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Using the global randomization test as a Mendelian randomization falsification test for the exclusion restriction assumption
Using the global randomization test as a Mendelian randomization falsification test for the exclusion restriction assumption
Mendelian randomization may give biased causal estimates if the instrument affects the outcome not solely via the exposure...
A phenome-wide association and factorial Mendelian randomization study on the repurposing of uric acid-lowering drugs for cardiovascular outcomes
A phenome-wide association and factorial Mendelian randomization study on the repurposing of uric acid-lowering drugs for cardiovascular outcomes
Uric acid has been linked to various disease outcomes. However, it remains unclear whether uric acid-lowering therapy coul...
Source-specific nitrate intake and all-cause mortality in the Danish Diet, Cancer, and Health Study
Source-specific nitrate intake and all-cause mortality in the Danish Diet, Cancer, and Health Study
Nitrate and nitrite are naturally occurring in both plant- and animal-sourced foods, are used as additives in the processi...
Cognitive ability, education, height and body mass index in relation to risk of schizophrenia and mortality following its diagnosis
Cognitive ability, education, height and body mass index in relation to risk of schizophrenia and mortality following its diagnosis
This study examines the hypotheses that the traits of higher IQ, longer education and taller height are associated with lo...
Short inter-pregnancy interval and birthweight: a reappraisal based on a follow-up study of all women in Norway with two singleton deliveries during 1970–2019
Short inter-pregnancy interval and birthweight: a reappraisal based on a follow-up study of all women in Norway with two singleton deliveries during 1970–2019
We studied mean changes in birthweight from the first to the second delivery according to length of the inter-pregnancy in...
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study
Research has indicated that sex hormone-binding globulin (SHBG) is associated with glucose homeostasis and may play a role...
Survival outcomes and healthcare utilization between immigrant patients and Danish-born patients with hematological cancers: a Danish population-based study
Survival outcomes and healthcare utilization between immigrant patients and Danish-born patients with hematological cancers: a Danish population-based study
Overall survival (OS) for patients with a hematological cancer may differ between immigrant and Danish-born patients due t...
The HOPE cohort: cohort profile and evaluation of selection bias
The HOPE cohort: cohort profile and evaluation of selection bias
The HOPE cohort is a Danish nationwide cohort with ongoing follow-up, holding information on postpartum depression (PPD) s...
Use of systemic hormonal contraception and risk of attempted suicide: a nested case–control study
Use of systemic hormonal contraception and risk of attempted suicide: a nested case–control study
Evidence regarding the role of hormonal contraception (HC) as a risk factor for attempted suicide is inconclusive. Thus, t...
Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022: a study using nationwide population data
Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022: a study using nationwide population data
While there is substantial evidence on excess mortality in the first two years of the COVID-19 pandemic, no study has cond...
Consumption of milk and other dairy products and incidence of Parkinson’s disease: a prospective cohort study in French women
Consumption of milk and other dairy products and incidence of Parkinson’s disease: a prospective cohort study in French women
Previous studies showed positive associations between milk intake and Parkinson’s disease (PD) in men but not in wom...
Reevaluating the fraction of cancer attributable to excess weight: overcoming the hidden impact of prediagnostic weight loss
Reevaluating the fraction of cancer attributable to excess weight: overcoming the hidden impact of prediagnostic weight loss
To evaluate the magnitude of the potential underestimation of the proportion of cancer cases attributable to excess weight...
Self-medication among general population in the European Union: prevalence and associated factors
Self-medication among general population in the European Union: prevalence and associated factors
Self-medication (SM) forms an important part of public health strategy. Nonetheless, little research has been performed to...
IDcare – a longitudinal register study of pre-pandemic and pandemic health care utilization and diagnostic profiles among people with intellectual disabilities in southern Sweden
IDcare – a longitudinal register study of pre-pandemic and pandemic health care utilization and diagnostic profiles among people with intellectual disabilities in southern Sweden
The aim of the creation of this cohort was to investigate patterns of health and health care utilisation before and during...
Neonatal outcomes after in utero exposure to antipsychotics: a systematic review and meta-analysis
Neonatal outcomes after in utero exposure to antipsychotics: a systematic review and meta-analysis
Adverse neonatal outcomes following in utero antipsychotic exposure remain unclear. This systematic review and meta-analys...
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
Third, we think, non-health related factors (attitudes, culture, values) that constitute a population should receive more ...
Cohort profile: the China surgery and anesthesia cohort (CSAC)
Cohort profile: the China surgery and anesthesia cohort (CSAC)
The China Surgery and Anaesthesia Cohort (CSAC) study was launched in July 2020 and is an ongoing prospective cohort study...
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
Dietary factors have been extensively investigated as possible risk factors for liver cancer, but the evidence is inconclu...
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Data regarding Alzheimer’s disease (AD) occurrence in farming populations is lacking. This study aimed to investigat...
Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older German adults
Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older German adults
Selenium is an essential trace mineral. The main function of selenoprotein P (SELENOP) is to transport selenium but it has...
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Sarcoidosis incidence peaks in women between 50 and 60 years old, which coincides with menopause, suggesting that certain ...
Vitamin D and human health: evidence from Mendelian randomization studies
Vitamin D and human health: evidence from Mendelian randomization studies
We summarized the current evidence on vitamin D and major health outcomes from Mendelian randomization (MR) studies. PubMe...
Population-based analysis of the number of thrombectomies performed after cerebral ischemic stroke and prognostic factors of mortality in France
Population-based analysis of the number of thrombectomies performed after cerebral ischemic stroke and prognostic factors of mortality in France
Study designThis retrospective study analyzed data extracted from the standard French national hospital discharge database...
Assessing the importance of primary care diagnoses in the UK Biobank
Assessing the importance of primary care diagnoses in the UK Biobank
The UK Biobank has made general practitioner (GP) data (censoring date 2016–2017) available for approximately 45% of...
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Diesel exhaust (DE) is human carcinogen with sufficient evidence only for lung cancer. Systematic evidence on other cancer...
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
The association between having older siblings and decreased risk for atopic symptoms is well-established. This has been in...
The Rotterdam Study. Design update and major findings between 2020 and 2024
The Rotterdam Study. Design update and major findings between 2020 and 2024
The Rotterdam Study is a population-based cohort study, started in 1990 in the district of Ommoord in the city of Rotterda...
Dimensions of health data Integrity
Dimensions of health data Integrity
Health data integrity, as an emergent concept, stands to reshape the lifecycle of data-driven healthcare and research, ens...
Losing the Public, for Better or for Worse: A Lesson from John Everett Gordon (1890–1983) and John Rodman Paul (1893–1971)
Losing the Public, for Better or for Worse: A Lesson from John Everett Gordon (1890–1983) and John Rodman Paul (1893–1971)
The Covid-19 pandemic has laid bare a tension around scientific expertise that has major implications for the effectivenes...
State-level economic uncertainty and cardiovascular disease deaths: evidence from the United States
State-level economic uncertainty and cardiovascular disease deaths: evidence from the United States
The relationship between economic recessions and cardiovascular mortality has been widely explored. However, there is limi...
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