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Inhaled corticosteroids may be useful in bronchiectasis with peripheral blood eosinophilia
Inhaled corticosteroids may be useful in bronchiectasis with peripheral blood eosinophilia
Bronchiectasis, a clinical syndrome of recurrent cough and sputum production, can be diagnosed when high-resolution CT (HR...
You cant always get what you want: evidence for exacerbation reduction with domiciliary oxygen therapy
You cant always get what you want: evidence for exacerbation reduction with domiciliary oxygen therapy
On a rather cold summer afternoon 45 years ago, I found myself, a humble research fellow, in a committee room in the Unive...
Short-term efficacy of inhaled short-acting beta-2-agonists for acute wheeze/asthma symptoms in preschool-aged children: a systematic review and meta-analysis
Short-term efficacy of inhaled short-acting beta-2-agonists for acute wheeze/asthma symptoms in preschool-aged children: a systematic review and meta-analysis
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Use of inhaled corticosteroids in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
Use of inhaled corticosteroids in bronchiectasis: data from the European Bronchiectasis Registry (EMBARC)
IntroductionInhaled corticosteroids (ICS) are powerful anti-inflammatory and immunosuppressive drugs that inhibit the expr...
Clinical presentation and prognosis of acute symptomatic pulmonary embolism in patients with concomitant upper-extremity versus lower-extremity deep vein thrombosis
Clinical presentation and prognosis of acute symptomatic pulmonary embolism in patients with concomitant upper-extremity versus lower-extremity deep vein thrombosis
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Effects of long-term oxygen therapy on acute exacerbation and hospital burden: the national DISCOVERY study
Effects of long-term oxygen therapy on acute exacerbation and hospital burden: the national DISCOVERY study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSUsing the Swedish nationwide, population-based DISCOVERY cohort, LT...
Association between asthma and type 2 diabetes in a Swedish adult population: a register-based cross-sectional study
Association between asthma and type 2 diabetes in a Swedish adult population: a register-based cross-sectional study
IntroductionAsthma and type 2 diabetes are two complex and prevalent diseases, each constituting a significant public heal...
Effect of time of day and seasonal variation on bronchodilator responsiveness: the SPIRO-TIMETRY study
Effect of time of day and seasonal variation on bronchodilator responsiveness: the SPIRO-TIMETRY study
IntroductionA key diagnostic criterion of asthma is bronchodilator responsiveness, traditionally defined as an improvement...
Adult asthma hospitalisations decreased markedly in Finland and Sweden between 2006 and 2022
Adult asthma hospitalisations decreased markedly in Finland and Sweden between 2006 and 2022
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Occlusive primary endobronchial amyloid tumour: a rare case
Occlusive primary endobronchial amyloid tumour: a rare case
A female aged 69 year never smoker presented with 4 months of non-resolving productive cough and shortness of breath on ex...
Invasive angiolipoma of the mediastinum and lung
Invasive angiolipoma of the mediastinum and lung
A 12-year-old boy presented with a 1 month history of cough and exertional dyspnoea. Physical examination revealed a heart...
Inequalities in care and the burden of wheeze and asthma in young children from diverse socioeconomic and ethnic backgrounds
Inequalities in care and the burden of wheeze and asthma in young children from diverse socioeconomic and ethnic backgrounds
Worldwide inequalities in care significantly impact respiratory health outcomes.1 2 Despite this, there are few studies ex...
Non-cigarette tobacco products, aryl-hydrocarbon receptor repressor gene methylation and smoking-related health outcomes
Non-cigarette tobacco products, aryl-hydrocarbon receptor repressor gene methylation and smoking-related health outcomes
Study populationThe National Heart, Lung and Blood Institute (NHLBI) Pooled Cohorts Study12 harmonised data from four pros...
Refractory granulomatous Pneumocystis jirovecii pneumonia masquerading as malignancy
Refractory granulomatous Pneumocystis jirovecii pneumonia masquerading as malignancy
An elderly female, lifelong non-smoker, with rheumatoid arthritis treated with methotrexate and prednisone for 10 years wa...
Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study
Association between socioeconomic deprivation, ethnicity and health outcomes in preschool children with recurrent wheeze in England: a retrospective cohort study
IntroductionWheezing illnesses in young children are extremely common, with up to half experiencing an episode by the age ...
Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis
Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis
A 47-year-old male presented with chronic cough, which has worsened over the last 5–6 months. Dyspnoea, fever and signific...
Editorial of utility of the Global Lung Function Initiative (GLI) for ILD
Editorial of utility of the Global Lung Function Initiative (GLI) for ILD
Interstitial lung disease (ILD) is a heterogeneous parenchymal disorder.1 2 Patients with ILD often present with non-speci...
Predicting the risk of pulmonary deterioration in sarcoidosis
Predicting the risk of pulmonary deterioration in sarcoidosis
In sarcoidosis, any organ may be affected, and the majority of cases have pulmonary involvement. The disease course in pul...
Association of positive airway pressure termination with mortality and non-fatal cardiovascular events in patients with obstructive sleep apnoea
Association of positive airway pressure termination with mortality and non-fatal cardiovascular events in patients with obstructive sleep apnoea
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Impact of TAS2R38 polymorphisms on nasal nitric oxide and Pseudomonas infections in primary ciliary dyskinesia: relation to genotype
Impact of TAS2R38 polymorphisms on nasal nitric oxide and Pseudomonas infections in primary ciliary dyskinesia: relation to genotype
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Unusual cause of trepopnea
Unusual cause of trepopnea
A 19-year-old female presented with a 6-month history of progressive shortness of breath. She reported a new onset of palp...
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia
IntroductionIn spite of decades-long efforts, therapeutics capable of ameliorating disease pathophysiology and improving p...
Perivascular epithelioid cell neoplasm of lung
Perivascular epithelioid cell neoplasm of lung
A 73-year-old woman was found to have a pulmonary mass on a CT scan of the chest 10 years ago, but did not receive any tre...
To progress or not to progress: new insights into the evolution of pleuropulmonary blastomas come from studying lung cysts in adolescents and adults with DICER1-related tumour predisposition
To progress or not to progress: new insights into the evolution of pleuropulmonary blastomas come from studying lung cysts in adolescents and adults with DICER1-related tumour predisposition
Almost all cases of pleuropulmonary blastoma (PPB), the most common lung malignancy in childhood, are related to biallelic...
Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing
Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing
IntroductionSurgical resection remains the recommended treatment for early-stage non-small cell lung cancer (NSCLC) and so...
Unilateral pleural effusion with pulmonary hypertension in sarcoidosis: do not forget the pulmonary veins!
Unilateral pleural effusion with pulmonary hypertension in sarcoidosis: do not forget the pulmonary veins!
A 64-year-old woman presented with exertional dyspnoea and ankle oedema. She had lung biopsy-confirmed sarcoidosis 6 years...
Incidence, prevalence and mortality of idiopathic pulmonary fibrosis in England from 2008 to 2018: a cohort study
Incidence, prevalence and mortality of idiopathic pulmonary fibrosis in England from 2008 to 2018: a cohort study
AbstractBackground Owing to discrepancies in methodologies and how idiopathic pulmonary fibrosis (IPF) is diagnosed it is ...
Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders
Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders
IntroductionRespiratory disorders encompass a range of acute and chronic disorders caused by disordered phenotypes at the ...
New path for understanding mucociliary clearance
New path for understanding mucociliary clearance
The mucociliary clearance (MC) system is a vital host defence in the lungs and upper airways. Airway mucus traps inhaled b...
Heteroresistance in tuberculosis: are we missing drug-resistant bacteria hiding in plain sight?
Heteroresistance in tuberculosis: are we missing drug-resistant bacteria hiding in plain sight?
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) remains the dominant cause of death from a bacterial infectio...
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