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Gut microbiota clocks in stress
Gut microbiota clocks in stress
In this study, Tofani et al. demonstrate that the gut microbiota regulates stress responsiveness in mice via the circadian...
Predicting phage–host specificity
In a recent study, Gaborieau, Vaysset, Tesson et al. developed a method to predict phage–host specificity using geno...
Designer viral receptors
In a recent study, Liu, Huang, Guo, McCallum et al. present a method to create functional, customized coronavirus receptor...
Iron gatekeeper in malaria
Loveridge and Sigala uncover a divalent metal transporter that is required for cellular iron metabolism in Plasmodium falc...
Hepatitis B and D virus entry
Hepatitis B and D virus entry
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of covalently closed circul...
The consequences of SARS-CoV-2 within-host persistence
The consequences of SARS-CoV-2 within-host persistence
SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less than a month. Yet some people ...
Methanogens implicated by DNA evidence
Methanogens implicated by DNA evidence
This Genome Watch article highlights recent findings that expand the known diversity of methanogenic archaea and the metag...
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
Shigella sonnei is a major cause of diarrhoea globally and is increasing in prevalence relative to other Shigella because ...
Tearing CRISPR apart
Tearing CRISPR apart
This study shows that the anti-CRISPR protein AcrIF25 inhibits the type I-F CRISPR–Cas system by pulling apart the f...
Malaria vaccines: a new era of prevention and control
Malaria vaccines: a new era of prevention and control
Malaria killed over 600,000 people in 2022, a death toll that has not improved since 2015. Additionally, parasites and mos...
The indoors microbiome and human health
The indoors microbiome and human health
Indoor environments serve as habitat for humans and are replete with various reservoirs and niches for microorganisms. Mic...
The oral–gut microbiome axis in health and disease
The oral–gut microbiome axis in health and disease
The human body hosts trillions of microorganisms throughout many diverse habitats with different physico-chemical characte...
Leave no transcripts behind
Leave no transcripts behind
This Genome Watch highlights the advances made in bacterial single-cell RNA sequencing, specifically in the context of hos...
Highly pathogenic H5N1 avian influenza virus outbreak in cattle: the knowns and unknowns
Competing interests Y.K. has received grant support from Daiichi Sankyo Pharmace...
Designer antibiotics
This study used structure-based drug design and modular synthesis to identify small molecules with antimicrobial activity.
Effects of climate change and human activities on vector-borne diseases
Effects of climate change and human activities on vector-borne diseases
Vector-borne diseases are transmitted by haematophagous arthropods (for example, mosquitoes, ticks and sandflies) to human...
The microbial carbon pump and climate change
The microbial carbon pump and climate change
The ocean has been a regulator of climate change throughout the history of Earth. One key mechanism is the mediation of th...
Drosophila sperm sabotage by Wolbachia prophage
This study reports a mechanism whereby Wolbachia bacteriophage proteins modulate macromolecules of developing Drosophila m...
Antimicrobial treatment and resistance in sexually transmitted bacterial infections
Antimicrobial treatment and resistance in sexually transmitted bacterial infections
Sexually transmitted infections (STIs) have been part of human life since ancient times, and their symptoms affect quality...
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide a...
Author Correction: Conservation and similarity of bacterial and eukaryotic innate immunity
In the version of the article initially published, in the “Effector-triggered immunity” section, the sentence now reading ...
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage is a major contributor to food waste and, hence, to the negative environmental sustainability impa...
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The skin barrier protects the human body from invasion by exogenous and pathogenic microorganisms. A breach in this barrie...
A never-ending defence fight
A never-ending defence fight
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, ...
Daughters remember to swarm
The data of the study suggest that bacteria possess a physiological iron memory that persists over multiple generations.
Staphylococcus aureus gets itchy
Staphylococcus aureus gets itchy
This study reports a mechanism whereby a Staphylococcus aureus protease induces itch by activating a host receptor on sens...
The honeybee microbiota and its impact on health and disease
The honeybee microbiota and its impact on health and disease
Honeybees (Apis mellifera) are key pollinators that support global agriculture and are long-established models for develop...
Jumping between hosts
In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sar...
Machine learning sheds light on microbial dark proteins
Machine learning sheds light on microbial dark proteins
This month’s Genome Watch highlights the recent use of machine learning to uncover functional ‘dark matterR...
Antibodies versus P. aeruginosa
In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing...
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