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Tearing CRISPR apart
Tearing CRISPR apart
This study shows that the anti-CRISPR protein AcrIF25 inhibits the type I-F CRISPR–Cas system by pulling apart the f...
Malaria vaccines: a new era of prevention and control
Malaria vaccines: a new era of prevention and control
Malaria killed over 600,000 people in 2022, a death toll that has not improved since 2015. Additionally, parasites and mos...
The indoors microbiome and human health
The indoors microbiome and human health
Indoor environments serve as habitat for humans and are replete with various reservoirs and niches for microorganisms. Mic...
The oral–gut microbiome axis in health and disease
The oral–gut microbiome axis in health and disease
The human body hosts trillions of microorganisms throughout many diverse habitats with different physico-chemical characte...
Leave no transcripts behind
Leave no transcripts behind
This Genome Watch highlights the advances made in bacterial single-cell RNA sequencing, specifically in the context of hos...
Highly pathogenic H5N1 avian influenza virus outbreak in cattle: the knowns and unknowns
Competing interests Y.K. has received grant support from Daiichi Sankyo Pharmace...
Designer antibiotics
This study used structure-based drug design and modular synthesis to identify small molecules with antimicrobial activity.
Effects of climate change and human activities on vector-borne diseases
Effects of climate change and human activities on vector-borne diseases
Vector-borne diseases are transmitted by haematophagous arthropods (for example, mosquitoes, ticks and sandflies) to human...
The microbial carbon pump and climate change
The microbial carbon pump and climate change
The ocean has been a regulator of climate change throughout the history of Earth. One key mechanism is the mediation of th...
Drosophila sperm sabotage by Wolbachia prophage
This study reports a mechanism whereby Wolbachia bacteriophage proteins modulate macromolecules of developing Drosophila m...
Antimicrobial treatment and resistance in sexually transmitted bacterial infections
Antimicrobial treatment and resistance in sexually transmitted bacterial infections
Sexually transmitted infections (STIs) have been part of human life since ancient times, and their symptoms affect quality...
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-attributable deaths worldwide a...
Author Correction: Conservation and similarity of bacterial and eukaryotic innate immunity
In the version of the article initially published, in the “Effector-triggered immunity” section, the sentence now reading ...
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage: impact, causative agents and control strategies
Microbial food spoilage is a major contributor to food waste and, hence, to the negative environmental sustainability impa...
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The wound microbiota: microbial mechanisms of impaired wound healing and infection
The skin barrier protects the human body from invasion by exogenous and pathogenic microorganisms. A breach in this barrie...
A never-ending defence fight
A never-ending defence fight
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, ...
Daughters remember to swarm
The data of the study suggest that bacteria possess a physiological iron memory that persists over multiple generations.
Staphylococcus aureus gets itchy
Staphylococcus aureus gets itchy
This study reports a mechanism whereby a Staphylococcus aureus protease induces itch by activating a host receptor on sens...
The honeybee microbiota and its impact on health and disease
The honeybee microbiota and its impact on health and disease
Honeybees (Apis mellifera) are key pollinators that support global agriculture and are long-established models for develop...
Jumping between hosts
In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sar...
Machine learning sheds light on microbial dark proteins
Machine learning sheds light on microbial dark proteins
This month’s Genome Watch highlights the recent use of machine learning to uncover functional ‘dark matterR...
Antibodies versus P. aeruginosa
In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing...
Keep calm with ammonia-producing microbiota
Keep calm with ammonia-producing microbiota
In this study, Wang et al. show that bacterium-derived intestinal ammonia modulates glutamine production in the mouse brai...
Urban malaria
This study provides evidence for a role of Anopheles stephensi in driving urban malaria outbreaks.
Machine learning for microbiologists
Machine learning for microbiologists
Machine learning is increasingly important in microbiology where it is used for tasks such as predicting antibiotic resist...
Mycobacterial cords
This study reports that intracellular cord formation by Mycobacterium tuberculosis is an important feature of early pathog...
Microbial murmurs — decoding hidden conversations between bacteria
Microbial murmurs — decoding hidden conversations between bacteria
This month’s Genome Watch highlights how a tailor-made search through bacterial genomes revealed the widespread pres...
Sabotage of CRISPR–Cas
Sabotage of CRISPR–Cas
This study reports the identification of an archaeal virus Acr protein that blocks the dissociation of the target RNA from...
Beneficial applications of biofilms
Beneficial applications of biofilms
Many microorganisms live in the form of a biofilm. Although they are feared in the medical sector, biofilms that are compo...
The interplay between microbial communities and soil properties
The interplay between microbial communities and soil properties
In recent years, there has been considerable progress in determining the soil properties that influence the structure of t...
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