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Comparative analysis of ARID1A mutations with mRNA levels and protein expression in gastric carcinoma
Comparative analysis of ARID1A mutations with mRNA levels and protein expression in gastric carcinoma
The ARID1A gene is pivotal in chromatin remodeling and genomic integrity and is frequently mutated in various cancer types...
Immunohistochemical double nuclear staining for cell-specific automated quantification of the proliferation index – A promising diagnostic aid for melanocytic lesions
Immunohistochemical double nuclear staining for cell-specific automated quantification of the proliferation index – A promising diagnostic aid for melanocytic lesions
AimsPathologists often use immunohistochemical staining of the proliferation marker Ki67 in their diagnostic assessment of...
NAA10 gene expression is associated with mesenchymal transition, dedifferentiation, and progression of clear cell renal cell carcinoma
NAA10 gene expression is associated with mesenchymal transition, dedifferentiation, and progression of clear cell renal cell carcinoma
Renal cell carcinoma (RCC) represents 3–5% of adult cancers and accounts for approximately 70% of all primary renal malign...
Integrated bioinformatics approaches and expression assays identified new markers in pituitary adenomas
Integrated bioinformatics approaches and expression assays identified new markers in pituitary adenomas
Based on the latest reports of the Central Brain Tumor Registry of the USA, pituitary adenomas (PA) include 36.0 % of prim...
Immunohistochemical and molecular pattern of p53 in epithelial ovarian cancers negative for germline BRCA1/2 variants
Immunohistochemical and molecular pattern of p53 in epithelial ovarian cancers negative for germline BRCA1/2 variants
Epithelial ovarian cancers (EOC) associated with germline or somatic BRCA pathogenetic variants have a significantly highe...
Roles of lysophosphatidic acid (LPA) receptor-mediated signaling in cellular functions modulated by endothelial cells in pancreatic cancer cells under hypoxic conditions
Roles of lysophosphatidic acid (LPA) receptor-mediated signaling in cellular functions modulated by endothelial cells in pancreatic cancer cells under hypoxic conditions
The insufficient oxygen supply from arterial blood leads to tissue hypoxia. Hypoxia is a common feature of solid tumors an...
Hepatic granulomas following liver transplantation: A retrospective survey, and analysis of possible microbiological etiology
Hepatic granulomas following liver transplantation: A retrospective survey, and analysis of possible microbiological etiology
Volume 255, March 2024, 155201Author links open overlay panel, , , , , AbstractBackgroundLiver granulomas have always been...
Transcription factor RELA promotes hepatocellular carcinoma progression by promoting the transcription of m6A modulator METTL3
Transcription factor RELA promotes hepatocellular carcinoma progression by promoting the transcription of m6A modulator METTL3
Liver cancer is the sixth commonest human malignancy in the world and the second major cause of cancer-related deaths [1]....
Tumor-stroma ratio in preoperative biopsies and matched surgical specimens in oral squamous cell carcinoma: Concordance and impact on recurrence-free and overall survival
Tumor-stroma ratio in preoperative biopsies and matched surgical specimens in oral squamous cell carcinoma: Concordance and impact on recurrence-free and overall survival
Despite improvements in diagnostics and clinical as well as surgical management, oral squamous cell carcinomas (OSCC) stil...
Circulating miRNAs and lncRNAs serve as biomarkers for early colorectal cancer diagnosis
Circulating miRNAs and lncRNAs serve as biomarkers for early colorectal cancer diagnosis
According to data [1], colorectal cancer is the second most significant cause of cancer-related mortality and the third mo...
Solitary fibrous tumor occurring at unusual sites: A clinico-pathological series of 31 cases with emphasis on its wide morphological spectrum
Solitary fibrous tumor occurring at unusual sites: A clinico-pathological series of 31 cases with emphasis on its wide morphological spectrum
Solitary fibrous tumor (SFT) is a relatively rare mesenchymal fibroblastic tumor occurring most commonly in adults with no...
The immutable relevance of myeloid sarcomas: Clinicopathological study of fourteen cases
The immutable relevance of myeloid sarcomas: Clinicopathological study of fourteen cases
Myeloid neoplasms (MN) are not considered solid tumors in their entirety. Depending on their stage of differentiation and ...
Detection of EGFR T790M mutation using liquid biopsy for non-small cell lung cancer: Utility of droplet digital polymerase chain reaction vs. cobas real-time polymerase chain reaction
Detection of EGFR T790M mutation using liquid biopsy for non-small cell lung cancer: Utility of droplet digital polymerase chain reaction vs. cobas real-time polymerase chain reaction
Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) accounts for 10% - 64% of NSCLC patients...
Histopathologic and immunophenotypic characterization of patient-derived pediatric malignant hepatocellular tumor xenografts (PDXs)
Histopathologic and immunophenotypic characterization of patient-derived pediatric malignant hepatocellular tumor xenografts (PDXs)
Hepatoblastoma (HB) is the most common primary liver malignancy in children, with an estimated incidence of 1.7 cases per ...
Studying the correlation of inflammatory cytokines to COVID-19 disease
Studying the correlation of inflammatory cytokines to COVID-19 disease
Volume 255, March 2024, 155215Author links open overlay panel, , , , , , , AbstractExtreme response of the immune system d...
The priority of mesenchymal stem cells treated with melatonin in ameliorating thyroid impairment induced by amiodarone. Thorough look on the apoptotic pathway
The priority of mesenchymal stem cells treated with melatonin in ameliorating thyroid impairment induced by amiodarone. Thorough look on the apoptotic pathway
Amiodarone is a persuasive drug uses in arrhythmic therapy which is utilized by the medical practitioners for the manageme...
IL-33 immunohistochemical pattern of expression in neoplastic and nonneoplastic peripheral lung tissues of stage 1 o 2 lung adenocarcinoma
IL-33 immunohistochemical pattern of expression in neoplastic and nonneoplastic peripheral lung tissues of stage 1 o 2 lung adenocarcinoma
Interleukin 33 (IL-33), is a member of the IL-1β superfamily and of the so-called “alarmin” family. Its receptor is repres...
Conjunctival leiomyosarcoma: A clinico-pathological study with in deep molecular characterization
Conjunctival leiomyosarcoma: A clinico-pathological study with in deep molecular characterization
Leiomyosarcoma (LMS) is a malignant mesenchymal neoplasm with frequent local recurrences and distant metastases composed o...
Primary vulvar adenocarcinoma of intestinal type: Report of two cases showing molecular similarity with colorectal adenocarcinoma
Primary vulvar adenocarcinoma of intestinal type: Report of two cases showing molecular similarity with colorectal adenocarcinoma
Vulvar cancer is an uncommon condition in the female genital tract that typically affects elderly women (median age, 72–75...
Kaposi sarcoma herpesvirus/human herpesvirus 8-positive diffuse large B-cell lymphoma characterized by malignant ascites: A case report
Kaposi sarcoma herpesvirus/human herpesvirus 8-positive diffuse large B-cell lymphoma characterized by malignant ascites: A case report
Kaposi sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8)-associated multicentric Castleman disease (MCD) encompasses a g...
Compartmental Syndecan-1 (CD138) expression as a novel prognostic marker in triple-negative metaplastic breast cancer
Compartmental Syndecan-1 (CD138) expression as a novel prognostic marker in triple-negative metaplastic breast cancer
Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype, representing about 10–15% of all malignant ...
Unraveling dedifferentiation and metastasis traces in pancreatic ductal adenocarcinoma ductal cells: Insights from single-cell RNA sequencing analysis of ITGB4 and C19orf33
Unraveling dedifferentiation and metastasis traces in pancreatic ductal adenocarcinoma ductal cells: Insights from single-cell RNA sequencing analysis of ITGB4 and C19orf33
Volume 253, January 2024, 155012Author links open overlay panel, , , , , , AbstractPancreatic Ductal Adenocarcinoma (PDAC)...
Long non-coding RNA HIF1A-AS2 promotes carcinogenesis by enhancing Gli1-mediated HIF1α expression in clear cell renal cell carcinoma
Long non-coding RNA HIF1A-AS2 promotes carcinogenesis by enhancing Gli1-mediated HIF1α expression in clear cell renal cell carcinoma
Renal cell carcinoma (RCC) is considered one of the most widespread cancers affecting humans [1]. It is estimated that nea...
Emerging role and clinical implication of mRNA scavenger decapping enzyme in colorectal cancer
Emerging role and clinical implication of mRNA scavenger decapping enzyme in colorectal cancer
BackgroundTurnover of RNA is a regulated process that in part controls gene expression. This process is partly controlled ...
Dynamic analysis of predictive biomarkers for radiation therapy efficacy in non-small cell lung cancer patients by next-generation sequencing based on blood specimens
Dynamic analysis of predictive biomarkers for radiation therapy efficacy in non-small cell lung cancer patients by next-generation sequencing based on blood specimens
Lung cancer, as the malignant tumor with the highest mortality rate worldwide, causes more than 1 million deaths per year ...
Dysregulation of DNA epigenetic modulators during prostate carcinogenesis in an eastern Indian patient population: Prognostic implications
Dysregulation of DNA epigenetic modulators during prostate carcinogenesis in an eastern Indian patient population: Prognostic implications
The incidence of prostate cancer (PCa) is increasing in developing countries including India, and in some Indian metropoli...
Benign Mesothelial Cells in transbronchial biopsy specimens: A potential diagnostic pitfall for lung cancer
Benign Mesothelial Cells in transbronchial biopsy specimens: A potential diagnostic pitfall for lung cancer
Recent advances in the diagnosis and treatment of lung cancer have dramatically improved the therapeutic landscape [1]. A ...
A bioinformatics-based approach and expression assay for identification of dysregulated genes in pituitary adenoma
A bioinformatics-based approach and expression assay for identification of dysregulated genes in pituitary adenoma
Pituitary neuroendocrine tumors (PitNETs) are classified as a type of intracranial tumors [2]. Patients affected by these ...
Role of O-GlcNAcylation in cancer biology
Role of O-GlcNAcylation in cancer biology
It is well known that post-translational modification of proteins is essential to control and regulate cell processes, the...
Hsa-miR-21–5p reflects synovitis and tenosynovitis components of musculoskeletal ultrasonography Seven-joint scores in rheumatoid arthritis disease and predicts the disease flare
Hsa-miR-21–5p reflects synovitis and tenosynovitis components of musculoskeletal ultrasonography Seven-joint scores in rheumatoid arthritis disease and predicts the disease flare
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that primarily affects the joints and causes excess...
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