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Host determinants and responses underlying SARS-CoV-2 liver tropism
Host determinants and responses underlying SARS-CoV-2 liver tropism
Hepatic sequelae are frequently reported in coronavirus disease 2019 cases and are correlated with increased disease sever...
Differences and similarities between innate immune evasion strategies of human coronaviruses
Differences and similarities between innate immune evasion strategies of human coronaviruses
So far, seven coronaviruses have emerged in humans. Four recurring endemic coronaviruses cause mild respiratory symptoms. ...
Neuroinvasion and neurotropism of severe acute respiratory syndrome coronavirus 2 infection
Neuroinvasion and neurotropism of severe acute respiratory syndrome coronavirus 2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019, contributes...
Renal implications of coronavirus disease 2019: insights into viral tropism and clinical outcomes
Renal implications of coronavirus disease 2019: insights into viral tropism and clinical outcomes
In recent years, multiple coronaviruses have emerged, with the latest one, severe acute respiratory syndrome coronavirus 2...
The expanding universe of contractile injection systems in bacteria
The expanding universe of contractile injection systems in bacteria
Contractile injection systems (CISs) are phage tail–like machineries found in a wide range of bacteria. They are often dep...
Getting to the point: unipolar growth of Hyphomicrobiales
Getting to the point: unipolar growth of Hyphomicrobiales
The governing principles and suites of genes for lateral elongation or incorporation of new cell wall material along the l...
Proteomic composition of eukaryotic and bacterial RNA decay condensates suggests convergent evolution
Proteomic composition of eukaryotic and bacterial RNA decay condensates suggests convergent evolution
Historically, membrane-less compartments have been described as granules, foci, cellular bodies, cellular aggregates, and ...
The type IVc pilus: just a Tad different
The type IVc pilus: just a Tad different
Bacteria utilize type IV pili (T4P) to interact with their environment, where they facilitate processes including motility...
The intricate organizational strategy of nucleus-forming phages
The intricate organizational strategy of nucleus-forming phages
Subcellular organization is important for all forms of life. Even viruses are known to create replication factories and ad...
Cell wall synthesizing complexes in Mycobacteriales
Cell wall synthesizing complexes in Mycobacteriales
Members of the order Mycobacteriales are distinguished by a characteristic diderm cell envelope, setting them apart from o...
Bacterial synthase-dependent exopolysaccharide secretion: a focus on cellulose
Bacterial synthase-dependent exopolysaccharide secretion: a focus on cellulose
Bacterial biofilms are a prevalent multicellular life form in which individual members can undergo significant functional ...
Function of autophagy genes in innate immune defense against mucosal pathogens
Function of autophagy genes in innate immune defense against mucosal pathogens
Mucosal surfaces are the first line of contact for most pathogens, with the respiratory, intestinal, and reproductive trac...
Virulence-associated factors as targets for phage infection
Virulence-associated factors as targets for phage infection
Bacterial pathogens can infect a wide range of hosts and pose a threat to public and animal health as well as to agricultu...
The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases
The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases
Bacteria are known to produce amyloids, proteins characterized by a conserved cross-beta sheet structure, which exhibit st...
Regulation of sexual commitment in malaria parasites — a complex affair
Regulation of sexual commitment in malaria parasites — a complex affair
Malaria blood stage parasites commit to either one of two distinct cellular fates while developing within erythrocytes of ...
Histone code: a common language and multiple dialects to meet the different developmental requirements of apicomplexan parasites
Histone code: a common language and multiple dialects to meet the different developmental requirements of apicomplexan parasites
The interaction between the nucleosome and the DNA wrapped around it has direct effects on chromatin structure at the gene...
Transcript tinkering: RNA modifications in protozoan parasites
Transcript tinkering: RNA modifications in protozoan parasites
Apicomplexan and trypanosomatid parasites have evolved a wide range of post-transcriptional processes that allow them to r...
Time to switch gears: how long noncoding RNAs function as epigenetic regulators in Apicomplexan parasites
Time to switch gears: how long noncoding RNAs function as epigenetic regulators in Apicomplexan parasites
Apicomplexan parasites are a heterogeneous group of more than 6000 intracellular protists [1], many of which have importan...
Phage transmission strategies: are phages farming their host?
Phage transmission strategies: are phages farming their host?
Bacterial viruses (also referred to as bacteriophages or phages) are ubiquitous in nature, and although they require a hos...
PII-like signaling proteins: a new paradigm in orchestrating cellular homeostasis
PII-like signaling proteins: a new paradigm in orchestrating cellular homeostasis
Members of the PII superfamily are versatile, multitasking signaling proteins ubiquitously found in all domains of life. T...
Specialized biopolymers: versatile tools for microbial resilience
Specialized biopolymers: versatile tools for microbial resilience
Biopolymers are a chemically diverse group of high-molecular-weight molecules composed of repeating building blocks, such ...
Multilayered regulation of amino acid metabolism in Escherichia coli
Multilayered regulation of amino acid metabolism in Escherichia coli
Escherichia coli primarily constitutes 0.1–5% of the mammalian gut microbiome and can also be found in the gut of birds, r...
Unlocking the potential of optogenetics in microbial applications
Unlocking the potential of optogenetics in microbial applications
Optogenetics is a powerful approach that enables researchers to use light to dynamically manipulate cellular behavior. Sin...
Nutritional control of bacterial DNA replication
Nutritional control of bacterial DNA replication
All cells must ensure precise regulation of DNA replication initiation in coordination with growth rate and in response to...
PhoU: a multifaceted regulator in microbial signaling and homeostasis
PhoU: a multifaceted regulator in microbial signaling and homeostasis
Inorganic phosphate (Pi) is one of the essential molecules required for many biological processes, including synthesis of ...
Matching the β-oxidation gene repertoire with the wide diversity of fatty acids
Matching the β-oxidation gene repertoire with the wide diversity of fatty acids
Bacteria can use fatty acids (FAs) from their environment as carbon and energy source. This catabolism is performed by the...
The multifaceted roles of Myb domain–containing proteins in apicomplexan parasites
The multifaceted roles of Myb domain–containing proteins in apicomplexan parasites
The phylum of apicomplexan parasites is a large and diverse clade of protists that is responsible for significant diseases...
Crosstalk between (p)ppGpp and other nucleotide second messengers
Crosstalk between (p)ppGpp and other nucleotide second messengers
The remarkable ability of bacteria to colonize diverse habitats relies on their efficient response to environmental change...
Environmental adaptation and diversification of bacterial two-component systems
Environmental adaptation and diversification of bacterial two-component systems
Two-component systems (TCSs) are highly conserved signaling mechanisms that allow cells to sense and respond to diverse in...
Innovative and potential treatments for fungal central nervous system infections
Innovative and potential treatments for fungal central nervous system infections
Central nervous system (CNS) infections are caused by diverse microorganisms, including viruses, bacteria, fungi, and para...
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