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The combined analysis of metabolomics and transcriptomics revealed the metabolic changes of kidney tissue in mice with IgA nephropathy
Volume 117, Issue 5, September 2025, 111076Author links open overlay panel, , , , , , , Highlights•IgAN mice exhibit abnor...
Identification of microRNA-mRNA regulatory network associated with microplastic exposure in Mytilus galloprovincialis
The ever-growing plastics production and their natural fragmentation in micro- and nanoparticles have made plastic debris ...
Integrating multi-omics analysis to uncover the impact of PLXNA1 on the progression of esophageal cancer cells
Transcriptomics, proteomics, phosphoproteomics, and comprehensive multi-omics analysis were conducted to investigate the r...
A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through lncRNA genes
Volume 117, Issue 5, September 2025, 111085Author links open overlay panel, , , , , , , Highlights•This study first reveal...
Global transcriptome characterization of peripheral blood mononuclear cells in individuals with chronic HIV infection
BackgroundAcquired Immune Deficiency Syndrome (AIDS), resulting from Human Immunodeficiency Virus (HIV) infection, is one ...
Genotypic and phenotypic characteristics of group B streptococcal isolates from neonates in a tertiary hospital in Qingyang, Gansu Province, China
Group B Streptococcus (GBS) causes severe neonatal infections, leading to high mortality rates. This study aimed to invest...
A proposed Lawsonella species with distinct functional features from L. clevelandensis revealed by metagenomics
The skin serves as a vital barrier, largely influenced by the commensal microbiota. Lawsonella clevelandensis, the current...
Exploring the mechanism of action of trastuzumab-induced cardiomyocyte atrophy based on the FN1/PI3K/AKT-mediated mTOR-independent signaling pathway
Trastuzumab (TRZ) is a standard drug for the treatment of HER-2-positive breast cancer, but its cardiotoxicity seriously a...
Candidate effector proteins revealed by transcriptional profiling during development of Moniliophthora roreri, a fungal pathogen of Theobroma cacao
Frosty pod rot (FPR), caused by Moniliophthora roreri, is one of the most devastating diseases of cocoa plantations in the...
High-resolution genome-wide profiling reveals intricate relationship between DNA damage and sperm physiology
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Integration of transcriptome and metabolome reveals candidate metabolites responding to drought stress in sugarcane
Drought stress severely restricts sugarcane (Saccharum spp. cultivars) productivity, a globally vital sugar crop, yet the ...
Decoding oxygen preference: Machine learning discovers functional genes in Bacteria
Volume 117, Issue 5, September 2025, 111095Author links open overlay panel, , , , , , , Highlights•Random Forest model pre...
Ferulic acid mediates Mongolian horse skeletal muscle fiber remodeling through PDK1
Ferulic acid (FA), a natural antioxidant and major active component in Angelica sinensis, has beneficial effects on skelet...
The cross-talk between the metabolome and microbiome in a double-hit neonatal rat model of bronchopulmonary dysplasia
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Identification of CCR7 as a potential biomarker in polycystic ovary syndrome through transcriptome sequencing and integrated bioinformatics
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Genomic regions associated with Holstein heifer times bred to artificial insemination and embryo transfer services
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Rapid sequencing and identification for 18-STRs long amplicon panel using portable devices and nanopore sequencer
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Transcriptome and metabolome revealed the effects of hypoxic environment on ovarian development of Tibetan sheep
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Evolutionary dynamics of repetitive elements and their relationship with genome size in Acrididae
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“Genome-based in silico assessment of biosynthetic gene clusters in Planctomycetota: Evidences of its wide divergent nature”
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