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Inequalities in care and the burden of wheeze and asthma in young children from diverse socioeconomic and ethnic backgrounds
Inequalities in care and the burden of wheeze and asthma in young children from diverse socioeconomic and ethnic backgrounds
Worldwide inequalities in care significantly impact respiratory health outcomes.1 2 Despite this, there are few studies ex...
Non-cigarette tobacco products, aryl-hydrocarbon receptor repressor gene methylation and smoking-related health outcomes
Non-cigarette tobacco products, aryl-hydrocarbon receptor repressor gene methylation and smoking-related health outcomes
Study populationThe National Heart, Lung and Blood Institute (NHLBI) Pooled Cohorts Study12 harmonised data from four pros...
Refractory granulomatous Pneumocystis jirovecii pneumonia masquerading as malignancy
Refractory granulomatous Pneumocystis jirovecii pneumonia masquerading as malignancy
An elderly female, lifelong non-smoker, with rheumatoid arthritis treated with methotrexate and prednisone for 10 years wa...
Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study
Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study
IntroductionWheezing illnesses in young children are extremely common, with up to half experiencing an episode by the age ...
Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis
Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis
A 47-year-old male presented with chronic cough, which has worsened over the last 5–6 months. Dyspnoea, fever and signific...
Editorial of utility of the Global Lung Function Initiative (GLI) for ILD
Editorial of utility of the Global Lung Function Initiative (GLI) for ILD
Interstitial lung disease (ILD) is a heterogeneous parenchymal disorder.1 2 Patients with ILD often present with non-speci...
Predicting the risk of pulmonary deterioration in sarcoidosis
Predicting the risk of pulmonary deterioration in sarcoidosis
In sarcoidosis, any organ may be affected, and the majority of cases have pulmonary involvement. The disease course in pul...
Association of positive airway pressure termination with mortality and non-fatal cardiovascular events in patients with obstructive sleep apnoea
Association of positive airway pressure termination with mortality and non-fatal cardiovascular events in patients with obstructive sleep apnoea
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Impact of TAS2R38 polymorphisms on nasal nitric oxide and Pseudomonas infections in primary ciliary dyskinesia: relation to genotype
Impact of TAS2R38 polymorphisms on nasal nitric oxide and Pseudomonas infections in primary ciliary dyskinesia: relation to genotype
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Unusual cause of trepopnea
Unusual cause of trepopnea
A 19-year-old female presented with a 6-month history of progressive shortness of breath. She reported a new onset of palp...
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia
IntroductionIn spite of decades-long efforts, therapeutics capable of ameliorating disease pathophysiology and improving p...
Perivascular epithelioid cell neoplasm of lung
Perivascular epithelioid cell neoplasm of lung
A 73-year-old woman was found to have a pulmonary mass on a CT scan of the chest 10 years ago, but did not receive any tre...
To progress or not to progress: new insights into the evolution of pleuropulmonary blastomas come from studying lung cysts in adolescents and adults with DICER1-related tumour predisposition
To progress or not to progress: new insights into the evolution of pleuropulmonary blastomas come from studying lung cysts in adolescents and adults with DICER1-related tumour predisposition
Almost all cases of pleuropulmonary blastoma (PPB), the most common lung malignancy in childhood, are related to biallelic...
Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing
Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing
IntroductionSurgical resection remains the recommended treatment for early-stage non-small cell lung cancer (NSCLC) and so...
Unilateral pleural effusion with pulmonary hypertension in sarcoidosis: do not forget the pulmonary veins!
Unilateral pleural effusion with pulmonary hypertension in sarcoidosis: do not forget the pulmonary veins!
A 64-year-old woman presented with exertional dyspnoea and ankle oedema. She had lung biopsy-confirmed sarcoidosis 6 years...
Incidence, prevalence and mortality of idiopathic pulmonary fibrosis in England from 2008 to 2018: a cohort study
Incidence, prevalence and mortality of idiopathic pulmonary fibrosis in England from 2008 to 2018: a cohort study
AbstractBackground Owing to discrepancies in methodologies and how idiopathic pulmonary fibrosis (IPF) is diagnosed it is ...
Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders
Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders
IntroductionRespiratory disorders encompass a range of acute and chronic disorders caused by disordered phenotypes at the ...
New path for understanding mucociliary clearance
New path for understanding mucociliary clearance
The mucociliary clearance (MC) system is a vital host defence in the lungs and upper airways. Airway mucus traps inhaled b...
Heteroresistance in tuberculosis: are we missing drug-resistant bacteria hiding in plain sight?
Heteroresistance in tuberculosis: are we missing drug-resistant bacteria hiding in plain sight?
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) remains the dominant cause of death from a bacterial infectio...
Toxic metals and lung health: silent poisons?
Toxic metals and lung health: silent poisons?
Lady Astor: ‘Sir, if you were my husband , I would put arsenic in your tea!’ Churchill: ‘If I were your husband , I woul...
Ablation for lung cancer: hot or cold intervention
Ablation for lung cancer: hot or cold intervention
Over the past two decades, there has been a notable shift in the natural history and epidemiology of lung cancer. Previous...
Epidemiology of idiopathic pulmonary fibrosis: opportunities and hurdles for population-level studies of rare disease
Epidemiology of idiopathic pulmonary fibrosis: opportunities and hurdles for population-level studies of rare disease
Idiopathic pulmonary fibrosis (IPF) is a rare condition for which reliable disease trends over time can be difficult to ob...
Comprehensive analysis of environmental exposure to hazardous trace elements and lung function: a national cross-sectional study
Comprehensive analysis of environmental exposure to hazardous trace elements and lung function: a national cross-sectional study
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Mucus clears from the trachea in a helix: a new twist to understanding airway diseases
Mucus clears from the trachea in a helix: a new twist to understanding airway diseases
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Strengthening the evidence base to support stronger regulation of social media based advertising of e-cigarette products to youth
Strengthening the evidence base to support stronger regulation of social media based advertising of e-cigarette products to youth
Despite the early promise of e-cigarettes as a potential smoking cessation tool, the actual uptake of these products has b...
Actinomycosis mimicking metastatic lung malignancy
Actinomycosis mimicking metastatic lung malignancy
A 66-year-old Nepalese man with a medical history of hypertension presented with a 4-month history of an intermittently pr...
Definition of diaphragmatic sleep disordered breathing and clinical meaning in Duchenne muscular dystrophy
Definition of diaphragmatic sleep disordered breathing and clinical meaning in Duchenne muscular dystrophy
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Prevalence of lung cysts in adolescents and adults with a germline DICER1 pathogenic/likely pathogenic variant: a report from the National Institutes of Health and International Pleuropulmonary Blastoma/DICER1 Registry
Prevalence of lung cysts in adolescents and adults with a germline DICER1 pathogenic/likely pathogenic variant: a report from the National Institutes of Health and International Pleuropulmonary Blastoma/DICER1 Registry
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Challenging the gold standard: the limitations of molecular assays for detection of Mycobacterium tuberculosis heteroresistance
Challenging the gold standard: the limitations of molecular assays for detection of Mycobacterium tuberculosis heteroresistance
WHAT IS ALREADY KNOWN ON THIS TOPICAntibiotic regimens used in Mycobacterium tuberculosis (M. tb) treatment have significa...
Association of time spent on social media with youth cigarette smoking and e-cigarette use in the UK: a national longitudinal study
Association of time spent on social media with youth cigarette smoking and e-cigarette use in the UK: a national longitudinal study
WHAT IS ALREADY KNOWN ON THIS TOPICThere is substantial use of social media among children and young people, which has had...
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