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Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic Syndrome
Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic Syndrome
Patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) often receive antibacterial prophylaxis. Ant...
Prediction of Splenectomy Outcomes in Relapsed or Refractory Immune Thrombocytopenia
Prediction of Splenectomy Outcomes in Relapsed or Refractory Immune Thrombocytopenia
A recent publication by Kwag et al suggests that first line response to intravenous immunoglobulins in patients with immun...
CCL3 as possible negative prognostic factor in chronic lymphocytic leukemia.
CCL3 as possible negative prognostic factor in chronic lymphocytic leukemia.
Introduction: Both microenvironmental signals from surrounding cells and changes in the genome of leukemic cells play esse...
Waldenström macroglobulinemia and non-IgM-type lymphoplasmacytic lymphoma are genetically similar
Waldenström macroglobulinemia and non-IgM-type lymphoplasmacytic lymphoma are genetically similar
Introduction Waldenström macroglobulinemia (WM) represents a subset of lymphoplasmacytic lymphoma (LPL) with the imm...
The role of follicular regulatory T cells/follicular helper T cells in primary immune thrombocytopenia
The role of follicular regulatory T cells/follicular helper T cells in primary immune thrombocytopenia
Introduction Immune thrombocytopenia (ITP) is an autoimmune disease characterized by thrombocytopenia. Herein, we sought t...
Description of an institutional cohort of myeloid neoplasms carrying ETV6-locus deletions or ETV6 rearrangements
Description of an institutional cohort of myeloid neoplasms carrying ETV6-locus deletions or ETV6 rearrangements
The gene encoding for transcription factor ETV6 presents recurrent lesions in hematologic neoplasms, most notably the ETV6...
Patient-reported Outcomes in Young Adults with Myeloproliferative Neoplasms
Patient-reported Outcomes in Young Adults with Myeloproliferative Neoplasms
Introduction Genetic landscape, disease characteristics and clinical outcomes of young adults with myeloproliferative neop...
Acquired von Willebrand syndrome following a SARS-CoV2 infection
Acquired von Willebrand syndrome following a SARS-CoV2 infection
Acquired von Willebrand syndrome is a rare entity with approximately 700 cases described in the literature. Many etiologie...
Macrocytosis in Mitochondrial DNA Deletion Syndromes
Macrocytosis in Mitochondrial DNA Deletion Syndromes
Large single mtDNA (mitochondrial DNA) deletion syndrome is a rare inborn error of metabolism with variable heteroplasmy l...
Therapeutic Efficacy of Platelet Transfusion And Analysis of Influencing Factors in 364 Patients
Therapeutic Efficacy of Platelet Transfusion And Analysis of Influencing Factors in 364 Patients
Introduction: In clinical diagnosis and treatment, we found that PLT counts failed to increase significantly or even decre...
Erdheim-Chester Disease with BRAF V600E Mutation and a Concomitant Myeloid Malignancy Sharing NRAS and IDH2 Mutations
Erdheim-Chester Disease with BRAF V600E Mutation and a Concomitant Myeloid Malignancy Sharing NRAS and IDH2 Mutations
Erdheim-Chester disease (ECD) is a rare clonal histiocytic process that is characterized by a foamy (xanthomatous) prolife...
High Expression of CD300A Predicts Poor Survival in Acute Myeloid Leukemia
High Expression of CD300A Predicts Poor Survival in Acute Myeloid Leukemia
Introduction: Recent studies have suggested that CD300A was an oncogene in acute myeloid leukemia (AML) development. Howev...
A Longitudinal Assessment of the Natural Change in Haemoglobin, Haematocrit and Mean Corpuscular Volume with Age
A Longitudinal Assessment of the Natural Change in Haemoglobin, Haematocrit and Mean Corpuscular Volume with Age
Introduction: We aim to assess the natural annual trends in the levels of haemoglobin, haematocrit and mean corpuscular vo...
Two novel heterozygous mutations (p.γPhe230Val and p.AαAsn839Thr) cause hereditary hypodysfibrinogenemia in two Chinese independent families
Two novel heterozygous mutations (p.γPhe230Val and p.AαAsn839Thr) cause hereditary hypodysfibrinogenemia in two Chinese independent families
The objective of this study was to explore the molecular defects in two Chinese families with hypodysfibrinogenemia. The c...
Gene Variants in Two Families with Inherited Coagulation Factor Ⅺ Deficiency and Identification of Mutations
Gene Variants in Two Families with Inherited Coagulation Factor Ⅺ Deficiency and Identification of Mutations
Abstract Introduction: Mutations in the F11 gene can cause factor Ⅺ (FⅪ) deficiency, leading to abnormal coagulation activ...
The effectiveness of the intermediate and therapeutic doses of enoxaparin in COVID-19 patients: A comparative study of factor Xa inhibition
The effectiveness of the intermediate and therapeutic doses of enoxaparin in COVID-19 patients: A comparative study of factor Xa inhibition
Background: Management of anticoagulant therapy in COVID-19 patients is a critical role. Low Molecular Weight Heparin (LMW...
Once monthly elotuzumab, lenalidomide plus dexamethasone for multiple myeloma; a multicenter observation study
Once monthly elotuzumab, lenalidomide plus dexamethasone for multiple myeloma; a multicenter observation study
Introduction: Elotuzumab, lenalidomide plus dexamethasone (ERd) is a standard salvage chemotherapy for multiple myeloma, a...
Glomerulonephritis Secondary to Acute Promyelocytic Leukemia that Resolved after Induction Therapy.
Glomerulonephritis Secondary to Acute Promyelocytic Leukemia that Resolved after Induction Therapy.
The association of glomerulonephritis and malignant hematological disease is uncommon, but well known in chronic leukemias...