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A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers
A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers
Genome-wide association studies (GWAS) in long-lived human populations have led to identification of variants associated w...
Molecular cross-talk between long COVID-19 and Alzheimer’s disease
Molecular cross-talk between long COVID-19 and Alzheimer’s disease
The long COVID (coronavirus disease), a multisystemic condition following severe acute respiratory syndrome coronavirus-2 ...
Neutrophil, lymphocyte count, and neutrophil to lymphocyte ratio predict multimorbidity and mortality—results from the Baltimore Longitudinal Study on Aging follow-up study
Neutrophil, lymphocyte count, and neutrophil to lymphocyte ratio predict multimorbidity and mortality—results from the Baltimore Longitudinal Study on Aging follow-up study
Immunosenescence is the age-related changes in the immune system, namely, progressively higher levels of circulating infla...
The impact of a tDCS and cognitive training intervention on task-based functional connectivity
The impact of a tDCS and cognitive training intervention on task-based functional connectivity
Declines in several cognitive domains, most notably processing speed, occur in non-pathological aging. Given the exponenti...
The role of physical activity in the association between disability and mortality among US older adults: a nationwide prospective cohort study
The role of physical activity in the association between disability and mortality among US older adults: a nationwide prospective cohort study
To examine whether physical activity can mitigate the mortality risk associated with disability in activities of daily liv...
Intermittent fasting promotes rejuvenation of immunosenescent phenotypes in aged adipose tissue
Intermittent fasting promotes rejuvenation of immunosenescent phenotypes in aged adipose tissue
The aging of white adipose tissue (WAT) involves senescence of adipose stem and progenitor cells (ASPCs) and dysregulation...
Prognostic accuracy of 70 individual frailty biomarkers in predicting mortality in the Canadian Longitudinal Study on Aging
Prognostic accuracy of 70 individual frailty biomarkers in predicting mortality in the Canadian Longitudinal Study on Aging
The frailty index (FI) uses a deficit accumulation approach to derive a single, comprehensive, and replicable indicator of...
Longitudinal changes in the functional connectivity of individuals at risk of Alzheimer’s disease
Longitudinal changes in the functional connectivity of individuals at risk of Alzheimer’s disease
First-degree relatives of Alzheimer’s disease patients constitute a key population in the search for early markers. ...
Senolytic treatment fails to improve ovarian reserve or fertility in female mice
Senolytic treatment fails to improve ovarian reserve or fertility in female mice
Senescent cell number increases with age in different tissues, leading to greater senescent cell load, proinflammatory str...
Performance of digital technologies in assessing fall risks among older adults with cognitive impairment: a systematic review
Performance of digital technologies in assessing fall risks among older adults with cognitive impairment: a systematic review
Older adults with cognitive impairment (CI) are twice as likely to fall compared to the general older adult population. Tr...
Common synaptic inputs and persistent inward currents of vastus lateralis motor units are reduced in older male adults
Common synaptic inputs and persistent inward currents of vastus lateralis motor units are reduced in older male adults
Although muscle atrophy may partially account for age-related strength decline, it is further influenced by alterations of...
Early neurological changes in aging cervical spine: insights from PROMIS mobility assessment
Early neurological changes in aging cervical spine: insights from PROMIS mobility assessment
Many studies have shown that the prevalence of degenerative spinal cord compression increases with age. However, most case...
Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS-induced murine model of colitis
Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS-induced murine model of colitis
Colitis, a subtype of inflammatory bowel disease (IBD), is a multifactorial disorder characterized by chronic inflammation...
Fear extinction is impaired in aged rats
Fear extinction is impaired in aged rats
Normal aging is accompanied by broad loss of cognitive function in humans and rodents, including declines in cognitive fle...
Cardiorespiratory fitness is associated with cognitive performance in 80 + -year-olds: Detangling processing levels
Cardiorespiratory fitness is associated with cognitive performance in 80 + -year-olds: Detangling processing levels
Cardiorespiratory fitness is known to protect against cognitive decline in older adults. Specifically, it has been shown t...
Frontal–temporal regional differences in brain energy metabolism and mitochondrial function using 31P MRS in older adults
Frontal–temporal regional differences in brain energy metabolism and mitochondrial function using 31P MRS in older adults
Aging is a major risk for cognitive decline and transition to dementia. One well-known age-related change involves decreas...
Correction to: Role of Toll-like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects
Correction to: Role of Toll-like receptor 2 and 4 signaling pathways on the inflammatory response to resistance training in elderly subjects
Correction to: GeroScience (2014) 36:9734The legend for Figure 2 has been corrected a...
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging
The Semmelweis Study is a prospective occupational cohort study that seeks to enroll all employees of Semmelweis Universit...
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2 activator as...
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax
Emerging evidence from both clinical and preclinical studies underscores the role of aging in potentiating the detrimental...
Correction to: Functional mobility and physical fitness are improved through a multicomponent training program in institutionalized older adults
Correction to: Functional mobility and physical fitness are improved through a multicomponent training program in institutionalized older adults
Cite this articleLópez‑López, S., Abuín‑Porras, V., Berlanga, L.A. et al. Correction to: Functional mobility and physical ...
The association of leukocyte telomere length with exceptional longevity among older women
The association of leukocyte telomere length with exceptional longevity among older women
The association of leukocyte telomere length (LTL) with survival to late life with intact mobility has not been adequately...
Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques
Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques
Increasing age is associated with dysregulated immune function and increased inflammation—patterns that are also obs...
The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review
The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review
Functional decline of physiological systems during ageing leads to age-related diseases. Dietary glycine increases healthy...
Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary: a study on the challenges of unhealthy aging
Comparative analysis of health status and health service utilization patterns among rural and urban elderly populations in Hungary: a study on the challenges of unhealthy aging
The demographic transition poses a significant challenge for health systems, especially in Central and Eastern European (C...
Age-specific difference in the temporal relationships between updated cardiovascular health construct and arterial stiffness in middle-aged and older adults
Age-specific difference in the temporal relationships between updated cardiovascular health construct and arterial stiffness in middle-aged and older adults
Previous studies have found that the association between modifiable risk factors and arterial stiffness varied with age. W...
Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease
Practice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease
Early screening to determine patient risk of developing Alzheimer’s will allow better interventions and planning but...
Autonomic nervous system imbalance during aging contributes to impair endogenous anti-inflammaging strategies
Autonomic nervous system imbalance during aging contributes to impair endogenous anti-inflammaging strategies
Inflammaging refers to the age-related low grade, sterile, chronic, systemic, and long-lasting subclinical, proinflammator...
OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults
OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults
While some old adults stay healthy and non-frail up to late in life, others experience multimorbidity and frailty often ac...
Systemic inflammatory and gut microbiota responses to fracture in young and middle-aged mice
Systemic inflammatory and gut microbiota responses to fracture in young and middle-aged mice
Age is a patient-specific factor that can significantly delay fracture healing and exacerbate systemic sequelae during con...
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