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Ethical Implications of Artificial Intelligence in Vaccine Equity: Protocol for Exploring Vaccine Distribution Planning and Scheduling in Pandemics in Low- and Middle-Income Countries
Ethical Implications of Artificial Intelligence in Vaccine Equity: Protocol for Exploring Vaccine Distribution Planning and Scheduling in Pandemics in Low- and Middle-Income Countries
Background: The COVID-19 pandemic highlighted significant disparities in vaccine distribution, particularly in low- and mi...
Stress Management Among Caregivers of Detained Youth: Protocol for Randomized Controlled Trial of the RAISE Web-Based mHealth App
Stress Management Among Caregivers of Detained Youth: Protocol for Randomized Controlled Trial of the RAISE Web-Based mHealth App
Background: Detained adolescents exhibit high rates of behavioral health needs, yet few receive treatment during detention...
Digital Health Applications (DiGA) for Treating Depression and Generalized Anxiety Disorder: Protocol for a Systematic Health App Review and Systematic Review of Published Evidence
Digital Health Applications (DiGA) for Treating Depression and Generalized Anxiety Disorder: Protocol for a Systematic Health App Review and Systematic Review of Published Evidence
Background: Depression and generalized anxiety disorder (GAD) are widespread mental health diseases with significant indiv...
A Higher-Than-Standard-Intensity International Normalized Ratio Goal for Patients Undergoing Mechanical Aortic Valve Replacement With Additional Thrombotic Risk Factors: Protocol for a Systematic Review and Meta-Analysis
A Higher-Than-Standard-Intensity International Normalized Ratio Goal for Patients Undergoing Mechanical Aortic Valve Replacement With Additional Thrombotic Risk Factors: Protocol for a Systematic Review and Meta-Analysis
Background: Lifelong anticoagulation therapy with vitamin K antagonists is recommended following mechanical aortic valve r...
Conversational Systems for Social Care in Older Adults: Protocol for a Scoping Review
Conversational Systems for Social Care in Older Adults: Protocol for a Scoping Review
Background: Social care systems worldwide face increasing demographic and financial pressures. This necessitates exploring...
Interventions to Counter Health Misinformation Among Older People: Protocol for a Scoping Review
Interventions to Counter Health Misinformation Among Older People: Protocol for a Scoping Review
Background: In contemporary society, misinformation and disinformation have emerged as significant challenges, impacting v...
Integrating Lived Experience Into Medical Education Related to Children With Medical Complexity or Developmental Disabilities: Protocol for a Scoping Review
Integrating Lived Experience Into Medical Education Related to Children With Medical Complexity or Developmental Disabilities: Protocol for a Scoping Review
Background: Involving people with lived experience in medical education can benefit them, their caregivers, and medical st...
Measuring Stress Reduction in Patients Receiving Multimedia Entertainment During Vascular Surgery Under Regional Anesthesia: Protocol for a Randomized Controlled Study
Measuring Stress Reduction in Patients Receiving Multimedia Entertainment During Vascular Surgery Under Regional Anesthesia: Protocol for a Randomized Controlled Study
Background: This study explores the treatment of internal carotid artery stenosis in patients with a high risk for cardiov...
Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial
Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial
Background: More than half of the world’s population will be overweight or obese by 2035, and it is known that physical ex...
The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial
The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial
Background: Choline is an essential micronutrient crucial for fetal neurodevelopment. Numerous rodent studies reveal that ...
Wearables and Smartphones for Tracking Modifiable Risk Factors in Metabolic Health: Protocol for a Scoping Review
Wearables and Smartphones for Tracking Modifiable Risk Factors in Metabolic Health: Protocol for a Scoping Review
Background: Metabolic diseases, such as cardiovascular diseases and diabetes, contribute significantly to global mortality...
Sleep Treatment Education Program for Cancer Survivors: Protocol for an Efficacy Trial
Sleep Treatment Education Program for Cancer Survivors: Protocol for an Efficacy Trial
Background: Cancer survivors are at increased risk for chronic insomnia, even years after treatment completion. As insomni...
Tracking Implementation Outcomes of an Intensive Case Management Program for HIV: Protocol for a Mixed Methods Study
Tracking Implementation Outcomes of an Intensive Case Management Program for HIV: Protocol for a Mixed Methods Study
Background: Implementation science investigates the processes and factors that influence the successful adoption, implemen...
Assessment of Health and Well-Being Effects Associated With the Challenging Drinking Water Situation in the Gaza Strip: Protocol for a Cross-Sectional Household Survey Study
Assessment of Health and Well-Being Effects Associated With the Challenging Drinking Water Situation in the Gaza Strip: Protocol for a Cross-Sectional Household Survey Study
Background: The water supply in the Gaza Strip, Palestine, has been unstable and under strain for decades, resulting in ma...
Ultrasound-Guided High-Intensity Focused Ultrasound Combined With PD-1 Blockade in Patients With Liver Metastases From Lung Cancer: Protocol for a Single-Arm Phase 2 Trial
Ultrasound-Guided High-Intensity Focused Ultrasound Combined With PD-1 Blockade in Patients With Liver Metastases From Lung Cancer: Protocol for a Single-Arm Phase 2 Trial
Background: While immunotherapy has revolutionized oncological management, its efficacy in lung cancer patients with liver...
Understanding the Occurrence and Fate of Atmospheric Microplastics and Their Potential Risks to Human Health: Protocol for a Cross-Sectional Analysis
Understanding the Occurrence and Fate of Atmospheric Microplastics and Their Potential Risks to Human Health: Protocol for a Cross-Sectional Analysis
Background: Plastic pollution has reached an alarming magnitude, defining the contemporary era as the “Plastic Age.” Uncon...
Using Artificial Intelligence to Detect Risk of Family Violence: Protocol for a Systematic Review and Meta-Analysis
Using Artificial Intelligence to Detect Risk of Family Violence: Protocol for a Systematic Review and Meta-Analysis
Background: Despite the implementation of prevention strategies, family violence continues to be a prevalent issue worldwi...
Video Remote Sign Language Interpreting in Health Communication for Deaf People: Protocol for a Randomized Controlled Trial
Video Remote Sign Language Interpreting in Health Communication for Deaf People: Protocol for a Randomized Controlled Trial
Background: The current standard of interpretation provision is not efficacious or not acceptable to Deaf patients who com...
Development and Validation of a Novel Tool to Measure Medication Adherence for Noncommunicable Diseases in India: Protocol for an Exploratory Sequential Mixed Methods Multicentric Study
Development and Validation of a Novel Tool to Measure Medication Adherence for Noncommunicable Diseases in India: Protocol for an Exploratory Sequential Mixed Methods Multicentric Study
Background: In high-income countries, only 50% of patients treated for chronic diseases adhere to the prescribed treatment...
Consistent and Correct Use of Condoms With Lubricants and Associated Factors Among Men Who Have Sex With Men from the Ghana Men’s Study II: Protocol for a Mixed Methods Study
Consistent and Correct Use of Condoms With Lubricants and Associated Factors Among Men Who Have Sex With Men from the Ghana Men’s Study II: Protocol for a Mixed Methods Study
Background: Men who have sex with men (MSM) experience a disproportionate burden of HIV infection globally, including in G...
Improving Neurological Health in Aging Via Neuroplasticity-Based Computerized Exercise: Protocol for a Randomized Controlled Trial
Improving Neurological Health in Aging Via Neuroplasticity-Based Computerized Exercise: Protocol for a Randomized Controlled Trial
Background: Our current understanding of how computerized brain training drives cognitive and functional benefits remains ...
Protective Assets Reinforced With Integrated Care and Technology (PARITY): Protocol for a Randomized Controlled Trial
Protective Assets Reinforced With Integrated Care and Technology (PARITY): Protocol for a Randomized Controlled Trial
Background: Black women are significantly more likely to experience severe maternal morbidity and are 3 times as likely to...
An Automated Text Messaging Intervention to Reduce Substance Use Self-Stigma (Project RESTART): Protocol for a Feasibility and Acceptability Pilot Study
An Automated Text Messaging Intervention to Reduce Substance Use Self-Stigma (Project RESTART): Protocol for a Feasibility and Acceptability Pilot Study
Background: Stigma is a barrier to treatment and harm reduction seeking in people who use drugs. Most stigma reduction int...
Childhood Gender Diversity and Mental Health: Protocol for the Longitudinal, Observational Gender Journey Project
Childhood Gender Diversity and Mental Health: Protocol for the Longitudinal, Observational Gender Journey Project
Background: Prepubertal transgender, nonbinary, and gender-diverse (TGD) children (ie, those asserting gender identity, ex...
Preventing Cognitive Decline in Older Latino Adults With HIV Through a Culturally Tailored Health Promotion Intervention: Protocol for a Single-Arm Pilot Trial
Preventing Cognitive Decline in Older Latino Adults With HIV Through a Culturally Tailored Health Promotion Intervention: Protocol for a Single-Arm Pilot Trial
Background: Older Latino adults with HIV are at increased risk for mild cognitive impairment and earlier onset of aging-re...
Development of Automated Triggers in Ambulatory Settings in Brazil: Protocol for a Machine Learning–Based Design Thinking Study
Development of Automated Triggers in Ambulatory Settings in Brazil: Protocol for a Machine Learning–Based Design Thinking Study
Background: The use of technologies has had a significant impact on patient safety and the quality of care and has increas...
Ameliorating Racial Disparities in HIV Prevention via a Nurse-Led, AI-Enhanced Program for Pre-Exposure Prophylaxis Utilization Among Black Cisgender Women: Protocol for a Mixed Methods Study
Ameliorating Racial Disparities in HIV Prevention via a Nurse-Led, AI-Enhanced Program for Pre-Exposure Prophylaxis Utilization Among Black Cisgender Women: Protocol for a Mixed Methods Study
Background: HIV pre-exposure prophylaxis (PrEP) is a critical biomedical strategy to prevent HIV transmission among cisgen...
The Association Between Physical Distancing Behaviors to Avoid COVID-19 and Health-Related Quality of Life in Immunocompromised and Nonimmunocompromised Individuals: Patient-Informed Protocol for the Observational, Cross-Sectional EAGLE Study
The Association Between Physical Distancing Behaviors to Avoid COVID-19 and Health-Related Quality of Life in Immunocompromised and Nonimmunocompromised Individuals: Patient-Informed Protocol for the Observational, Cross-Sectional EAGLE Study
Background: Immunocompromised individuals are known to respond inadequately to SARS-CoV-2 vaccines, placing them at high r...
Improving the Well-Being of People With Advanced Cancer and Their Family Caregivers: Protocol for an Effectiveness-Implementation Trial of a Dyadic Digital Health Intervention (FOCUSau)
Improving the Well-Being of People With Advanced Cancer and Their Family Caregivers: Protocol for an Effectiveness-Implementation Trial of a Dyadic Digital Health Intervention (FOCUSau)
Background: Advanced cancer significantly impacts patients’ and family caregivers’ quality of life. When patients and care...
Efficacy and Safety of Shi Cervical Rotational Manipulation in Patients With Atlantoaxial Joint Subluxation: Protocol for a Randomized Controlled Trial
Efficacy and Safety of Shi Cervical Rotational Manipulation in Patients With Atlantoaxial Joint Subluxation: Protocol for a Randomized Controlled Trial
Background: The clinical diagnosis of atlantoaxial joint subluxation (AJS) in traditional Chinese medicine (TCM) is charac...
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