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Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management
Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management
Most type 2 diabetes simulation models utilise equations mapping out lifetime trajectories of risk factors [e.g. glycated ...
Cost-of-Illness of Skin Cancer: A Systematic Review
Cost-of-Illness of Skin Cancer: A Systematic Review
Skin cancer’s rising incidence demands understanding of its economic impact. The current understanding is fragmented...
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
Quality Appraisal in Systematic Literature Reviews of Studies Eliciting Health State Utility Values: Conceptual Considerations
The increasing number of studies that generate health state utility values (HSUVs) and the impact of HSUVs on cost-utility...
Incorporating Real Option Value in Valuing Innovation: A Way Forward
Incorporating Real Option Value in Valuing Innovation: A Way Forward
Considerable progress has been made in defining and measuring the real option value (ROV) of medical technologies. However...
Estimating and Rewarding the Value of Healthcare Interventions Beyond the Healthcare Sector: A Conceptual Framework
Estimating and Rewarding the Value of Healthcare Interventions Beyond the Healthcare Sector: A Conceptual Framework
Evaluating healthcare interventions for their impacts beyond health outcomes may result in recognition of changes in human...
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Barriers and Facilitators of Using R for Decision Analytic Modeling in Health Technology Assessment: Focus Group Results
Decision models for health technology assessment (HTA) are largely submitted to HTA agencies using commercial software, wh...
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations
The current use of health economic decision models in HTA is mostly confined to single use cases, which may be inefficient...
Advances in Addressing Patient Heterogeneity in Economic Evaluation: A Review of the Methods Literature
Advances in Addressing Patient Heterogeneity in Economic Evaluation: A Review of the Methods Literature
Cost-effectiveness analyses commonly use population or sample averages, which can mask key differences across subgroups an...
Bayesian Meta-Analysis of Health State Utility Values: A Tutorial with a Practical Application in Heart Failure
Bayesian Meta-Analysis of Health State Utility Values: A Tutorial with a Practical Application in Heart Failure
Researchers incorporate health state utility values as inputs to inform economic models. However, for a particular health ...
Cost Effectiveness of Fremanezumab in Episodic and Chronic Migraine Patients from a Japanese Healthcare Perspective
Cost Effectiveness of Fremanezumab in Episodic and Chronic Migraine Patients from a Japanese Healthcare Perspective
Fremanezumab is an effective treatment for episodic (EM) and chronic migraine (CM) patients in Japan, but its cost effecti...
Cost-Effectiveness of Plasma Microbial Cell-Free DNA Sequencing When Added to Usual Care Diagnostic Testing for Immunocompromised Host Pneumonia
Cost-Effectiveness of Plasma Microbial Cell-Free DNA Sequencing When Added to Usual Care Diagnostic Testing for Immunocompromised Host Pneumonia
Immunocompromised host pneumonia (ICHP) is an important cause of morbidity and mortality, yet usual care (UC) diagnostic t...
Estimating an EQ-5D-Y-3L Value Set for Brazil
Estimating an EQ-5D-Y-3L Value Set for Brazil
The EQ-5D-Y-3L is a generic measure of health-related quality of life in children and adolescents. Although the Brazilian-...
Evaluating the Public Health and Health Economic Impacts of Baloxavir Marboxil and Oseltamivir for Influenza Pandemic Control in China: A Cost-Effectiveness Analysis Using a Linked Dynamic Transmission–Economic Evaluation Model
Evaluating the Public Health and Health Economic Impacts of Baloxavir Marboxil and Oseltamivir for Influenza Pandemic Control in China: A Cost-Effectiveness Analysis Using a Linked Dynamic Transmission–Economic Evaluation Model
Pandemic influenza poses a recurring threat to public health. Antiviral drugs are vital in combating influenza pandemics. ...
Measuring the Direct Medical Costs of Hospital-Onset Infections Using an Analogy Costing Framework
Measuring the Direct Medical Costs of Hospital-Onset Infections Using an Analogy Costing Framework
The majority of recent estimates on the direct medical cost attributable to hospital-onset infections (HOIs) has focused o...
Mixture and Non-mixture Cure Models for Health Technology Assessment: What You Need to Know
Mixture and Non-mixture Cure Models for Health Technology Assessment: What You Need to Know
There is increasing interest in the use of cure modelling to inform health technology assessment (HTA) due to the developm...
Palliative Care Costs in Different Ambulatory-Based Settings: A Systematic Review
Palliative Care Costs in Different Ambulatory-Based Settings: A Systematic Review
Cost-of-illness studies in palliative care are of growing interest in health economics. There is no standard methodology t...
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Economic Evaluations of Treatments for Duchenne Muscular Dystrophy: The Caregiver QALY Trap
Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311:1052–60.Article  ...
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Understanding Clinician Preferences for Treatment Attributes in Oncology: A Discrete Choice Experiment of Oncologists’ and Urologists’ Preferences for First-Line Treatment of Locally Advanced/Unresectable Metastatic Urothelial Carcinoma in Five European Countries
Prior discrete choice experiments (DCE) in oncology found that, on average, clinicians rank survival as the most important...
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Critical Examination of Modeling Approaches Used in Economic Evaluations of First-Line Treatments for Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: A Systematic Literature Review
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with up to 32% of patients with NSCLC harboring...
An Exploratory Analysis of the Cost-Effectiveness of a Multi-cancer Early Detection Blood Test Compared with Standard of Care Screening in Ontario, Canada
An Exploratory Analysis of the Cost-Effectiveness of a Multi-cancer Early Detection Blood Test Compared with Standard of Care Screening in Ontario, Canada
Determining whether multi-cancer early detection (MCED) tests are cost effective is important in deciding whether they sho...
The Burden of Type 2 Diabetes on the Productivity and Economy in Sub-Saharan Africa: A Life Table Modelling Analysis from a South African Perspective
The Burden of Type 2 Diabetes on the Productivity and Economy in Sub-Saharan Africa: A Life Table Modelling Analysis from a South African Perspective
The prevalence of type 2 diabetes (T2D) is rapidly increasing in Sub-Saharan Africa (SSA). T2D increases the risk of prema...
A Guide to an Iterative Approach to Model-Based Decision Making in Health and Medicine: An Iterative Decision-Making Framework
A Guide to an Iterative Approach to Model-Based Decision Making in Health and Medicine: An Iterative Decision-Making Framework
Decision makers frequently face decisions about optimal resource allocation. A model-based economic evaluation can be used...
Exploring the Cost Effectiveness of a Whole-Genome Sequencing-Based Biomarker for Treatment Selection in Patients with Advanced Lung Cancer Ineligible for Targeted Therapy
Exploring the Cost Effectiveness of a Whole-Genome Sequencing-Based Biomarker for Treatment Selection in Patients with Advanced Lung Cancer Ineligible for Targeted Therapy
We aimed to perform an early cost-effectiveness analysis of using a whole-genome sequencing-based tumor mutation burden (W...
Cost Effectiveness of Zanubrutinib Versus Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
Cost Effectiveness of Zanubrutinib Versus Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
While the efficacy and safety of zanubrutinib have been established in relapsed or refractory chronic lymphocytic leukemia...
Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review
Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review
This study aimed to systematically synthesise the cost-effectiveness of screening strategies to detect heterozygous famili...
The RETRIEVE Checklist for Studies Reporting the Elicitation of Stated Preferences for Child Health-Related Quality of Life
The RETRIEVE Checklist for Studies Reporting the Elicitation of Stated Preferences for Child Health-Related Quality of Life
Recent systematic reviews show varying methods for eliciting, modelling, and reporting preference-based values for child h...
Cost-effectiveness of Cabotegravir Long-Acting for HIV Pre-exposure Prophylaxis in the United States
Cost-effectiveness of Cabotegravir Long-Acting for HIV Pre-exposure Prophylaxis in the United States
Cabotegravir long-acting (CAB–LA) administered every 2 months was approved in the USA as pre-exposure prophylaxis (P...
A Framework for the Fair Pricing of Medicines
A Framework for the Fair Pricing of Medicines
As high-cost medicines put increasing pressure on public health care budgets, the need to identify ‘fair’ pric...
Recommendations for Emerging Good Practice and Future Research in Relation to Family and Caregiver Health Spillovers in Health Economic Evaluations: A Report of the SHEER Task Force
Recommendations for Emerging Good Practice and Future Research in Relation to Family and Caregiver Health Spillovers in Health Economic Evaluations: A Report of the SHEER Task Force
Omission of family and caregiver health spillovers from the economic evaluation of healthcare interventions remains common...
Surrogacy and the Valuation of ATMPs: Taking Our Place in the Evidence Generation/Assessment Continuum
Surrogacy and the Valuation of ATMPs: Taking Our Place in the Evidence Generation/Assessment Continuum
Medical technology is advancing rapidly, but established methods for health technology assessment are struggling to keep u...
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