SCI Abstract

search
Newly diagnosed multiple myeloma with bleeding and coagulation abnormalities caused by a thrombin-inhibiting substance
Newly diagnosed multiple myeloma with bleeding and coagulation abnormalities caused by a thrombin-inhibiting substance
Approximately 7% of patients with newly diagnosed multiple myeloma (MM) experience bleeding complications with varying cau...
Adult-onset severe paroxysmal cold hemoglobinuria after COVID-19 successfully treated with sutimlimab
Adult-onset severe paroxysmal cold hemoglobinuria after COVID-19 successfully treated with sutimlimab
Paroxysmal cold hemoglobinuria (PCH) is a form of cold autoimmune hemolytic anemia characterized by the presence of the Do...
Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag
Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag
Romiplostim, a thrombopoietin (TPO) receptor agonist, is a clinically approved drug that is clearly effective in reconstit...
Pathological landscape of tumor flare reaction to epcoritamab treatment
Pathological landscape of tumor flare reaction to epcoritamab treatment
Tumor flare reaction (TFR) is characterized by an increase in lesion size during immune-based therapy, often resembling di...
Precision medicine in AML: overcoming resistance
Precision medicine in AML: overcoming resistance
The development of molecularly targeted therapy for acute myeloid leukemia is progressing at an accelerated pace. Therapie...
Efficacy and safety of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A
Efficacy and safety of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A
Acquired hemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies inhibiting human factor VIII (hFVIII). Th...
CAR-T cell therapy in AML: recent progress and future perspectives
CAR-T cell therapy in AML: recent progress and future perspectives
Despite several small-molecule drugs that have revolutionized the current treatment strategy for acute myeloid leukemia (A...
Bilateral development of biclonal ocular adnexal marginal zone lymphoma at a 2-year interval
Bilateral development of biclonal ocular adnexal marginal zone lymphoma at a 2-year interval
Ocular adnexal marginal zone B-cell lymphoma (OAMZL) of the mucosa-associated lymphoid tissue is a distinct subtype of B-c...
Detection of factor XIII inhibitors in 33 patients with autoimmune factor XIII deficiency in Japan
Detection of factor XIII inhibitors in 33 patients with autoimmune factor XIII deficiency in Japan
Autoimmune factor XIII (FXIII) deficiency (AiF13D) is a rare hemorrhagic disease. The anti-FXIII autoantibodies that cause...
Molecular pathophysiology of germline mutations in acute myeloid leukemia
Molecular pathophysiology of germline mutations in acute myeloid leukemia
Germline (GL) predisposition to acute myeloid leukemia (AML) has been established as an independent disease entity in the ...
Metabolic dependencies of acute myeloid leukemia stem cells
Metabolic dependencies of acute myeloid leukemia stem cells
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy primarily driven by an immature population of AML c...
Clinical impact of airflow obstruction after allogeneic hematopoietic stem cell transplantation
Clinical impact of airflow obstruction after allogeneic hematopoietic stem cell transplantation
Criteria for airflow obstruction (AFO) at one year after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in...
Platelet and large platelet ratios are useful in predicting severity of COVID-19
Platelet and large platelet ratios are useful in predicting severity of COVID-19
The role of platelets in coronavirus disease (COVID-19) severity requires further exploration. To determine whether the pl...
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid
Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid
As multiple myeloma (MM) progresses, immune effector cells decrease in number and function and become exhausted. This rema...
Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Guidelines recommend rasburicase for high-risk patients to prevent tumor lysis syndrome (TLS). However, little information...
Optimizing random skin biopsies: a review of techniques and indications for intravascular large B-cell lymphoma
Optimizing random skin biopsies: a review of techniques and indications for intravascular large B-cell lymphoma
Intravascular large B-cell lymphoma (IVLBCL), a rare subtype of malignant lymphoma, is diagnosed by observation of intrava...
Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome
Sustained remission after cord blood transplantation for breast cancer with lung metastases and myelodysplastic syndrome
Allogenic hematopoietic stem cell transplantation (allo-HSCT) is not a standard therapy for solid cancer because of its hi...