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SCI Abstract
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A Cluster Randomized Study to Explore Case Definitions, Clinical Course and Consequences of RSV in Community-Dwelling Adults Aged ≥ 50 Years
In Europe, surveillance of respiratory syncytial virus (RSV) has been recently incorporated into existing influenza monito...
Infectious Diseases And Therapy
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Long-Term Health Outcomes of People with HIV Engaged in Chemsex: A Prospective Cohort Study on Drug Use, Sexual Behaviour, Sexually-Transmitted Infections and Vulnerability
Chemsex, the intentional use of drugs to enhance sexual experiences among gay, bisexual, and other men who have sex with m...
Infectious Diseases And Therapy
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Can We Lower the Burden of Antimicrobial Resistance (AMR) in Heavily Immunocompromised Patients? A Narrative Review and Call to Action
Effective antibiotics are a cornerstone of treatment for heavily immunocompromised patients such as those undergoing cance...
Infectious Diseases And Therapy
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Comparison of Effectiveness between Ceftazidime/Avibactam and Other Active Therapies for Oxacillinase-48-Producing Carbapenem-Resistant Bacteremia in Taiwan
Oxacillinase-48 (OXA-48)-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) infections have been increasingly rep...
Infectious Diseases And Therapy
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A Cohort Study of Pediatric Severe Community-Acquired Pneumonia Involving AI-Based CT Image Parameters and Electronic Health Record Data
Community-acquired pneumonia (CAP) is a significant concern for children worldwide and is associated with a high morbidity...
Infectious Diseases And Therapy
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Safety and Efficacy of Fecal Microbiota, Live-jslm to Prevent Recurrent Infection in Participants With Irritable Bowel Syndrome
The safety and efficacy of microbiota-based products in patients with irritable bowel syndrome (IBS) and recurrent Clostri...
Infectious Diseases And Therapy
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A Cost-Effectiveness Analysis of the Switch to 20-Valent Pneumococcal Conjugate Vaccine from Lower-Valent Pneumococcal Conjugate Vaccines in the French Pediatric Population
The pneumococcal conjugate vaccine (PCV) with valency of 20 (PCV20) was approved for pediatric use by the European Commiss...
Infectious Diseases And Therapy
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Effectiveness of a Single Dose of Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in Children: A Systematic Literature Review
While pneumococcal conjugate vaccines (PCVs) are typically administered to infants using a three- or four-dose regimen, ch...
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Hepatocellular Carcinoma Recurrence in Patients with Chronic Hepatitis C Infection Treated with Direct-Acting Antivirals: A Systematic Review and Meta-Analysis
Reports of direct-acting antivirals (DAA) use for chronic hepatitis C virus (HCV) infection after successful trea...
Infectious Diseases And Therapy
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Cost-Effectiveness Analysis of Influenza Treatments in Japan Using a Transmission Model: The Impact of Baloxavir and Oseltamivir Shares
Influenza is a highly transmissible respiratory viral infection, with a risk of severe complications and excess respirator...
Infectious Diseases And Therapy
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Effective Management of Carbapenem-Resistant Enterobacterales Bloodstream Infection with Organ Dissemination in Prolonged Severe Agranulocytosis Patients with Hematological Malignancy Through Combination Therapies Including Eravacycline
This study reports three patients with hematologic malignancy patients and Carbapenem-resistant Enterobacterales ...
Infectious Diseases And Therapy
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Optimizing Clinical Indicators in Hematologic Malignancies and Sepsis Using ddPCR: A Retrospective Study
Early antibacterial treatment is critical for patients with hematologic malignancies (HMs) and sepsis. Droplet digital pol...
Infectious Diseases And Therapy
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RSV Testing Patterns and Characteristics Associated with RSV Testing Among Adults Aged 50 Years or Older in the United States
Respiratory syncytial virus (RSV) is a common respiratory virus that can cause severe disease, particularly in older adult...
Infectious Diseases And Therapy
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Epidemiology and Course of Infections in Germany: Retrospective Analysis of German Health Claims Data
Clostridioides difficile infection (CDI) is the leading cause of healthcare-associated infectious diarrhea, with recurrenc...
Infectious Diseases And Therapy
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From Colonisation to Infection: Assessing the BSI Potential in Patients with KPC, NDM, VRE and CRAB Rectal Colonisation
Multi-drug-resistant organisms (MDROs) that mostly contribute to nosocomial infections include carbapenem-resistant Entero...
Infectious Diseases And Therapy
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Programmatic Assessment of Ethambutol-Related Optic Neuropathy in Patients with Mycobacterial Infections: A Prospective Observational Cohort Study
Comprehensive data on ethambutol (EMB)-related optic neuropathy (EON) are lacking, creating a knowledge gap. Accordingly, ...
Infectious Diseases And Therapy
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Efficacy and Safety of Entecavir, Tenofovir Disoproxil Fumarate, and Tenofovir Alafenamide Fumarate in Treating Acute-on-Chronic Liver Failure with Hepatitis B Virus: A Network Meta-analysis
Oral nucleos(t)ide analogues (NAs) are widely used in managing hepatitis B virus-associated acute-on-chronic liver failure...
Infectious Diseases And Therapy
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A New Era in Tuberculosis Prevention and Treatment: Breakthroughs in Drug Development and Future Prospects
Tuberculosis (TB) remains a significant global public health challenge, despite recent advances in drug development. Howev...
Infectious Diseases And Therapy
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Evaluating the Effectiveness of mRNA-1273.815 Against COVID-19 Hospitalization Among Adults Aged ≥ 18 Years in the United States
In September 2023 the Food and Drug Administration (FDA) approved an updated mRNA COVID-19 vaccine targeting the XBB.1.5 s...
Infectious Diseases And Therapy
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Detection of Phage’s Lytic Activity Against Carbapenemase-Producing Klebsiella pneumoniae Isolates Using a High-Throughput Microbroth Growth Inhibition Assay
The host range of phages is usually assessed with the agar overlay method. However, this method is both cumbersome and sub...
Infectious Diseases And Therapy
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Antifungal Treatment for Japanese Patients with Chronic Pulmonary Aspergillosis
Despite the ongoing efforts to refine treatment durations and methods for patients with chronic pulmonary aspergillosis, t...
Infectious Diseases And Therapy
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Residual HCV-RNA and Elevated Platelet-to-Lymphocyte Ratio Predict Poor Long-Term Outcomes in Patients with Chronic Hepatitis C After Treatment
Despite achieving sustained viral response (SVR) after treatment with direct-acting antivirals (DAAs), the risk of liver d...
Infectious Diseases And Therapy
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SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study
The use of antibody titers against SARS-CoV-2, as a method of estimating subsequent infection following infection or vacci...
Infectious Diseases And Therapy
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Epidemiology and Antimicrobial Resistance of Stenotrophomonas maltophilia in China, 2014–2021
Stenotrophomonas maltophilia is an opportunistic pathogen associated with various nosocomial infections and is known for i...
Infectious Diseases And Therapy
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Burden of Acute Respiratory Infections Caused by Influenza Virus, Respiratory Syncytial Virus, and SARS-CoV-2 with Consideration of Older Adults: A Narrative Review
Influenza virus, respiratory syncytial virus (RSV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a...
Infectious Diseases And Therapy
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The Impact of Vaccination on COVID-19, Influenza, and Respiratory Syncytial Virus-Related Outcomes: A Narrative Review
Vaccination represents a core preventive strategy for public health, with interrelated and multifaceted effects across hea...
Infectious Diseases And Therapy
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A Narrative Review of Key Risk Factors for Severe Illness Following SARS-CoV-2, Influenza Virus, and Respiratory Syncytial Virus Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza, and respiratory syncytial virus (RSV) are highly ...
Infectious Diseases And Therapy
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Carbapenemase-Producing Enterobacterales from Patients Arriving from Ukraine in Poland, March 2022–February 2023
Despite a scarcity of data, before 2022 Ukraine was already considered a high-prevalence country for carbapenemas...
Infectious Diseases And Therapy
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Efficacy and Limitations of Continuous Local Antibiotic Perfusion in Treating Surgical Site Infections Following Instrumented Spinal Surgery: A Retrospective Multicenter Study
Surgical site infection (SSI) is one of the most serious postoperative complications following instrumented spinal surgery...
Infectious Diseases And Therapy
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Effectiveness of AZD7442 (Tixagevimab/Cilgavimab) for Pre-Exposure Prophylaxis Against COVID-19 Hospitalization in Israel During the Omicron Sub-Variant Time Period
The effectiveness of AZD7442 (tixagevimab/cilgavimab) against COVID-19 hospitalizations was determined at 3 and 6 ...
Infectious Diseases And Therapy
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