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Management and outcome of cutaneous diphtheria in adolescent refugees in Germany, June 2022 – October 2023
Management and outcome of cutaneous diphtheria in adolescent refugees in Germany, June 2022 – October 2023
From September 2022 an increase in Corynebacterium diphtheriae (C. diphtheriae) infections was reported in Europe...
Effect of hydrocortisone-fludrocortisone combination on mortality in septic shock: a systematic review and meta-analysis
Effect of hydrocortisone-fludrocortisone combination on mortality in septic shock: a systematic review and meta-analysis
This study assessed the effect of hydrocortisone-fludrocortisone combination therapy on the mortality of patients with sep...
Enterococci independently increase the risk for initial antibiotic treatment failure and prolonged hospitalization in adult patients with complicated urinary tract infection: a retrospective cohort study
Enterococci independently increase the risk for initial antibiotic treatment failure and prolonged hospitalization in adult patients with complicated urinary tract infection: a retrospective cohort study
We aimed to investigate the impact of enterococci on initial antibiotic treatment (IAT) failure and prolonged hospitalizat...
Trajectories and predictive significance of inflammatory parameters for clinical outcome in COVID–19 patients treated with tocilizumab
Trajectories and predictive significance of inflammatory parameters for clinical outcome in COVID–19 patients treated with tocilizumab
The IL-6 receptor inhibitor tocilizumab reduces mortality and morbidity in severe cases of COVID-19 through its effects on...
Corneal snowflake – a case of infectious crystalline keratopathy after penetrating keratoplasty
Corneal snowflake – a case of infectious crystalline keratopathy after penetrating keratoplasty
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Threat of MRSA bacteremia still matters: a propensity score matching analysis
Threat of MRSA bacteremia still matters: a propensity score matching analysis
Ethical approval Ethical approval was obtained from the Institution...
Lautropia mirabilis sepsis in immunodeficiency: first report and genomic features
Lautropia mirabilis sepsis in immunodeficiency: first report and genomic features
Lautropia mirabilis is a Gram-negative, facultative anaerobic coccus, which has been detected mainly in respiratory sites ...
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome
A considerable number of patients who contracted SARS-CoV-2 are affected by persistent multi-systemic symptoms, referred t...
Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study
Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study
Despite national guidelines and use of intrapartum antibiotic prophylaxis (IAP), Streptococcus agalactiae (group B strepto...
Efficacy and safety of colistin plus beta-lactams for bone and joint infection caused by fluoroquinolone-resistant gram-negative bacilli: a prospective multicenter study
Efficacy and safety of colistin plus beta-lactams for bone and joint infection caused by fluoroquinolone-resistant gram-negative bacilli: a prospective multicenter study
The prognosis of bone and joint infections (BJI) caused by Gram-negative bacilli (GNB) worsens significantly in the face o...
Evaluation of a host-protein signature score for differentiating between bacterial and viral infections: real-life evidence from a German tertiary hospital
Evaluation of a host-protein signature score for differentiating between bacterial and viral infections: real-life evidence from a German tertiary hospital
A host-protein signature score, consisting of serum-concentrations of C-reactive protein, tumour necrosis factor-related a...
FURIN, IFNL4, and TLR2 gene polymorphisms in relation to COVID-19 severity: a case–control study in Egyptian patients
FURIN, IFNL4, and TLR2 gene polymorphisms in relation to COVID-19 severity: a case–control study in Egyptian patients
A wide range of clinical manifestations and outcomes, including liver injury, have been reported in COVID-19 patients. We ...
Xpert MTB/XDR assay: rapid TB drug resistance detection
Xpert MTB/XDR assay: rapid TB drug resistance detection
To assess the Xpert MTB/XDR assay’s efficiency in promptly detecting resistance to isoniazid, fluoroquinolones, ethi...
Interleukin-6 as a critical inflammatory marker for early diagnosis of surgical site infection after spine surgery
Interleukin-6 as a critical inflammatory marker for early diagnosis of surgical site infection after spine surgery
Early diagnosis of surgical site infections (SSIs) could prevent surgical revision. Inflammatory markers (IMs), such as pr...
Advances in contezolid: novel oxazolidinone antibacterial in Gram-positive treatment
Advances in contezolid: novel oxazolidinone antibacterial in Gram-positive treatment
The principal objective of this project was to review and thoroughly examine the chemical characteristics, pharmacological...
The prevalence of human papillomavirus in ocular surface squamous neoplasia in HIV positive and negative patients in a South African population
The prevalence of human papillomavirus in ocular surface squamous neoplasia in HIV positive and negative patients in a South African population
To assess the prevalence and subtypes of Human Papillomavirus (HPV) in Ocular Surface Squamous Neoplasia (OSSN) in Human I...
Occult hepatitis B infection in children born to HBeAg-positive women confers a low long-term risk for HBsAg-positive infection
Occult hepatitis B infection in children born to HBeAg-positive women confers a low long-term risk for HBsAg-positive infection
Mother-to-child transmission (MTCT) has been the main cause of chronic hepatitis B virus (HBV) infection, particularly in ...
Adherence to and clinical utility of “quality indicators” for Staphylococcus aureus bacteremia: a retrospective, multicenter study
Adherence to and clinical utility of “quality indicators” for Staphylococcus aureus bacteremia: a retrospective, multicenter study
We aimed to improve the prognosis, treatment, and management of Staphylococcus aureus bacteremia (SAB) by evaluating the a...
Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI)
Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI)
To confirm the diagnosis of periprosthetic joint infection (PJI), the Infectious Diseases Society of America (IDSA) and th...
Association of common maternal infections with birth outcomes: a multinational cohort study
Association of common maternal infections with birth outcomes: a multinational cohort study
It is unclear whether common maternal infections during pregnancy are risk factors for adverse birth outcomes. We assessed...
Ceftazidime-avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infection: a systemic review and meta-analysis
Ceftazidime-avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infection: a systemic review and meta-analysis
This meta-analysis was conducted to compare the efficacy of ceftazidime-avibactam combination therapy with that of monothe...
Compassionate use of cefiderocol in a complex case of extensively drug-resistant Acinetobacter baumannii fracture-related infection: a comprehensive approach and multidisciplinary management
Compassionate use of cefiderocol in a complex case of extensively drug-resistant Acinetobacter baumannii fracture-related infection: a comprehensive approach and multidisciplinary management
Fracture-related infections (FRI) pose a difficult management problem, as they require numerous surgical interventions and...
Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study
Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study
Coronavirus disease 2019 (COVID-19) and non-COVID-19 community-acquired pneumonia (NC-CAP) often result in hospitalization...
Clinical phenotype of anaerobic bacteremia unaccompanied by detectable abscess lesion: a 10-year retrospective, multicenter, observational-cohort study
Clinical phenotype of anaerobic bacteremia unaccompanied by detectable abscess lesion: a 10-year retrospective, multicenter, observational-cohort study
Despite the importance of abscess lesions in clinical decisions regarding anaerobic bacteremia (AB), their impact on clini...
Systemic immune markers and infection risk in preterm infants fed human milk fortified with bovine colostrum or conventional fortifier, a secondary analysis of the FortiColos trial
Systemic immune markers and infection risk in preterm infants fed human milk fortified with bovine colostrum or conventional fortifier, a secondary analysis of the FortiColos trial
For very preterm infants, human milk is often fortified with formula products based on processed bovine milk. Intact bovin...
Winning entry of the creative competition
Winning entry of the creative competition
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Natural course of AIDS following HIV-2 infection
Natural course of AIDS following HIV-2 infection
In a 21-year-old female, AIDS following infection with HIV-2 was diagnosed alongside an HIV-associated high-grade B cell l...
Clinical phenotype and outcome of persistent SARS-CoV-2 replication in immunocompromised hosts: a retrospective observational study in the Omicron era
Clinical phenotype and outcome of persistent SARS-CoV-2 replication in immunocompromised hosts: a retrospective observational study in the Omicron era
This study aims to describe clinical, virological and radiological characteristics as well as treatment strategies and out...
Social and clinical predictors of perianal colonisation by multidrug-resistant bacteria for geriatric patients in the internal medicine service
Social and clinical predictors of perianal colonisation by multidrug-resistant bacteria for geriatric patients in the internal medicine service
Colonisation by multidrug-resistant (MDR) bacteria is a global health issue. The identification of patients with a higher ...
Postpartum cryptococcosis in an HIV-negative patient
Postpartum cryptococcosis in an HIV-negative patient
We present an unusual case of an HIV-negative patient with postpartum pulmonary cryptococcosis and cryptococcemia. The dia...
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