Fabris L, Sato K, Alpini G, Strazzabosco M. The tumor microenvironment in cholangiocarcinoma progression. Hepatology. 2021;73(1):75–85
Palmieri LJ, Lavolé J, Dermine S, et al. The choice for the optimal therapy in advanced biliary tract cancers: chemotherapy, targeted therapies or immunotherapy. Pharmacol Ther. 2020;210: 107517
Article PubMed CAS Google Scholar
O’Rourke CJ, Munoz-Garrido P, Andersen JB. Molecular targets in cholangiocarcinoma. Hepatology. 2021;73(Suppl 1):62–74
Gump JM, Thorburn A. Autophagy and apoptosis: what is the connection. Trends Cell Biol. 2011;21(7):387–392
Article PubMed PubMed Central CAS Google Scholar
Mariño G, Niso-Santano M, Baehrecke EH, Kroemer G. Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol. 2014;15(2):81–94
Article PubMed PubMed Central Google Scholar
Burke PJ. Mitochondria, bioenergetics and apoptosis in cancer. Trends Cancer. 2017;3(12):857–870
Article PubMed PubMed Central CAS Google Scholar
Wang L, Zhu Y, Zhang L, et al. Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases. Cell Death Dis. 2023;14(12):851
Article PubMed PubMed Central Google Scholar
Lu JL, Yu CX, Song LJ. Programmed cell death in hepatic fibrosis: current and perspectives. Cell Death Discov. 2023;9(1):449
Article PubMed PubMed Central Google Scholar
Zhang HR, Li YP, Shi ZJ, et al. Triptolide induces PANoptosis in macrophages and causes organ injury in mice. Apoptosis. 2023;28(11–12):1646–1665
Article PubMed CAS Google Scholar
Pandeya A, Kanneganti TD. Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes. Trends Mol Med. 2023;S1471–4914(23):00236–00238
Zhou L, Lyu J, Liu F, Su Y, Feng L, Zhang X. Immunogenic PANoptosis-initiated cancer sono-immune reediting nanotherapy by iteratively boosting cancer immunity cycle. Adv Mater. 2023;36(2):e2305361
Shi X, Gao X, Liu W, et al. Construction of the panoptosis-related gene model and characterization of tumor microenvironment infiltration in hepatocellular carcinoma. Oncol Res. 2023;31(4):569–590
Article PubMed PubMed Central Google Scholar
Wei Y, Lan C, Yang C, et al. Robust analysis of a novel PANoptosis-related prognostic gene signature model for hepatocellular carcinoma immune infiltration and therapeutic response. Sci Rep. 2023;13(1):14519
Article PubMed PubMed Central CAS Google Scholar
Song F, Wang CG, Mao JZ, et al. PANoptosis-based molecular subtyping and HPAN-index predicts therapeutic response and survival in hepatocellular carcinoma. Front Immunol. 2023;14:1197152
Article PubMed PubMed Central CAS Google Scholar
Zhang B, Huang B, Zhang X, et al. PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer. Front Oncol. 2023;13:1217654
Article PubMed PubMed Central CAS Google Scholar
Wei S, Chen Z, Ling X, Zhang W, Jiang L. Comprehensive analysis illustrating the role of PANoptosis-related genes in lung cancer based on bioinformatic algorithms and experiments. Front Pharmacol. 2023;14:1115221
Article PubMed PubMed Central CAS Google Scholar
Hu Q, Wang R, Zhang J, Xue Q, Ding B. Tumor-associated neutrophils upregulate PANoptosis to foster an immunosuppressive microenvironment of non-small cell lung cancer. Cancer Immunol Immunother. 2023;72(12):4293–4308
Article PubMed PubMed Central CAS Google Scholar
Zhang C, Xia J, Liu X, et al. Identifying prognostic genes related PANoptosis in lung adenocarcinoma and developing prediction model based on bioinformatics analysis. Sci Rep. 2023;13(1):17956
Article PubMed PubMed Central CAS Google Scholar
Wang Y, Zhou J, Zhang N, et al. A novel defined PANoptosis-related miRNA signature for predicting the prognosis and immune characteristics in clear cell renal cell carcinoma: a miRNA signature for the prognosis of ccRCC. Int J Mol Sci. 2023;24(11):9392
Article PubMed PubMed Central CAS Google Scholar
Liu W, Qu C, Wang X. Comprehensive analysis of the role of immune-related PANoptosis lncRNA model in renal clear cell carcinoma based on RNA transcriptome and single-cell sequencing. Oncol Res. 2023;31(4):543–567
Article PubMed PubMed Central Google Scholar
Malireddi R, Tweedell RE, Kanneganti TD. PANoptosis components, regulation, and implications. Aging (Albany NY). 2020;12(12):11163–11164
Malireddi R, Kesavardhana S, Kanneganti TD. ZBP1 and TAK1: Master Regulators of NLRP3 inflammasome/pyroptosis, apoptosis, and necroptosis (PAN-optosis). Front Cell Infect Microbiol. 2019;9:406
Article PubMed PubMed Central CAS Google Scholar
Karki R, Sharma BR, Lee E, et al. Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer. JCI Insight. 2020;5(12): e136720
Article PubMed PubMed Central Google Scholar
Samir P, Malireddi R, Kanneganti TD. The PANoptosome: a deadly protein complex driving pyroptosis, apoptosis, and necroptosis (PANoptosis). Front Cell Infect Microbiol. 2020;10:238
Article PubMed PubMed Central CAS Google Scholar
Briard B, Malireddi R, Kanneganti TD. Role of inflammasomes/pyroptosis and PANoptosis during fungal infection. PLoS Pathog. 2021;17(3): e1009358
Article PubMed PubMed Central CAS Google Scholar
Jiang M, Qi L, Li L, Wu Y, Song D, Li Y. Caspase-8: A key protein of cross-talk signal way in “PANoptosis” in cancer. Int J Cancer. 2021;149(7):1408–1420
Article PubMed CAS Google Scholar
Lee S, Karki R, Wang Y, Nguyen LN, Kalathur RC, Kanneganti TD. AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence. Nature. 2021;597(7876):415–419
Article PubMed PubMed Central CAS Google Scholar
Place DE, Lee S, Kanneganti TD. PANoptosis in microbial infection. Curr Opin Microbiol. 2021;59:42–49
Article PubMed CAS Google Scholar
Nguyen LN, Kanneganti TD. PANoptosis in viral infection: the missing puzzle piece in the cell death field. J Mol Biol. 2022;434(4): 167249
Article PubMed CAS Google Scholar
Kinoshita M, Kobayashi S, Gotoh K, et al. Heterogeneity of treg/Th17 according to cancer progression and modification in biliary tract cancers via self-producing cytokines. Dig Dis Sci. 2020;65(10):2937–2948
Article PubMed CAS Google Scholar
Shiode Y, Kodama T, Shigeno S, et al. TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation. Hepatology. 2023;77(2):395–410
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