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Delivery of STING agonists for cancer immunotherapy
Delivery of STING agonists for cancer immunotherapy
Cancer immunotherapy aims to harness the immune system of patients to target and eliminate cancer cells. In particular, im...
The biomolecular corona of nanomedicines: effects on nanomedicine outcomes and emerging opportunities
The biomolecular corona of nanomedicines: effects on nanomedicine outcomes and emerging opportunities
Upon administration, nanomedicines adsorb a corona of endogenous biomolecules on their surface, which can affect nanomedic...
Precise control methods of the physicochemical properties of nanoparticles for personalized medicine
Precise control methods of the physicochemical properties of nanoparticles for personalized medicine
Biomedical applications of nanoparticles (NPs) have attracted much attention. With the advancement of personalized medicin...
Does the surface charge of the nanoparticles drive nanoparticle–cell membrane interactions?
Does the surface charge of the nanoparticles drive nanoparticle–cell membrane interactions?
The optimal design of nanoparticles (NPs) for biomedical applications [1], requires a critical and thorough characterizati...
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast
Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast
Natural products represent an inestimable source of valuable compounds for human health. Notably, those produced by plants...
Coupling and uncoupling growth and product formation for producing chemicals
Coupling and uncoupling growth and product formation for producing chemicals
The production of useful chemicals using micro-organisms has attracted significant attention in the pursuit of a sustainab...
Droplet-based microfluidics and enzyme evolution
Droplet-based microfluidics and enzyme evolution
Enzymes are widely used as catalysts in the chemical and pharmaceutical industries. While successful in many situations, t...
Advances in mass spectrometry-enabled multiomics at single-cell resolution
Advances in mass spectrometry-enabled multiomics at single-cell resolution
Understanding health and disease mechanisms in animals, plants, and microbes requires a systems-level investigation of reg...
Microbial synthesis of terpenoids for human nutrition — an emerging field with high business potential
Microbial synthesis of terpenoids for human nutrition — an emerging field with high business potential
Food ingredients are often derived from plant sources. Because many plant sources are becoming scarce, and are fluctuating...
Evaluating functionalities of food components by a model simulating human intestinal microbiota constructed at Kobe University
Evaluating functionalities of food components by a model simulating human intestinal microbiota constructed at Kobe University
The new coronavirus infection, the so-called covid-19, that raged around the world over the past 3 years or so has finally...
Metabolic engineering and fermentation of microorganisms for carotenoids production
Metabolic engineering and fermentation of microorganisms for carotenoids production
Carotenoids are C40 natural compounds and a unique class of terpenoids that exhibit a wide spectrum of red to yellow hues ...
Spatially structured microbial consortia and their role in food fermentations
Spatially structured microbial consortia and their role in food fermentations
Microbial consortia are important for the fermentation of foods. They bring combined functionalities to the fermented prod...
Biotechnological polyphosphate as an opportunity to contribute to the circularization of the phosphate economy
Biotechnological polyphosphate as an opportunity to contribute to the circularization of the phosphate economy
Polyphosphates, chains of polymerized phosphate subunits, are used as food additives for various applications such as cons...
Medical properties, market potential, and microbial production of golden polyketide curcumin for food, biomedical, and cosmetic applications
Medical properties, market potential, and microbial production of golden polyketide curcumin for food, biomedical, and cosmetic applications
Curcumin, a potent plant polyketide in turmeric, has gained recognition for its outstanding health benefits, including ant...
Microbial synthesis of health-promoting inositols
Microbial synthesis of health-promoting inositols
Inositol (cyclohexane-1,2,3,4,5,6-hexanol) is a group of cyclic sugar alcohols. Epimerization of the six hydroxyl groups r...
Can digital twin efforts shape microorganism-based alternative food?
Can digital twin efforts shape microorganism-based alternative food?
Food security has become a major discussion topic in recent years due to the exponential population growth, drastic climat...
Genome editing in food and agriculture: from regulations to consumer perspectives
Genome editing in food and agriculture: from regulations to consumer perspectives
Global food production and plant breeding are continuously being revolutionized through innovations in food biotechnology....
Can biotechnology lead the way toward a sustainable pharmaceutical industry?
Can biotechnology lead the way toward a sustainable pharmaceutical industry?
The impact-intensive and rapidly growing pharmaceutical industry must ensure its sustainability. This study reveals that e...
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals
Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals
The history of pharmacology is deeply intertwined with plant-derived compounds, which continue to be crucial in drug devel...
Advances in algal lipid metabolism and their use to improve oil content
Advances in algal lipid metabolism and their use to improve oil content
Microalgae, thanks to their remarkable photosynthetic activity, convert sunlight and CO2 into valuable bioproducts and ene...
Quantifying nanoparticle delivery: challenges, tools, and advances
Quantifying nanoparticle delivery: challenges, tools, and advances
Nanoparticles show great promise for drug and gene delivery applications. Nanoparticle-based carrier systems can enhance t...
Pseudomonas putida as a synthetic biology chassis and a metabolic engineering platform
Pseudomonas putida as a synthetic biology chassis and a metabolic engineering platform
The soil bacterium Pseudomonas putida, especially the KT2440 strain, is increasingly being utilized as a host for biotrans...
Editorial overview: Biotechnologies and bioinspired approaches for reducing loss and waste of foods of plant origin
Editorial overview: Biotechnologies and bioinspired approaches for reducing loss and waste of foods of plant origin
Max Teplitski is a chief science officer at the International Fresh Produce Association (IFPA), where he leads industry-wi...
Boundary flux analysis: an emerging strategy for investigating metabolic pathway activity in large cohorts
Boundary flux analysis: an emerging strategy for investigating metabolic pathway activity in large cohorts
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The posttranslational regulation of amino acid transporters is critical for their function in the tumor microenvironment
The posttranslational regulation of amino acid transporters is critical for their function in the tumor microenvironment
Volume 85, February 2024, 103022Author links open overlay panel, Amino acid transporters (AATs) facilitate nutrient uptake...
RNA-based controllers for engineering gene and cell therapies
RNA-based controllers for engineering gene and cell therapies
Over the last decade, advances in genome engineering, viral vectors, and stem cell biology have massively expanded the the...
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste
Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste
Biopolymers produced as microbial carbon storage systems, such as polyhydroxyalkanoates (PHAs), offer potential to be used...
Carbon recycling with synthetic CO2 fixation pathways
Carbon recycling with synthetic CO2 fixation pathways
Carbon fixation lies in the heart of sustainability for alleviating global climate change and supporting lives on Earth. T...
Advances in enzymatic and organismal technologies for the recycling and upcycling of petroleum-derived plastic waste
Advances in enzymatic and organismal technologies for the recycling and upcycling of petroleum-derived plastic waste
The word ‘plastics’ is an umbrella term used for hundreds of unique materials. Colloquially, plastics often refer to a sma...
Advances in promoting chimeric antigen receptor T cell trafficking and infiltration of solid tumors
Advances in promoting chimeric antigen receptor T cell trafficking and infiltration of solid tumors
Chimeric antigen receptors (CARs) are synthetic receptors that can translate extracellular binding of tumor-associated ant...
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