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The multifaceted repertoire of cellular reactive metabolites
Aye completed her undergraduate studies in chemistry at Oxford UK (2000–2004), and doctoral research in organic chemistry ...
Editorial overview: Glycobiology (2024)
Dr. Mia L Huang is a Professor in the Department of Chemistry at The Scripps Research Institute. She obtained her Ph.D. in...
Editorial: Unusual enzyme reactions in natural products biosynthesis
Taifo Mahmud received a B.S. (1989) and a professional pharmacy degree (1991) from University of North Sumatra, Indonesia,...
Editorial overview: Transforming intracellular delivery: Innovations in macromolecule transport
Jean-Philippe Pellois is a Professor in the Departments of Chemistry and Biochemistry & Biophysics at Texas A&M Un...
Recent developments in probing the levels and flux of selected organellar cations as well as organellar mechanosensitivity
Electrochemical gradients exist not only across the plasma membrane (PM) but also across membranes of organelles. Various ...
Ion transport across biological membranes
Robin S. Bon is Professor of Chemical Biology and Drug Discovery at the University of Leeds. His group uses chemical, mole...
Natural and artificial siderophores: Iron-based applications and beyond
Iron is an essential element in almost all living organisms, including bacteria, and serves as an enzymatic cofactor to ca...
Chemical tools to study and modulate glycan-mediated host-bacteria interactions
Glycans cover the surfaces of all cells, where they are poised to mediate a two-way discourse between bacteria and host ce...
Recent advances in metallophore research uncover functions in quorum sensing, antimicrobial activity, and lanthanide acquisition
Microbial metal homeostasis involves the acquisition, transport, storage, and utilization of metal ions that serve structu...
Molecular and biochemical insights from natural and engineered photosynthetic endosymbiotic systems
Eukaryogenesis was a foundational milestone in the origin of all complex life forms, including plants and mammals [1, 2, 3...
Creating and understanding new-to-nature chemistry
Virginia W. Cornish is the Helena Rubinstein Chair in the Department of Chemistry and a founding member of the Department ...
Probing ligand-induced local stability shifts: A sensitive approach to identify target proteins and binding sites at the proteomic scale
Proteins are the fundamental components of the cell and their three-dimensional structures have continuingly evolved to fi...
Recent advances in chemical proteomics for protein profiling and targeted degradation
Mass spectrometry (MS) has emerged as an indispensable tool for identifying and quantifying proteins in complex biological...
Recent advances in proximity labeling for chemical proteomics: Paving the way for in vivo applications
The integration of proximity labeling (PL) and advanced mass spectrometry-based proteomics is a robust framework for mappi...
Editorial overview: Editorial of molecular imaging
Dr. Schnermann is a Senior Investigator at the Center for Cancer Research in the National Cancer Institute, National Insti...
Chemical synthesis and biological functions of carbohydrates
Prof. You Yang obtained his Bachelor of Science in Chemistry from the University of Science and Technology of China (USTC)...
Mass spectrometry-based characterization of histone post-translational modification
In eukaryotes, the fundamental unit of chromatin is nucleosome, which contains approximately 147 base pairs of DNA wrapped...
Engineering novel adeno-associated viruses (AAVs) for improved delivery in the nervous system
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Microbial metabolite-receptor interactions in the gut microbiome
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Therapeutic synthetic anion transporters
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Drug discovery targeting Nav1.8: Structural insights and therapeutic potential
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Designing small-molecule and macromolecule sensors for imaging redox-active transition metal signaling
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Synthetic transporters for oxoanions
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Transferring enzyme features to molecular CO2 reduction catalysts
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Catalyzing the future: recent advances in chemical synthesis using enzymes
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Recent advances in the expanding genetic code
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Corrigendum to “Compounds for selective translational inhibition” [Curr Opin Chem Biol 69 (2022) 102158]
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Advances in acid-degradable and enzyme-cleavable linkers for drug delivery
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Synthetic ion channels in biomembranes
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Forty sites of TRP channel regulation
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