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Comparative mathematical modeling reveals the differential effects of high-fat diet and ketogenic diet on the PI3K-Akt signaling pathway in heart
Comparative mathematical modeling reveals the differential effects of high-fat diet and ketogenic diet on the PI3K-Akt signaling pathway in heart
Obesity is a global health concern associated with increased risk of diseases like cardiovascular conditions including isc...
Type 2 diabetes: is obesity for diabetic retinopathy good or bad? A cross-sectional study
Type 2 diabetes: is obesity for diabetic retinopathy good or bad? A cross-sectional study
The relationship between obesity and diabetic retinopathy (DR) remains controversial, and the relationship between sarcope...
S-adenosyl-L-methionine supplementation alleviates aortic dissection by decreasing inflammatory infiltration
S-adenosyl-L-methionine supplementation alleviates aortic dissection by decreasing inflammatory infiltration
Methionine, an indispensable amino acid crucial for dietary balance, intricately governs metabolic pathways. Disruption in...
Association between ultra-processed food and osteoporosis: a cross-sectional study based on the NHANES database
Association between ultra-processed food and osteoporosis: a cross-sectional study based on the NHANES database
Nutritional characteristics and additives in ultra-processed foods (UPF) are directly related to bone health. Physical act...
Impact of vitamins A, D, and homocysteine on cardiometabolic multimorbidity in Northwest China
Impact of vitamins A, D, and homocysteine on cardiometabolic multimorbidity in Northwest China
To investigate the impact of vitamin A (VA), vitamin D (VD), and homocysteine (Hcy) on cardiometabolic multimorbidity (CMM...
Consumption of dietary fiber and APOA5 genetic variants in metabolic syndrome: baseline data from the Korean Medicine Daejeon Citizen Cohort Study
Consumption of dietary fiber and APOA5 genetic variants in metabolic syndrome: baseline data from the Korean Medicine Daejeon Citizen Cohort Study
Consumption of dietary fiber has been suggested as an important aspect of a healthy diet to reduce the risk of metabolic s...
Body composition and body fat distribution in tissue-specific insulin resistance and in response to a 12-week isocaloric dietary macronutrient intervention
Body composition and body fat distribution in tissue-specific insulin resistance and in response to a 12-week isocaloric dietary macronutrient intervention
Body composition and body fat distribution are important predictors of cardiometabolic diseases. The etiology of cardiomet...
Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway
Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway
Spexin, a 14 amino acid peptide, has been reported to regulate obesity and its associated complications. However, little i...
Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice
Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice
Interplay between gut microbiota and heart, termed “gut-heart” axis, has a crucial role in the pathogenesis of...
Correction: The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Correction: The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
This study investigated the effect of uteroplacental insufficiency (UPI) on renal development by detecting metabolic alter...
Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation
Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation
To characterize potential mechanisms of fisetin on hepatic insulin resistance (IR) using network pharmacology and in vitro...
A comparative study on indicators of vitamin A status and risk factors for sensitivity and specificity of the methods to detect vitamin A deficiency
A comparative study on indicators of vitamin A status and risk factors for sensitivity and specificity of the methods to detect vitamin A deficiency
Serum retinol (SR) and retinol-binding protein (RBP) are commonly used indicators, but they are affected by infections and...
The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies
The association of serum betaine concentrations with the risk of new-onset cancers: results from two independent nested case-control studies
Evidence from epidemiologic studies on the association of circulating betaine levels with the incident risk of cancer has ...
Early adulthood weight change, midlife “Life’s essential 8” health status and risk of cardiometabolic diseases: a chinese nationwide cohort study
Early adulthood weight change, midlife “Life’s essential 8” health status and risk of cardiometabolic diseases: a chinese nationwide cohort study
The association between weight change during early adulthood and cardiometabolic diseases remains uncertain in Chinese pop...
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Whether and to what extent serum uric acid (SUA) mediates the association between combined lifestyle behaviors and type 2 ...
Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research
Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research
Dementia is a highly prevalent and costly disease characterised by deterioration of cognitive and physical capacity due to...
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut mi...
The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial
The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial
The optimization of glucose control in type-1 diabetes is challenged by postprandial glycemic variability. This study aime...
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and fl...
Prospective association between an obesogenic dietary pattern in early adolescence and metabolomics derived and traditional cardiometabolic risk scores in adolescents and young adults from the ALSPAC cohort
Prospective association between an obesogenic dietary pattern in early adolescence and metabolomics derived and traditional cardiometabolic risk scores in adolescents and young adults from the ALSPAC cohort
Dietary intake during early life may be a modifying factor for cardiometabolic risk (CMR). Metabolomic profiling may enabl...
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
Insulin resistance (IR) in hepatocytes endangers human health, and frequently results in the development of non-alcoholic ...
Effect of weight change on the association between overall and source of carbohydrate intake and risk of metabolic syndrome: Tehran lipid and glucose study
Effect of weight change on the association between overall and source of carbohydrate intake and risk of metabolic syndrome: Tehran lipid and glucose study
In this prospective cohort study, we aimed to evaluate the association between dietary carbohydrates, whole grains, refine...
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study
Healthy dietary patterns are associated with lower inflammation and cardiovascular disease (CVD) risk and adherence can be...
The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study
The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study
Macrosomia (birthweight ≥ 4 kg or ≥ 4.5 kg) is strongly associated w...
The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms
The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms
Conjugated linoleic acids (CLAs) are polyunsaturated fatty acids primarily found in dairy products and ruminant animal pro...
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999–2018
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999–2018
Higher dietary quality, including increased vegetable consumption, was associated with a reduced risk of metabolic syndrom...
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X
In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well a...
Association between dietary supplement use and mortality among US adults with diabetes: a longitudinal cohort study
Association between dietary supplement use and mortality among US adults with diabetes: a longitudinal cohort study
Despite the popularity of dietary supplements, their effectiveness and safety in patients with diabetes remain controversi...
Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial
Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial
Higher circulating levels of trimethylamine N-oxide (TMAO), which is a metabolite that can be produced by the gut microbio...
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