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Human health risks of heavy metals contamination of a water-soil-vegetables farmland system in Toke Kutaye of West Shewa, Ethiopia

Contamination of foods with heavy metals poses significant threats to human health. In this study, human health risks of h...

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The rs140668532 SNP in GSK-3β gene as a potential biomarker for Alzheimer’s disease: Insights from computational modeling

Glycogen synthase kinase-3 beta (GSK-3β) is well recognized for its role in diverse physiological processes, including apo...

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Drugs or dissection? Unraveling a diagnostic puzzle in the ED: A case report on Tizanidine-Nifedipine interaction

Lower back pain is among the top ten reasons patients visit the emergency department (ED). Tizanidine, a centrally acting ...

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Assembled human microbiome and metabolome in chronic kidney disease: Dysbiosis a double-edged sword interlinking Circ-YAP1, Circ-APOE & Circ-SLC8A1

Dysbiosis is an alteration in microbiota diversity previously elucidated in patients with chronic kidney disease (CKD). Re...

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Unveiling the molecular interactions between bisphenol A and the cell surface Toll-like receptors: Implications for immune health

Microplastic pollution is an emerging threat to the human health. In nature, microplastics release several compounds of to...

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Naringin ameliorates high-fat diet-induced hepatotoxicity and dyslipidemia in experimental rat model via modulation of anti-oxidant enzymes, AMPK and SERBP-1c signaling pathways

High-fat diet causes elevation of steatosis, dyslipidemia and oxidative stress which eventually leads to hepatic injury in...

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Analysis of pesticide residues in tomatoes from the tomato field and markets of KPK, Pakistan and their potential risk to human health

The study was designed to get a real time picture of pesticide residues in tomato samples from the fields of two districts...

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Ferroptotic- and non-ferroptotic mechanisms associated with doxorubicin-induced male reproductive dysfunction

Despite the effectiveness of doxorubicin as a chemotherapeutic agent, it exerts toxicity on non-target organs, including t...

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The effects of methamphetamine intoxication on acute kidney injury in Iraqi male addicts

Methamphetamine (METH), a synthetic derivative of amphetamine, is prescribed for disorders such as narcolepsy but is somet...

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Sub-acute polyethylene microplastic inhalation exposure induced pulmonary toxicity in wistar rats through inflammation and oxidative stress

Plastic waste, particularly polyethylene (PE) plastic bags and bottles, poses a significant environmental problem and heal...

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Genotoxic activity of glyphosate and co-formulants in glyphosate-based herbicides assessed by the micronucleus test in human mononuclear white blood cells

Glyphosate-based herbicides (GBHs) are widely used and contribute to soil, water, and air contamination. Despite differing...

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Occurrence and dietary risk assessment of chloramphenicol residues in honey products in Saudi Arabia

BackgroundChloramphenicol (CAP) is a broad-spectrum antibiotic with potentially fatal side effects, including suspected ca...

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Corrigendum to “Insights into medication-induced liver injury: Understanding and management strategies” [Toxicol. Rep. 14 (2025) 101976]

Volume 14, June 2025, 102068Author links open overlay panelVatsalya Tiwari a, Shrishti Shandily a, Jessielina Albert a, Va...

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Editorial: Special issue on Current developments in immunotherapy and related toxicities

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Berberine nanoemulsion attenuates bisphenol A-induced metabolic impairment through NF-κB signaling in the liver of rat

This study was designed to investigate the potential of Berberine nanoemulsion (BNE) to mitigate Bisphenol A (BPA)-induced...

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Determination of nitrofuran metabolites in sausage casings and crawfish using LC-Q-Orbitrap HRMS: Method development and validation

This study developed and validated an analytical method for determining four nitrofuran (NF) metabolites in sausage casing...

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Per- and polyfluorinated substances (PFAS) promote osteoclastogenesis and bone loss through PPARα activation

Per- and polyfluoroalkyl substances (PFAS) are emerging as significant environmental contaminants affecting bone health, w...

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Transgenerational toxicity of Aroclor 1232 by inhalational route in mouse model

BackgroundAroclor 1232 is a commercial mixture of polychlorinated biphenyls with inhalational toxicological implications a...

Toxicology Reports

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A review of the sidelined pollutant: Reviving the fight against heavy metal contamination in an era of emerging contaminants

Groundwater contamination by heavy metals (HMs) remains a pressing global concern, presenting substantial risks to humans,...

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Pre-treatment red cell index and metastasis status as independent predictors of overall survival in Jordanian breast cancer patients receiving chemotherapy

Breast cancer (BC) poses a global health challenge, necessitating accessible prognostic biomarkers. Systemic inflammatory ...

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Synthesis of nanohybrid consisting of taurine derived carbon dots and nanoceria for anticancer applications