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Mixed donor chimerism following stem cell transplantation for sickle cell disease
Mixed donor chimerism following stem cell transplantation for sickle cell disease
Sickle cell disease is a debilitating hemoglobinopathy with high morbidity and mortality. Hematopoie
The invisible string of coagulation, complement, iron, and inflammation in sickle cell disease
The invisible string of coagulation, complement, iron, and inflammation in sickle cell disease
Purpose of review This review provides an update on recent advances in mechanistic studies of thr
In-vivo functions and regulation of polyphosphate in the vascular system
In-vivo functions and regulation of polyphosphate in the vascular system
Purpose of review Polyphosphate, an inorganic polymer consisting of linearly linked phosphate sub
Platelet mitochondria: the mighty few
Platelet mitochondria: the mighty few
Purpose of review Platelet mitochondrial dysfunction is both caused by, as well as a source of ox
Switching and increasing prophylaxis regimen with a genetically recombinant fusion of coagulation factor IX and albumin in haemophilia B: a case report
Switching and increasing prophylaxis regimen with a genetically recombinant fusion of coagulation factor IX and albumin in haemophilia B: a case report
Purpose of review We present a case of a boy diagnosed in 2007 with severe haemophilia B [factor
Tissue factor positive microparticles as a biomarker for increased risk of breast cancer-associated thrombosis: a mini review
Tissue factor positive microparticles as a biomarker for increased risk of breast cancer-associated thrombosis: a mini review
Purpose of review Cancer-associated thrombosis (CAT), such as venous thromboembolism (VTE), is a
The impact of prenatal inflammation on hematopoietic development
The impact of prenatal inflammation on hematopoietic development
Purpose of review Inflammation is now recognized as a major regulator of hematopoietic stem cell
Haematopoietic stem cell quiescence exposed using mitochondrial membrane potential
Haematopoietic stem cell quiescence exposed using mitochondrial membrane potential
Purpose of review Quiescence is a fundamental property of haematopoietic stem cells (HSCs). Despi
Challenges and opportunities in shared care for international patients treated with cellular therapy for nonmalignant disease
Challenges and opportunities in shared care for international patients treated with cellular therapy for nonmalignant disease
As cellular therapies gradually become the mainstay of treatment for several nonmalignant diseases,
Immunologic effects of red blood cell and platelet transfusions in neonates
Immunologic effects of red blood cell and platelet transfusions in neonates
Purpose of Review Premature neonates are frequently transfused red blood cells (RBCs) or platelet
Global perspectives on cellular therapy for children with sickle cell disease
Global perspectives on cellular therapy for children with sickle cell disease
Purpose of review Low-income and middle-income countries (LMICs), primarily in sub-Saharan Africa
Recent advances in factor XII structure and function
Recent advances in factor XII structure and function
Purpose of review Factor XII (FXII), the precursor of the protease FXIIa, contributes to patholog
Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions
Fibrin structure, viscoelasticity and lysis face the interplay of biorelevant polyions
Purpose of review In the past 5 decades, heparins have been widely used as anticoagulants in the
The protein C pathways
The protein C pathways
Purpose of review To provide an overview of the state-of-the-art in protein C (PC) pathway resear
Complement contributions to COVID-19
Complement contributions to COVID-19
Purpose of review COVID-19 remains a major source of concern, particularly as new variants emerge
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods
Purpose of review This review evaluates the different methods used to measure levels of tissue fa
No time to die? Intrinsic apoptosis signaling in hematopoietic stem and progenitor cells and therapeutic implications
No time to die? Intrinsic apoptosis signaling in hematopoietic stem and progenitor cells and therapeutic implications
Purpose of review Dysregulated apoptosis contributes to the pathogenesis of many hematologic mali
The new metabolic needs of hematopoietic stem cells
The new metabolic needs of hematopoietic stem cells
Purpose of review Hematopoietic stem cells (HSCs) are endowed with high regenerative potential to
Local and systemic features of ILC immunometabolism
Local and systemic features of ILC immunometabolism
Purpose of review Innate lymphoid cells (ILCs) are specialized immune cells that rapidly sense en
Alteration of interleukin-10-producing Type 1 regulatory cells in autoimmune diseases
Alteration of interleukin-10-producing Type 1 regulatory cells in autoimmune diseases
Purpose of review This review highlights findings describing the role of interleukin (IL)-10-prod
Clinical trials for chimeric antigen receptor T-cell therapy: lessons learned and future directions
Clinical trials for chimeric antigen receptor T-cell therapy: lessons learned and future directions
Purpose of review The purpose of this review is to summarize the status and utilization of chimer
Azacitidine maintenance in AML post induction and posttransplant
Azacitidine maintenance in AML post induction and posttransplant
Purpose of review Disease relapse remains the most common cause of death among patients with acut
Chimeric antigen receptor T-cell therapy in acute myeloid leukemia
Chimeric antigen receptor T-cell therapy in acute myeloid leukemia
Purpose of review Treatment outcome of relapsed or refractory AML patients remains dismal and new
Congenital neutropenia: disease models guiding new treatment strategies
Congenital neutropenia: disease models guiding new treatment strategies
Purpose of review Myeloid diseases are often characterized by a disturbed regulation of myeloid c
Hormetic endoplasmic reticulum stress in hematopoietic stem cells
Hormetic endoplasmic reticulum stress in hematopoietic stem cells
Purpose of review Hematopoietic stem cells (HSCs) possess the ability to regenerate over a lifeti
Recent lessons learned for ex-vivo platelet production
Recent lessons learned for ex-vivo platelet production
Purpose of review Platelet transfusion can be life-saving but carries a risk of infection or allo
Mechanisms of immunothrombosis in COVID-19
Mechanisms of immunothrombosis in COVID-19
Purpose of review Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe a
Detecting and preventing post-hematopoietic cell transplant relapse in AML
Detecting and preventing post-hematopoietic cell transplant relapse in AML
Purpose of review Relapsed disease is the primary cause of mortality for acute myeloid leukemia (
Role of chimeric antigen receptor T-cell therapy: bridge to transplantation or stand-alone therapy in pediatric acute lymphoblastic leukemia
Role of chimeric antigen receptor T-cell therapy: bridge to transplantation or stand-alone therapy in pediatric acute lymphoblastic leukemia
Purpose of review To discuss the curative potential for chimeric antigen receptor T-cell (CAR-T)
Emerging therapeutic and preventive approaches to transplant-associated thrombotic microangiopathy
Emerging therapeutic and preventive approaches to transplant-associated thrombotic microangiopathy
Purpose of review Transplant-associated thrombotic microangiopathy (TA-TMA) is a complication tha
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