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Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains
Evidence showing the functional significance of the choroid plexus is accumulating. Although it is clinically well-known t...
An autopsy case of adult‐onset neuronal intranuclear inclusion disease with perivascular preservation in cerebral white matter
An autopsy case of adult‐onset neuronal intranuclear inclusion disease with perivascular preservation in cerebral white matter
Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disease characterized by appearance of eosinophilic ...
Cotton rats (Sigmodon hispidus) with a high prevalence of hydrocephalus without clinical symptoms
Cotton rats (Sigmodon hispidus) with a high prevalence of hydrocephalus without clinical symptoms
Normal-pressure hydrocephalus (NPH) is a condition in which the ventricle is enlarged without elevated cerebrospinal fluid...
Effectiveness of radiation therapy on brain invasion by human papillomavirus‐related multiphenotypic sinonasal carcinoma: A case report
Effectiveness of radiation therapy on brain invasion by human papillomavirus‐related multiphenotypic sinonasal carcinoma: A case report
Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC) is newly suggested and characterized by HPV-...
Tufted astrocyte‐like glia in two autopsy cases of multiple system atrophy: Is it a concomitant neurodegenerative disorder with multiple system atrophy and progressive supranuclear palsy?
Tufted astrocyte‐like glia in two autopsy cases of multiple system atrophy: Is it a concomitant neurodegenerative disorder with multiple system atrophy and progressive supranuclear palsy?
Tufted astrocytes are one of the core histopathological features of progressive supranuclear palsy (PSP). To our knowledge...
Glioblastoma and malignant melanoma: Serendipitous or anticipated association?
Glioblastoma and malignant melanoma: Serendipitous or anticipated association?
Volume 41, Issue 6 p. 489-491 Letter to the Editor Luigi Fiondella, Luigi Fiondella ...
Japanese Society of Neuropathology Award 2021
Japanese Society of Neuropathology Award 2021
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Clinicopathological heterogeneity of Alzheimer's disease with pure Alzheimer's disease pathology: Cases associated with dementia with Lewy bodies, very early‐onset dementia, and primary progressive aphasia
Clinicopathological heterogeneity of Alzheimer's disease with pure Alzheimer's disease pathology: Cases associated with dementia with Lewy bodies, very early‐onset dementia, and primary progressive aphasia
We report four cases depicting the heterogeneity of Alzheimer's disease (AD) associated with pure AD pathology. Case 1 was...
Let's cluster cases in Neuropathology Case Cluster series!: Unveil clinical masqueraders (Neuropathology Cluster Case 1–13)
Let's cluster cases in Neuropathology Case Cluster series!: Unveil clinical masqueraders (Neuropathology Cluster Case 1–13)
Early View Editorial Takahiro Takeda, Department of Neurology, National Hospital Orga...
Radiologic–pathologic association of tumor‐like lesions with inflammation in cerebral white matter: Comparison of two cases with distinct clinical outcomes
Radiologic–pathologic association of tumor‐like lesions with inflammation in cerebral white matter: Comparison of two cases with distinct clinical outcomes
Here, we report two cases showing tumor-like white matter lesions; one case was diagnosed as having inflammatory disease, ...
Unexpected postmortem diagnoses in cases of clinically diagnosed amyotrophic lateral sclerosis
Unexpected postmortem diagnoses in cases of clinically diagnosed amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease that is clinically and pathologically characterized by impai...
Parkinson's disease and parkinsonism: Clinicopathological discrepancies on diagnosis in three patients
Parkinson's disease and parkinsonism: Clinicopathological discrepancies on diagnosis in three patients
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The cardinal neuropathological features of...
Spinal cord‐predominant neuropathology in an adult‐onset case of POLR3A‐related spastic ataxia
Spinal cord‐predominant neuropathology in an adult‐onset case of POLR3A‐related spastic ataxia
Biallelic mutations in POLR3A have been associated with childhood-onset hypomyelinating leukodystrophies and adolescent-to...
Lewy pathology of the submandibular gland in Lewy body disease: A report of autopsy cases
Lewy pathology of the submandibular gland in Lewy body disease: A report of autopsy cases
Accumulation of phosphorylated α-synuclein in the central and peripheral nervous systems is a histological hallmark ...
“Burnt‐out” progressive multifocal leukoencephalopathy in idiopathic CD4+ lymphocytopenia
“Burnt‐out” progressive multifocal leukoencephalopathy in idiopathic CD4+ lymphocytopenia
Progressive multifocal leukoencephalopathy (PML) is a fatal disease caused by John Cunningham virus (JCV) infection; howev...
Clinicopathological features of titinopathy from a Chinese neuromuscular center
Clinicopathological features of titinopathy from a Chinese neuromuscular center
Titin, one of the largest proteins in humans, is a major component of muscle sarcomeres. Pathogenic variants in the titin ...
Ependymosarcoma harboring C11orf95:RELA fusion transcript: Report of two cases and review of the literature
Ependymosarcoma harboring C11orf95:RELA fusion transcript: Report of two cases and review of the literature
Ependymoma is a relatively rare glial tumor of the central nervous system that arise from the cells lining the ventricles ...
Spread of vimentin‐immunoreactive cells within the plaque‐like lesion in the spinal anterior horn of a patient with post‐poliomyelitis syndrome
Spread of vimentin‐immunoreactive cells within the plaque‐like lesion in the spinal anterior horn of a patient with post‐poliomyelitis syndrome
A Japanese man in the present study experienced acute weakness in his right leg as a two year old. The strength in his leg...
Intravascular large B‐cell lymphoma affecting multiple cranial nerves: A histopathological study
Intravascular large B‐cell lymphoma affecting multiple cranial nerves: A histopathological study
Intravascular large B-cell lymphoma (IVLBCL) is a rare form of lymphomas with poor prognosis, characterized by atypical ly...
LINC01123 potentially correlates with radioresistance in glioma through the miR‐151a/CENPB axis
LINC01123 potentially correlates with radioresistance in glioma through the miR‐151a/CENPB axis
Radiotherapy represents the most effective nonsurgical therapy, whereas acquired radioresistance remains a major challenge...
Selective extension of cerebral vascular calcification in an autopsy case of Fahr's syndrome associated with asymptomatic hypoparathyroidism
Selective extension of cerebral vascular calcification in an autopsy case of Fahr's syndrome associated with asymptomatic hypoparathyroidism
We report an autopsy case of Fahr's syndrome in an 85-year-old woman associated with asymptomatic hypoparathyroidism. The ...
Senile plaque calcification of the lamina circumvoluta medullaris in Alzheimer's disease
Senile plaque calcification of the lamina circumvoluta medullaris in Alzheimer's disease
Vascular calcification is a common phenomenon in the elderly, predominantly appearing in the basal ganglia and in the lami...
Intraventricular mucin‐producing glioblastoma arising in the septum pellucidum at the frontal horn of the lateral ventricle: A case report
Intraventricular mucin‐producing glioblastoma arising in the septum pellucidum at the frontal horn of the lateral ventricle: A case report
Glioblastoma (GBM) most commonly appears to be intraparenchymal tumor, and intraventricular GBMs are rarely reported. In p...
Calcifying pseudoneoplasms of the neuraxis (CAPNON). A case report
Calcifying pseudoneoplasms of the neuraxis (CAPNON). A case report
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, slow-growing, benign lesions occurring throughout the neuroa...
The hot cross bun sign in corticobasal degeneration
The hot cross bun sign in corticobasal degeneration
The hot cross bun (HCB) sign encompasses a cross-shaped hyperintensity area in the pons on axial T2-weighted magnetic reso...
An autopsy case report of neuronal intermediate filament inclusion disease presenting with predominantly upper motor neuron features
An autopsy case report of neuronal intermediate filament inclusion disease presenting with predominantly upper motor neuron features
We describe an autopsy case of neuronal intermediate filament inclusion disease (NIFID), a subtype of frontotemporal lobar...
A case of intracranial myxoid mesenchymal tumor with EWSR1:CREM fusion in an adult female: Extensive immunohistochemical evaluation
A case of intracranial myxoid mesenchymal tumor with EWSR1:CREM fusion in an adult female: Extensive immunohistochemical evaluation
Intracranial myxoid mesenchymal tumor (IMMT) is a recently described, extremely rare group of neoplasms characterized by f...
Intracranial myxoid angiomatoid fibrous histiocytoma with “classic” histology and EWSR1:CREM fusion providing insight for reconciliation with intracranial myxoid mesenchymal tumors
Intracranial myxoid angiomatoid fibrous histiocytoma with “classic” histology and EWSR1:CREM fusion providing insight for reconciliation with intracranial myxoid mesenchymal tumors
Angiomatoid fibrous histiocytoma (AFH) is an uncommon soft tissue neoplasm that can exhibit diverse morphological features...
Primary central nervous system lymphomas with massive intratumoral hemorrhage: Clinical, radiological, pathological, and molecular features of six cases
Primary central nervous system lymphomas with massive intratumoral hemorrhage: Clinical, radiological, pathological, and molecular features of six cases
Primary central nervous system lymphomas (PCNSLs) rarely exhibit intratumoral hemorrhage. The differential diagnosis of he...
Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus
Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease; transactivation response DNA-binding prote...
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