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Development and performance evaluation of a novel, fully automated, high-throughput GAD65 autoantibody assay on the Phadia platform
Volume 542, August 2025, 113885Author links open overlay panel, , , , , , , AbstractObjectivesIn clinics, diabetes is dete...
Characterization of antigen B subunit 2 (AgB2) gene polymorphism in sheep isolates of Echinococcus granulosus sensu lato and effect on serologic response
Echinococcus granulosus sensu lato is one of the most important zoonotic parasites causing Cystic Echinococcosis (CE) in h...
Development of multiplexed flow based assay for simultaneous identification and estimation of meningococcal capsular polysaccharide serogroups A, C, W, Y and X for conjugate vaccine manufacturing
Meningococcal meningitis is a bacterial form of meningitis caused by the gram-negative bacteria N. meningitidis. Meningiti...
Development of vectors for reformatting scFv fragments derived from phage display libraries into native IgG1 structures for in vivo imaging and therapeutic applications
The development of therapeutic monoclonal antibodies is continually expanding, and these immunotherapeutics find broad app...
Development of an ELISA strategy for the serological diagnosis of farmer's lung disease
Hypersensitivity pneumonitis (HP) is a family of interstitial lung diseases that occur in susceptible individuals followin...
Development of an enteric pathogen multiplex immunoassay to measure antibody responses in blood and saliva for integrated serology applications
Diarrhea is a major contributor to morbidity and mortality in children under five years of age, responsible for an estimat...
Development of microfluidic ELISA for measuring humoral responses to clostridial antigens in vaccinated cattle
Clostridial diseases significantly threaten livestock health, particularly in cattle, underscoring the need for effective ...
An unexpected bioanalytical challenge caused by positive control antibodies in a clinical immunogenicity assay – A simple solution and broadly applicable recommendations
Anti-drug antibody (ADA) assays are important in development of recombinant-protein therapeutic drugs. Appropriate detecti...
Development of a chimeric monoclonal antibody as a potential diagnostic reference in PR3-ANCA detection
Anti-neutrophil cytoplasmic antibodies (ANCA) are critical serological markers for ANCA-associated vasculitis (AAV), prima...
A high-throughput assay using dysfunctional T cells for phenotypic screening immune checkpoint modulators
T cells are essential components of the adaptive immune system that can recognize and eliminate pathogens or cancer cells....
An in-silico-designed multiepitope vaccine candidate can efficiently protect mice against pathogenic species of Shigella
Pathogenic species of Shigella cause a syndrome called shigellosis. Shigella flexneri (S. flexneri), Shigella boydii (S. b...
Reference intervals for functional lymphocyte proliferation studies using 3H thymidine uptake in adults
Volume 542, August 2025, 113884Author links open overlay panel, , , , , , , AbstractAimsThis study aimed to establish the ...
Indirect ELISA diagnostic based on recombinant 3AB3 nonstructural protein of foot-and-mouth disease virus for use in porcine serology
Foot-and-mouth disease (FMD) is stoutly and undeniably averred to be one of the highly contagious animal viral diseases le...
Lactococcus lactis as a delivery system for surface displayed mimotopes of major peanut allergen Ara h 2
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Peripheral blood and nasal swabs Type I and III IFNs signature in RSV positive infant with bronchiolitis
Bronchiolitis is an acute lower respiratory tract infection mainly affecting children under 24 months, primarily caused by...
Peptide-driven lateral flow platform for detection of classical swine fever viral antigen
Classical swine fever (CSF) is a highly contagious and often fatal viral disease of domestic pigs, marked by high fever, a...
Comparative assessment of a multiplex micro-chip immunoassay, VaxArray, and meso scale discovery assay for serotype-specific coronavirus IgG quantitation
Immunoassays for serology have advanced from radio-immunoassays to multiplexed micro-array-based technologies over the pas...
From phlebotomy to peripheral blood mononuclear cell isolation; effect of time and early-life HIV/ART exposure on cell yield and viability in paediatric samples in a high HIV prevalence setting
BackgroundViral infection/exposure and time from phlebotomy to peripheral blood mononuclear cell (PBMC) isolation (TPP) ma...
Development of a novel anti-PEG antibody assay enabling investigation of potential immunogenicity triggered by the PEG moiety of biotherapeutics
Polyethylene glycol (PEG) is a polyether, hydrophilic polymer derived from petroleum. PEG has a wide range of molecular we...
Development of in vitro plaque-based assay for assessment of antibody-dependent enhancement in SARS-CoV-2 infection
Antibody-dependent enhancement (ADE) of infection is a concerning phenomenon in SARS-CoV-2 infection, since it may develop...
Epitope profiling of cow's milk allergen-specific antibodies with determining IgE content in epitopes-ALL, a 14-epitopes mixture
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Isolation of anti-Ancylostoma-secreted protein 5 (ASP5) antibody from a naïve antibody phage library
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Inducing and regulating human naive CD4+ T cell proliferation by different antigen presenting cells
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Plaque reduction neutralization test for smallpox vaccines: Laboratory optimization and validation method for immunogenicity assessment
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Natural cross-reactive anti-SARS-CoV-2 antibodies in avian egg yolk
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Adaptation of the in vivo respiratory burst assay for fathead minnow larvae (Pimephales promelas)
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Characterization of an IL-8 cleavage inhibition assay to determine the functionality of anti-SpyCEP antibodies in human sera
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PD-BAT: A novel approach of pooling basophil donors for expansion of commercial laboratory testing of Chronic Spontaneous Urticaria
PD-BAT: A novel approach of pooling basophil donors for expansion of commercial laboratory testing of Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is a disorder where urticaria (hives) occurs without an identifiable provoking factor ...
An immunochromatographic test for serological diagnosis of scrub typhus
An immunochromatographic test for serological diagnosis of scrub typhus
Scrub typhus is an acute febrile human disease caused by mite vectors, which are infected by a gram negative bacterium O. ...
Performance of Softcup® menstrual cup and vulvovaginal swab samples for detection and quantification of genital cytokines
Performance of Softcup® menstrual cup and vulvovaginal swab samples for detection and quantification of genital cytokines
The field of mucosal immunology research has expanded significantly over the years and understanding biomarkers as correla...
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