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Associations of IGF-1 and IGFBP-3 with Aging and the Development of Age-Associated Diseases
Associations of IGF-1 and IGFBP-3 with Aging and the Development of Age-Associated Diseases
Aging is a complex biological process that impacts various systems of the body with changes occurring at molecular, cellul...
Artificial Intelligence in Gerontology: Data-Driven Health Management and Precision Medicine
Artificial Intelligence in Gerontology: Data-Driven Health Management and Precision Medicine
As the global population ages, healthcare systems face increasing challenges in managing the complex health needs of older...
On the Role of Sleep in the Aging Processes
On the Role of Sleep in the Aging Processes
Sleep, as a fundamental requirement for the body’s well-being, plays a crucial role in various essential biological ...
Social Virtual Reality as a Solution for Aging Services and Gerontology: Understanding the Older Adults’ Acceptance of Virtual Reality Applications
Social Virtual Reality as a Solution for Aging Services and Gerontology: Understanding the Older Adults’ Acceptance of Virtual Reality Applications
A demographic shift towards an ageing population necessitates a comprehensive examination of the quality of life of the ol...
Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats
Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats
Calorie restriction (CR: ∼20–40% below AL: ad libitum intake) can increase insulin sensitivity in various spec...
Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study
Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study
There are mixed results on the correlation between body mass index and depressive symptoms among older adults. This observ...
Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults
Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults
The Will-to-Live (WTL) scale measures desire for life and life commitment across populations. However, psychometric eviden...
Role of BKCa Channels in Pial-Vessel Dilation in Rats of Different Ages
Role of BKCa Channels in Pial-Vessel Dilation in Rats of Different Ages
Studying the mechanisms of age-related changes in vascular reactions and applying the acquired knowledge in clinics can he...
Should We Consider Water and Antibiotics to Be Geroprotectors?
Should We Consider Water and Antibiotics to Be Geroprotectors?
The authors try to consider the current situation with experimental gerontological research aimed at finding means to slow...
Larval Heat Stress Affects the Lifespan and Stress Resistance of Drosophila melanogaster Adults
Larval Heat Stress Affects the Lifespan and Stress Resistance of Drosophila melanogaster Adults
In modern conditions of constant adverse effects on living organisms, such as environmental pollution or global climate ch...
On the Concentration of Vitamins A and E in the Tissues of the Bank Vole (Myodes (Clethrionomys) glareolus) and Common Shrew (Sorex araneus) Inhabiting Karelia
On the Concentration of Vitamins A and E in the Tissues of the Bank Vole (Myodes (Clethrionomys) glareolus) and Common Shrew (Sorex araneus) Inhabiting Karelia
We have studied the concentration of vitamins A (retinol) and E (α-tocopherol) in the tissues of the bank vole (Myode...
Effects of Time-of-Day on the Expression of Autophagy Genes at the Different Stages of Age-Related Macular Degeneration-Like Retinopathy in Rat’s Retina
Effects of Time-of-Day on the Expression of Autophagy Genes at the Different Stages of Age-Related Macular Degeneration-Like Retinopathy in Rat’s Retina
Age-related macular degeneration (AMD) is a complex progressive eye disease, resulting in loss of central vision in the ag...
Validation of the Portuguese Version of the Adult Carers Quality of Life Questionnaire (AC-QoL) among Informal Carers of Stroke Survivors
Validation of the Portuguese Version of the Adult Carers Quality of Life Questionnaire (AC-QoL) among Informal Carers of Stroke Survivors
Stroke is a leading cause of disability worldwide, significantly affecting not only the health and quality of life of surv...
Peculiar Relations of Life Expectancy with Economics according to the Preston Curve and with Cultural Values according to the Hofstede Dimensions in Former Soviet Union and Yugoslavia Countries
Peculiar Relations of Life Expectancy with Economics according to the Preston Curve and with Cultural Values according to the Hofstede Dimensions in Former Soviet Union and Yugoslavia Countries
We checked whether national cultural differences according to Hofstede dimensions (HD) contribute to differences in life e...
Multiple Sclerosis. Some Features of Pathology and Prospects for Therapy. Part 1
Multiple Sclerosis. Some Features of Pathology and Prospects for Therapy. Part 1
Multiple sclerosis (MS) is among the most common diseases of the central nervous system. The disease leads to pathological...
Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Genotoxic and cytotoxic drugs, widely used in anticancer therapy, target proliferating cells and induce cell death through...
Association between Telomere Length and Geriatric Status in Centenarians
Association between Telomere Length and Geriatric Status in Centenarians
Aim: To evaluate the association between telomere length and frailty and individual geriatric syndromes in older adults. M...
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Background: The field of gerontology is actively seeking senolytics and senomorphs that can influence the quantity and act...
Senolytic Drugs: Implications for Clinical Practice
Senolytic Drugs: Implications for Clinical Practice
Studying the mechanisms of aging is one of the most important goals of modern science. A significant amount of data on the...
Brain Aging
Brain Aging
Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of li...
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
In spite of numerous studies, pathogenesis of the sporadic (not inherited) form of Alzheimer’s disease (AD) still re...
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
Despite the fact that more than 90% of tryptophan is metabolized via the kynurenine pathway, the serotonin pathway is of g...
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Many organs undergo negative changes during aging that affect their functions and ability to regenerate. In particular, th...
Demographic Indicators of Probability Models
Demographic Indicators of Probability Models
Describing mortality dynamics using average indicators without considering variability can yield average results, impeding...
Mechanisms of Neurocognitive Adaptation during Aging Process
Mechanisms of Neurocognitive Adaptation during Aging Process
Human aging is associated with an increased risk of various geriatric syndromes, cognitive impairment being among the most...
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