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Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma
Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionAsthma is a global ...
Massive thymoma mimicking a pleural mass
Massive thymoma mimicking a pleural mass
A 37-year-old man presented with months of weight loss, dysphagia and fatigue. He was an infrequent smoker, had no medical...
Not all wheeze is asthma
Not all wheeze is asthma
A 41-year-old man previously diagnosed with asthma presented with an influenza-like illness and breathlessness. He was tre...
Protective effect of height on long-term survival of resectable lung cancer: a new feature of the lung cancer paradox
Protective effect of height on long-term survival of resectable lung cancer: a new feature of the lung cancer paradox
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Diagnosis of cystic lung diseases: a position statement from the UK Cystic Lung Disease Rare Disease Collaborative Network
Diagnosis of cystic lung diseases: a position statement from the UK Cystic Lung Disease Rare Disease Collaborative Network
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Decoding pulmonary nodules: can machine learning enhance malignancy risk stratification?
Decoding pulmonary nodules: can machine learning enhance malignancy risk stratification?
Randomised controlled trials, with the National Lung Screening Trial and Dutch-Belgian NELSON trial being the two largest,...
Use of inhaled treprostinil in patients with interstitial lung disease and pulmonary hypertension: to boldly go where no other pulmonary vasodilator has gone before?
Use of inhaled treprostinil in patients with interstitial lung disease and pulmonary hypertension: to boldly go where no other pulmonary vasodilator has gone before?
Pulmonary hypertension (PH) is a feared complication in patients with any chronic lung disease,1 but those with lung fibro...
Blood eosinophils take centre stage in predicting the response to sublingual immunotherapy (SLIT): a familiar twist
Blood eosinophils take centre stage in predicting the response to sublingual immunotherapy (SLIT): a familiar twist
Sublingual immunotherapy (SLIT) represents a safer, more comfortable and more convenient allergen immunotherapy than its s...
Survival analysis from the INCREASE study in PH-ILD: evaluating the impact of treatment crossover on overall mortality
Survival analysis from the INCREASE study in PH-ILD: evaluating the impact of treatment crossover on overall mortality
WHAT IS ALREADY KNOWN ON THIS TOPICIn the INCREASE trial, inhaled treprostinil was evaluated in patients with pulmonary hy...
Post-pandemic tuberculosis incidence: potential success of active case finding?
Post-pandemic tuberculosis incidence: potential success of active case finding?
Until 2020, tuberculosis (TB) was annually the number one infectious killer disease globally. When the COVID-19 pandemic s...
Well-differentiated papillary mesothelial tumour: a rare finding on the pleura
Well-differentiated papillary mesothelial tumour: a rare finding on the pleura
A 72-year-old woman presented to the emergency department with a history of non-specific intermittent abdominal pain. The ...
Type-2 inflammation: a key treatable trait associated with lung function decline in chronic airways disease
Type-2 inflammation: a key treatable trait associated with lung function decline in chronic airways disease
The chronic airways diseases, asthma and Chronic Obstructive Pulmonary Disease (COPD), are highly prevalent conditions cau...
Twenty-year-old patient with polyarthritis since childhood showing cysts and ground glass attenuation on HRCT
Twenty-year-old patient with polyarthritis since childhood showing cysts and ground glass attenuation on HRCT
We present a case of a 20-year-old woman reporting polyarthritis, muscle weakness, dyspnoea and multiple intensive care un...
Type-2 inflammation and lung function decline in chronic airway disease in the general population
Type-2 inflammation and lung function decline in chronic airway disease in the general population
WHAT IS ALREADY KNOWN ON THIS TOPICType-2 inflammation is increasingly recognised as an important clinical feature in pati...
Low-load blood flow restriction strength training in patients with COPD: a randomised single-blind pilot study
Low-load blood flow restriction strength training in patients with COPD: a randomised single-blind pilot study
WHAT IS ALREADY KNOWN ON THIS TOPICLow-load blood flow restriction training (LL-BFRT) enhances strength equal to high-load...
Remote vision-based digital patient monitoring of pulse and respiratory rates in acute medical wards
Remote vision-based digital patient monitoring of pulse and respiratory rates in acute medical wards
IntroductionRegular measurement of vital signs in patients on acute wards detects or predicts clinical deterioration.1 Typ...
Airway smooth muscle and long-term clinical efficacy following bronchial thermoplasty in severe asthma
Airway smooth muscle and long-term clinical efficacy following bronchial thermoplasty in severe asthma
IntroductionBronchial thermoplasty (BT) is a bronchoscopic treatment option for patients with severe asthma, showing clini...
Correction: Night shift work is associated with an increased risk of asthma
Correction: Night shift work is associated with an increased risk of asthma
Maidstone RJ, Turner J, Vetter C, et al. Night shift work is associated with an increased risk of asthma. Thorax 2021;76:5...
Novel electromagnetic navigation bronchoscopy system for the diagnosis of peripheral pulmonary nodules: a prospective, multicentre study
Novel electromagnetic navigation bronchoscopy system for the diagnosis of peripheral pulmonary nodules: a prospective, multicentre study
WHAT IS ALREADY KNOWN ON THIS TOPICElectromagnetic navigation bronchoscopy (ENB) has been shown to improve the diagnostic ...
Readmission following hospital admission for community-acquired pneumonia in England
Readmission following hospital admission for community-acquired pneumonia in England
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Moving mountains in community-acquired pneumonia: stone by stone we progress
Moving mountains in community-acquired pneumonia: stone by stone we progress
Community-acquired pneumonia (CAP) is a leading cause of hospitalisation with high inpatient mortality. Mortality and morb...
Increasing respiratory burden of prematurity: can we turn the tide?
Increasing respiratory burden of prematurity: can we turn the tide?
Despite many improvements in neonatal care, prematurity remains a significant cause of childhood mortality and morbidity, ...
Outcomes of systemic sclerosis associated interstitial lung disease patients with a persistent inflammatory phenotype based on serial CRP measurements
Outcomes of systemic sclerosis associated interstitial lung disease patients with a persistent inflammatory phenotype based on serial CRP measurements
Interstitial lung disease (ILD) is a serious complication of systemic sclerosis (SSc) with a variable clinical trajectory....
Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study
Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSUsing routinely collected data from primary care practice in the UK...
Atopic and non-atopic effects of fish oil supplementation during pregnancy
Atopic and non-atopic effects of fish oil supplementation during pregnancy
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Phenotyping by persistent inflammation in systemic sclerosis associated interstitial lung disease: a EUSTAR database analysis
Phenotyping by persistent inflammation in systemic sclerosis associated interstitial lung disease: a EUSTAR database analysis
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Fragmentation of care between intensive and primary care settings and opportunities for improvement
Fragmentation of care between intensive and primary care settings and opportunities for improvement
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Early experience of a new national lung allocation scheme in the UK based on clinical urgency
Early experience of a new national lung allocation scheme in the UK based on clinical urgency
IntroductionIn the UK, there are five adult lung transplant centres. Until 2017, for the purpose of donor lung allocation,...
Donor lung allocation scheme: how can we measure success?
Donor lung allocation scheme: how can we measure success?
The National Health Service Blood and Transplant Cardiothoracic Advisory Group, in line with the principles of priority to...
Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm
Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm
WHAT IS ALREADY KNOWN ON THIS TOPICThe literature overwhelmingly reports (although largely by spirometry only) that those ...
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