstructive pulmonary disease (COPD) face significant mortality after hospital discha...
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic (2597/2600)
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic (2597/2600)
Lung transplantation (LTx) is a potential intervention for end-stage COVID-19 lung disease. Current literature is sparse r...
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