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EWSR1: the promiscuous king of mesenchymal neoplasia
EWSR1: the promiscuous king of mesenchymal neoplasia
Ewing Sarcoma breakpoint region 1 (EWSR1) encodes EWSR1, a multifunctional RNA-binding protein that regulates the express...
Should a borderline negative HER2 result in a core biopsy of invasive carcinoma of the breast have HER2 assessment repeated in the excision specimen?
Should a borderline negative HER2 result in a core biopsy of invasive carcinoma of the breast have HER2 assessment repeated in the excision specimen?
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PD-L1 protein expression in breast cancer
PD-L1 protein expression in breast cancer
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Cross-sectional study to evaluate the utility of elastic tissue staining in primary cicatricial alopecia
Cross-sectional study to evaluate the utility of elastic tissue staining in primary cicatricial alopecia
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Correlation of low numbers of intratumoral FOXP3+ cells with worse progression-free survival in angioimmunoblastic T cell lymphoma
Correlation of low numbers of intratumoral FOXP3+ cells with worse progression-free survival in angioimmunoblastic T cell lymphoma
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Molecular diagnosis of tuberous sclerosis complex in fetuses and infants: an institutional case series
Molecular diagnosis of tuberous sclerosis complex in fetuses and infants: an institutional case series
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Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma
Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma
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Application of algorithmic cytomorphological assessment and immunocytochemistry with the international system for reporting serous fluid cytopathology on pericardial fluid cytology
Application of algorithmic cytomorphological assessment and immunocytochemistry with the international system for reporting serous fluid cytopathology on pericardial fluid cytology
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PAX5 and CD70 are expressed in thymic carcinoma but not in atypical thymoma (WHO type B3 thymoma): an immunohistochemical analysis of 60 cases
PAX5 and CD70 are expressed in thymic carcinoma but not in atypical thymoma (WHO type B3 thymoma): an immunohistochemical analysis of 60 cases
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Medium-term storage of frozen residual antenatal sera in gel separator tube is suitable for subsequent serological investigation of intrauterine infection
Medium-term storage of frozen residual antenatal sera in gel separator tube is suitable for subsequent serological investigation of intrauterine infection
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Pitfalls in the diagnosis and management of acid-base disorders in humans: a laboratory medicine perspective
Pitfalls in the diagnosis and management of acid-base disorders in humans: a laboratory medicine perspective
Diagnostic errors affect patient management, and as blood gas analysis is mainly performed without the laboratory, users m...
How--and why--to fill up a surgical pathology requisition form
How--and why--to fill up a surgical pathology requisition form
In his excellent review on macroscopic pathology, Shepherd refers to the lack of adequate clinical information on patholog...
Molecular and haematological characterisation of haemolytic anaemia associated with biallelic KLF1 mutations: a case series
Molecular and haematological characterisation of haemolytic anaemia associated with biallelic KLF1 mutations: a case series
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Streamlining pathology orders in a time-crunched medical world: much ado about requisitions
Streamlining pathology orders in a time-crunched medical world: much ado about requisitions
I read with fascination the paper by Neil Shepherd and the letter to the editor by Pai.1–3 Both pieces address critical is...
Phaeochromocytoma and paraganglioma
Phaeochromocytoma and paraganglioma
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Comparing the diagnostic efficacy of optical coherence tomography and frozen section for margin assessment in breast-conserving surgery: a meta-analysis
Comparing the diagnostic efficacy of optical coherence tomography and frozen section for margin assessment in breast-conserving surgery: a meta-analysis
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Does an electronic pathology ordering system change the volume and pattern of routine testing in hospital? An interrupted time series analysis
Does an electronic pathology ordering system change the volume and pattern of routine testing in hospital? An interrupted time series analysis
IntroductionWith increasing healthcare costs and an ageing population, identifying and resolving causes of low-value care ...
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
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Intraoperative evaluation of sentinel lymph nodes in patients with breast cancer treated with systemic neoadjuvant therapy
Intraoperative evaluation of sentinel lymph nodes in patients with breast cancer treated with systemic neoadjuvant therapy
WHAT IS ALREADY KNOWN ON THIS TOPICTouch preparation (TP) is an easy and rapid method to detect metastasis during intraope...
The Impact of potential 'confounders on the diagnostic sensitivity of circulating free DNA in management of FIT+ patients: a pilot study
The Impact of potential 'confounders on the diagnostic sensitivity of circulating free DNA in management of FIT+ patients: a pilot study
IntroductionMetastatic colorectal cancer (mCRC) is still one of the leading causes of death worldwide.1 Despite improvemen...
Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a clinicopathological study of three cases
Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a clinicopathological study of three cases
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Sample suitability and stability in different blood collection tubes for methanol, ethanol, isopropanol, acetone and glycols analysis
Sample suitability and stability in different blood collection tubes for methanol, ethanol, isopropanol, acetone and glycols analysis
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Performances of the Idylla GeneFusion Assay: contribution to a rapid diagnosis of targetable gene fusions in tumour samples
Performances of the Idylla GeneFusion Assay: contribution to a rapid diagnosis of targetable gene fusions in tumour samples
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Stability of porphyrins and porphyrin precursors in urine and plasma samples: implications for sample handling and storage
Stability of porphyrins and porphyrin precursors in urine and plasma samples: implications for sample handling and storage
The porphyrias are rare disorders of haem biosynthesis. Diagnosis requires demonstrating increased porphyrins or porphyrin...
Gene of the month: GATA3
Gene of the month: GATA3
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FOXL2: a gene central to ovarian function
FOXL2: a gene central to ovarian function
The FOXL2 (forkhead box L2) gene is located on chromosome 3 and encodes for forkhead box (FOX) family of transcription fac...
Emerging mesenchymal tumour types and biases in the era of ubiquitous sequencing
Emerging mesenchymal tumour types and biases in the era of ubiquitous sequencing
IntroductionSince the late 1990s, molecular genetic techniques have accelerated developments in the field of soft tissue p...
Her2 low (but not negative): the newest biomarker on the block for gastro-oesophageal adenocarcinoma
Her2 low (but not negative): the newest biomarker on the block for gastro-oesophageal adenocarcinoma
In this issue of Journal of Clinical Pathology, Angerilli et al provide a detailed survey of the prevalence and characteri...
HER2-low in gastro-oesophageal adenocarcinoma: a real-world pathological perspective
HER2-low in gastro-oesophageal adenocarcinoma: a real-world pathological perspective
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Molecular characterisation of Hb Akron [{beta}52 (D3) Asp->Val] combined with thalassaemia in a Chinese family
Molecular characterisation of Hb Akron [{beta}52 (D3) Asp->Val] combined with thalassaemia in a Chinese family
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