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Efficacy and safety of SGLT2 inhibitors in nondiabetic patients with CKD: a review of recent evidence
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) were initially developed as glucose-lowering agents in pati...
Kidney Diseases
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Strategies to improve long-term outcomes for patients with chronic kidney disease in China
Background: Chronic kidney disease (CKD) is an incurable disease requiring lifelong management. China has a high prevalenc...
Kidney Diseases
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Kidney Involvement in Autoinflammatory Diseases
<b><i>Background:</i></b> Autoinflammatory diseases (AIDs) were first proposed 20 years ago and ca...
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From physiology to pathology: the role of mitochondria in acute kidney injuries and chronic kidney diseases
Background: Renal diseases remain an increasing public health issue affecting millions of people. The kidney is a highly e...
Kidney Diseases
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Therapeutic potential targeting podocyte mitochondrial dysfunction in focal segmental glomerulosclerosis
Background:Podocytes are essential components of the glomerular filtration barrier and essential for the proper filtration...
Kidney Diseases
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Develop and Validate a Risk Score in Predicting Renal Failure in Focal Segmental Glomerulosclerosis
Introduction The aim of this study is to develop and validate a risk score for end stage kidney disease (ESKD) in patients...
Kidney Diseases
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Role of IL-6 family cytokines in organ fibrosis
Background: Organ fibrosis remains an important cause of high incidence rate and mortality worldwide. The prominent role o...
Kidney Diseases
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Hospitalizations of chronic dialysis patients: a national study in China
Background Patients receiving chronic dialysis are usually with multiple comorbidities and at high-risk for hospitalizatio...
Kidney Diseases
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Nephropathy is aggravated by fatty acids in diabetic kidney disease through tubular epithelial cell necroptosis and is alleviated by an RIPK-1 inhibitor
Introduction: Diabetic kidney disease (DKD), one of the leading causes of end-stage renal disease, has complex pathogenic ...
Kidney Diseases
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A panoramic view of ferroptosis in cardiovascular disease
Background: Cardiovascular disease (CVD) remains the leading cause of disease burden worldwide. Ferroptosis, an iron-depen...
Kidney Diseases
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Impact of Angiopoietin-2 on Kidney Diseases
<b><i>Background:</i></b> Angiopoietins (Ang) are essential angiogenic factors involved in angioge...
Kidney Diseases
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Clinical Outcomes in Patients on Hemodialysis with Congestive Heart Failure
Introduction: Congestive heart failure (CHF) is one of the common complications in patients with end-stage kidney disease....
Kidney Diseases
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Renal involvement in autoinflammatory diseases
Background: Autoinflammatory diseases (AIDs) were first proposed 20 years ago and caused by dysregulation of the innate im...
Kidney Diseases
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Exosomes in Diabetic Kidney Disease
Background: Diabetic kidney disease (DKD) is a major complication of diabetes mellitus and a common cause of end-stage kid...
Kidney Diseases
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Efficacy and safety of belimumab in lupus nephritis patients: a real-world observational study in China
BACKGROUND: This study aimed to describe disease activity, clinical outcome and overall patterns of lupus nephritis care i...
Kidney Diseases
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Defining biventricular abnormalities by cardiac magnetic resonance in pre-dialysis patients with chronic kidney disease
Introduction: To investigate biventricular structural and functional abnormalities in pre-dialysis patients across stages ...
Kidney Diseases
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Evaluation of Therapies for Secondary Hyperparathyroidism Associated with Vitamin D Insufficiency in Chronic Kidney Disease
Abstract Introduction: Parathyroid hormone-lowering responses after administration of three different therapies capable o...
Kidney Diseases
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IL-37 Ameliorates Renal Fibrosis by Restoring CPT1A Mediated Fatty Acid Oxidation in Diabetic Kidney Disease
Introduction: Diabetic kidney disease (DKD) is a major source of chronic kidney disease (CKD) and end-stage renal disease ...
Kidney Diseases
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Clinical characteristics and management of patients with secondary hyperparathyroidism undergoing hemodialysis: a feasibility analysis of electronic health records using Natural Language Processing
Introduction: This study aimed to assess the feasibility of applying Natural Language Processing (NLP) to analyze real-wor...
Kidney Diseases
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Impact of Weight Gain on the Subsequent Survival of New Peritoneal Dialysis Patients
Introduction: Obesity at the initiation of dialysis was reported to adversely affect the clinical outcome of peritoneal di...
Kidney Diseases
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Intra-Brain and Plasma Levels of L-Serine Are Associated with Cognitive Status in Patients with Chronic Kidney Disease
<b><i>Introduction:</i></b> The number of patients with chronic kidney disease (CKD) is increasing...
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