∗Medical Intensive Care Unit, CHU Lille, Univ. Lille, Lille, France

†CHU Lille, Department of Biostatistics, Lille, France

‡CHU Lille, INSERM CIC-IT 1403, Lille, France

§RID-AGE, INSERM UMR 1167, Lille, France

Address reprint requests to Claire Bourel, MD, MSc, Pôle de Réanimation, Hôpital Roger Salengro, Rue Emile Laine, CHU Lille, 59037 Lille Cedex, France. E-mail: [email protected]

Received 2 Mar 2023; first review completed 21 Mar 2023; accepted in final form 2 Jun 2023

The authors report no conflicts of interest.

This work analyzes respiration-related variations in central venous pressure to predict fluid responsiveness in spontaneously breathing patients. This hemodynamic parameter could identify nonfluid responsive patients, specifically when their central venous pressure does not decrease during a standardized, deep-inspiration maneuver.

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