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The spectrum of biopsy-proven kidney diseases, causes, and renal outcomes in acute kidney injury patients
The spectrum of biopsy-proven kidney diseases, causes, and renal outcomes in acute kidney injury patients
Abstract Introduction: Acute kidney injury (AKI) is a group of highly heterogeneous, complicated clinical syndromes. Alth...
Identification of a Splicing Variant c.3813-3A>G in NPHP3 by Reanalysis of Whole Exome Sequencing in a Chinese Boy with Nephronophthisis
Identification of a Splicing Variant c.3813-3A>G in NPHP3 by Reanalysis of Whole Exome Sequencing in a Chinese Boy with Nephronophthisis
Nephronophthisis is an autosomal recessive cystic kidney disease characterized by tubular injury and commonly results in k...
Real-World Phosphate Binder Use Among Dialysis-Dependent Patients With CKD
Real-World Phosphate Binder Use Among Dialysis-Dependent Patients With CKD
Introduction: For patients with chronic kidney disease (CKD), the need for phosphate binder (PB) treatment peaks at onset ...
A case of kidney transplantation from a deceased donor with acute kidney injury due to rhabdomyolysis
A case of kidney transplantation from a deceased donor with acute kidney injury due to rhabdomyolysis
Acute kidney injury (AKI) due to rhabdomyolysis occurs because of renal ischemia or acute tubular necrosis due to the depo...
Current status and perspectives on recurrent IgA nephropathy after kidney transplantation
Current status and perspectives on recurrent IgA nephropathy after kidney transplantation
IgA nephropathy (IgAN) is the most common form of glomerulonephritis worldwide. IgAN progresses to end-stage kidney diseas...
Significance of multinucleated polyploidization of tubular epithelial cells in kidney allografts
Significance of multinucleated polyploidization of tubular epithelial cells in kidney allografts
Introduction: Multinucleated polyploidization (MNP) of tubular epithelial cells is occasionally observed in kidney allogra...
A case of hypokalemia caused by left native renal artery stenosis in a kidney transplant recipient
A case of hypokalemia caused by left native renal artery stenosis in a kidney transplant recipient
A 39-year-old woman with end-stage renal failure of unknown origin was on peritoneal dialysis for 10 years. One year ago, ...
Challenges Posed by the Banff Classification: Diagnosis and Treatment of Chronic active T-cell mediated Rejection
Challenges Posed by the Banff Classification: Diagnosis and Treatment of Chronic active T-cell mediated Rejection
The three primary sites of acute T-cell mediated rejection (TCMR) in transplanted kidneys are the tubular epithelial cells...
Identification of a splicing variant c.3813-3A>G in NPHP3 by reanalysis of whole exome sequencing in a Chinese boy with nephronophthisis
Identification of a splicing variant c.3813-3A>G in NPHP3 by reanalysis of whole exome sequencing in a Chinese boy with nephronophthisis
Nephronophthisis is an autosomal recessive cystic kidney disease characterized by tubular injury and commonly results in k...
Thin Basement Membrane: An Underrated Cause of End-Stage Renal Disease
Thin Basement Membrane: An Underrated Cause of End-Stage Renal Disease
The term “thin basement membrane” (TBM) refers to a glomerular disorder characterized by diffuse uniform thinning of the g...
Bartter Syndrome-Related Variants Distribution: Brazilian Data and Its Comparison with Worldwide Cohorts
Bartter Syndrome-Related Variants Distribution: Brazilian Data and Its Comparison with Worldwide Cohorts
<b><i>Background:</i></b> Genetic testing is recommended for accurate diagnosis of Bartter syndrom...
Clinicopathological features of Gitelman syndrome with proteinuria and renal dysfunction
Clinicopathological features of Gitelman syndrome with proteinuria and renal dysfunction
Introduction. Gitelman syndrome (GS) is a rare renal tubular salt-wasting disorder. Besides kidney electrolytes loss, prot...
Light chain deposition disease recurrence in renal allograft after long-term remission
Light chain deposition disease recurrence in renal allograft after long-term remission
Light chain deposition disease (LCDD) is a rare manifestation of monoclonal gammopathy, which can lead to renal failure. W...
The clinicopathologic spectrum of membranous nephropathy with lupus-like features
The clinicopathologic spectrum of membranous nephropathy with lupus-like features
Introduction: The pathologic features of membranous lupus nephritis (MLN) are occasionally encountered in secondary membra...
CO-OCCURRENCE OF NEPHRONOPHTHISIS TYPE 1
AND ALSTRÖM SYNDROME: A CASE REPORT.
CO-OCCURRENCE OF NEPHRONOPHTHISIS TYPE 1 AND ALSTRÖM SYNDROME: A CASE REPORT.
We describe the unique case of a patient in whom two ciliopathies with autosomal recessive transmission were clinically an...
THE CARDINAL TRIAL OF BARDOXOLONE METHYL IN ALPORT SYNDROME: WHEN MARKETING INTERESTS PREVAIL OVER PATIENTS CLINICAL NEEDS
THE CARDINAL TRIAL OF BARDOXOLONE METHYL IN ALPORT SYNDROME: WHEN MARKETING INTERESTS PREVAIL OVER PATIENTS CLINICAL NEEDS
Context. Alport syndrome (AS) is a hereditary chronic kidney disease (CKD) with X-linked, autosomal and digenic patterns o...
Association between hypokalemia and albuminuria in a Japanese general population
Association between hypokalemia and albuminuria in a Japanese general population
Introduction: Hypokalemia is associated with an increased risk of chronic kidney disease (CKD) and is a risk factor for mo...
Piceatannol protects against high glucose-induced injury of renal tubular epithelial cells via regulating carbonic anhydrase 2
Piceatannol protects against high glucose-induced injury of renal tubular epithelial cells via regulating carbonic anhydrase 2
Introduction: We here evaluated the efficacy of piceatannol (PIC) in high glucose (HG)-induced injury of renal tubular epi...
Kidney Disease and Viral Infection in COVID-19: Why Are Kidney Organoid and Biopsy Studies Not in Agreement?
Kidney Disease and Viral Infection in COVID-19: Why Are Kidney Organoid and Biopsy Studies Not in Agreement?
<b><i>Context:</i></b> The clinical course of coronavirus disease-19 (COVID-19) can be complicated...
Effect of Orthostatic Hypotension on Kidney Function
Effect of Orthostatic Hypotension on Kidney Function
<b><i>Background:</i></b> The association between orthostatic hypotension (OH) and long-term chang...
A Study on the CLCN5 Gene in Iranian Patients: A Report of Novel and Recurrent Mutations
A Study on the CLCN5 Gene in Iranian Patients: A Report of Novel and Recurrent Mutations
<b><i>Introduction:</i></b> Dent’s disease is an X-linked inherited renal tubular disorder charact...
Functional characterization of renal tubular epithelial cells in optimized co-culture systems
Functional characterization of renal tubular epithelial cells in optimized co-culture systems
Background: Obtaining sufficient renal tubular epithelial cells (RTCs) and maintaining the functions of RTCs are vital for...
Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease
Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease
<b><i>Background:</i></b> Nonalcoholic fatty liver disease (NAFLD) is suggested as a risk factor f...
Proceedings of the 12th Annual UAB-UCSD O’Brien Center Symposium: Changing Paradigms in Acute Kidney Injury – From Mechanisms to Management
Proceedings of the 12th Annual UAB-UCSD O’Brien Center Symposium: Changing Paradigms in Acute Kidney Injury – From Mechanisms to Management
Acute kidney injury (AKI) is a significant clinical problem which can occur within hours or up to a few days and consists ...