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The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: A systematic review
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Immunomodulator AS101 restores colistin susceptibility of clinical colistin-resistant Escherichia coli and Klebsiella pneumoniae in vitro and in vivo
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Outcome of intravenous and inhaled polymyxin B treatment in patients with multidrug-resistant gram-negative bacterial pneumonia
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Risk of Clostridioides difficile infection following different antibiotics: insights from multi-source medical data
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The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell division
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A physiologically based pharmacokinetic model of voriconazole in human CNS—Integrating time-dependent inhibition of CYP3A4, genetic polymorphisms of CYP2C19 and possible transporter mechanisms
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Reduced mortality with antimicrobial stewardship guided by BioFire FilmArray Blood Culture Identification 2 panel in critically ill patients with bloodstream infection: A retrospective propensity score-matched study
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A Phase I Clinical Study: Evaluation of Safety, Tolerability, and Population Pharmacokinetic-Pharmacodynamic Target Attainment Analysis of Etimicin Sulfate Among Healthy Chinese Participants
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Verapamil enhances the activity of Caspofungin against Cryptococcus neoformans， coinciding with inhibited Ca2+/CN pathway and damage to cell wall integrity
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Predictive performance of multi-model approaches for model-informed precision dosing of piperacillin in critically ill patients
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Dual therapy based on co-formulated darunavir/ritonavir plus lamivudine for initial therapy of HIV infection: The ANDES randomized controlled trial
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The emergence of transposon-driven multidrug resistance in invasive nontypeable Haemophilus influenzae over the last decade
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Gut Colonization With Antibiotic-Resistant Escherichia coli Pathobionts Leads to Disease Severity in Ulcerative Colitis
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Mediastinitis caused by an NDM-1 Escherichia coli in a child with Dacron Sano shunt after pulmonary atresia with ventricular septal defect surgery treated with combination of aztreonam-avibactam
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Neisseria gonorrhoeae ST-1901 in Rio de Janeiro from 2006 to 2022: Phylogeny and antimicrobial resistance evolution of a well-succeeded pathogen
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Increased risk of adverse drug reactions by higher linezolid dose per weight in multidrug-resistant tuberculosis
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Pharmacodynamics of taniborbactam in combination with cefepime studied in an in vitro model of infection
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Investigation of PhoP response regulator inhibition to overcome resistance in Gram-negative clinical bacteria
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Improvement in high-density lipoprotein cholesterol in people with HIV who switched from a tenofovir alafenamide-containing regimen to cabotegravir plus rilpivirine
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Can clinical microbiology laboratories rely on disk diffusion for accurate susceptibility assessment of cefiderocol?
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Bictegravir/emtricitabine/tenofovir alafenamide as first-line treatment in naïve HIV patients in a rapid-initiation model of care: BIC-NOW clinical trial
Bictegravir/emtricitabine/tenofovir alafenamide as first-line treatment in naïve HIV patients in a rapid-initiation model of care: BIC-NOW clinical trial
Volume 63, Issue 6, June 2024, 107164Author links open overlay panel, , , , , , , , , , , , , , , , , , , Highlights•The c...
The discovery of an anti-Candida xanthone with selective inhibition of Candida albicans GAPDH
The discovery of an anti-Candida xanthone with selective inhibition of Candida albicans GAPDH
Invasive fungal infections are a severe threat with high mortality rates, especially for patients with low immune function...
Characterization of the extended substrate spectrum of the class A β-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference
Characterization of the extended substrate spectrum of the class A β-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference
β-Lactam antibiotics are the most frequently prescribed antibiotics, including penicillins, cephalosporins, and carbapenem...
Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model evaluated by mechanism-based modelling and whole genome sequencing
Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model evaluated by mechanism-based modelling and whole genome sequencing
Volume 63, Issue 6, June 2024, 107161Author links open overlay panel, , , , , , , , , , , , , , Highlights•Hypermutable bi...
Insights into betulinic acid as a promising molecule to fight the interkingdom biofilm Staphylococcus aureus–Candida albicans
Insights into betulinic acid as a promising molecule to fight the interkingdom biofilm Staphylococcus aureus–Candida albicans
The demand for antibiofilm molecules has increased over several years due to their potential to fight biofilm-associated i...
Clinical and economic evaluation of blood culture whole process optimisation in critically ill adult patients with positive blood cultures
Clinical and economic evaluation of blood culture whole process optimisation in critically ill adult patients with positive blood cultures
Volume 63, Issue 6, June 2024, 107176Author links open overlay panel, , , , , , , , , Highlights•Optimising the blood cult...
Helicobacter pylori eradication with high-dose proton pump inhibitor-amoxicillin dual therapy: A systematic review and meta-analysis
Helicobacter pylori eradication with high-dose proton pump inhibitor-amoxicillin dual therapy: A systematic review and meta-analysis
Helicobacter pylori infection had a global prevalence of >50% and is associated with many gastrointestinal diseases, in...
Head-to-head comparison of multi-dose oritavancin and dalbavancin for complicated infections: A propensity score-matched analysis
Head-to-head comparison of multi-dose oritavancin and dalbavancin for complicated infections: A propensity score-matched analysis
Oritavancin and dalbavancin are long-acting lipoglycopeptide antibiotics approved for the treatment of acute bacterial ski...
Host single nucleotide polymorphisms and biomarkers of neuronal damage and inflammation in people living with HIV
Host single nucleotide polymorphisms and biomarkers of neuronal damage and inflammation in people living with HIV
Human immunodeficiency virus (HIV) is able to penetrate the central nervous system (CNS) through the blood-brain barrier, ...
Clinical efficacy of cefiderocol-based regimens in patients with carbapenem-resistant Acinetobacter baumannii infections: New data from CREDIBLE-CR with an updated meta-analysis
Clinical efficacy of cefiderocol-based regimens in patients with carbapenem-resistant Acinetobacter baumannii infections: New data from CREDIBLE-CR with an updated meta-analysis
Funding: This study was funded by Shionogi, B.V.Competing interests: The authors declare no conflicts of interest beyond b...
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