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Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway
Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway
Spexin, a 14 amino acid peptide, has been reported to regulate obesity and its associated complications. However, little i...
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis
This study investigated the effect of uteroplacental insufficiency (UPI) on renal development by detecting metabolic alter...
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid
Whether and to what extent serum uric acid (SUA) mediates the association between combined lifestyle behaviors and type 2 ...
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats
The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut mi...
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and fl...
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6
Insulin resistance (IR) in hepatocytes endangers human health, and frequently results in the development of non-alcoholic ...
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999–2018
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999–2018
Higher dietary quality, including increased vegetable consumption, was associated with a reduced risk of metabolic syndrom...
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X
In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well a...
Association between dietary supplement use and mortality among US adults with diabetes: a longitudinal cohort study
Association between dietary supplement use and mortality among US adults with diabetes: a longitudinal cohort study
Despite the popularity of dietary supplements, their effectiveness and safety in patients with diabetes remain controversi...
Chorionicity-associated variation in metabolic phenotype of cord blood in twin
Chorionicity-associated variation in metabolic phenotype of cord blood in twin
Monochorionic (MC) twins present a higher incidence of unfavorable clinical perinatal outcomes than dichorionic (DC) twins...
Pharmacotherapies of NAFLD: updated opportunities based on metabolic intervention
Pharmacotherapies of NAFLD: updated opportunities based on metabolic intervention
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that is becoming increasingly prevalent, and it range...
Perilipin5 protects against non-alcoholic steatohepatitis by increasing 11-Dodecenoic acid and inhibiting the occurrence of ferroptosis
Perilipin5 protects against non-alcoholic steatohepatitis by increasing 11-Dodecenoic acid and inhibiting the occurrence of ferroptosis
Non-alcoholic steatohepatitis (NASH) is a major contributor to liver cirrhosis and hepatocellular carcinoma. There remains...
Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study
Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study
Serum cholinesterase (ChE) is positively associated with incident diabetes and dyslipidemia. We aimed to investigate the r...