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Reply to: Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups
We thank Giannini et al.1 for their response (Giannini, M. et al. Current classification criteria und...
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Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups
We read with great interest the Review article by Khoo et al. (Epidemiology of the idiopathic inflamm...
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Low-frequency and rare genetic variants associated with rheumatoid arthritis risk
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Author Correction: International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative
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Author Correction: Proposals for the rheumatological use of JAK inhibitors
Authors and AffiliationsUniversity della Campania, Department of Precision Medicine, Naples, ItalyFrancesco CicciaUniversi...
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Time for a new approach to drug development for rare systemic autoinflammatory diseases
Despite the transformative potential of treatments for systemic autoinflammatory diseases, these conditions remain underfu...
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Author Correction: Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
Author notesThese authors contributed equally: Christian Jorgensen, Danièle Noël.Authors and AffiliationsIRMB, University ...
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Biological and clinical roles of IL-18 in inflammatory diseases
Several new discoveries have revived interest in the pathogenic potential and possible clinical roles of IL-18. IL-18 is a...
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Nanohybrid therapy hits multiple arthritis targets
A novel combination of ceria nanoparticles and mesenchymal stem cell nanovesicles modified both inflammation and autoimmun...
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Shifting the SLE management paradigm: challenges and implications
Newly published European guidelines for the management of systemic lupus erythematosus (SLE) and lupus nephritis, specific...
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Primary care rheumatology: towards sustainable development in health
Globally, rheumatic musculoskeletal diseases constitute the most common causes of disability, related morbidity and econom...
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Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress
Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM) is a subtype of derm...
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Profiling joint tissues at single-cell resolution: advances and insights
Advances in the profiling of human joint tissues at single-cell resolution have provided unique insights into the organiza...
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Targeted NOD2 sequencing uncovers JIA misdiagnosis
New findings support the use of targeted next-generation sequencing of NOD2 to reassess the diagnosis of juvenile idiopath...
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Single-cell atlas unveils the diversity of RA synovial tissue
Researchers have conducted a comprehensive single-cell analysis of synovial tissue in rheumatoid arthritis, providing insi...
Nature Reviews Rheumatology
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Multi-omics reveals distinct MPA subtypes
Using multi-omics analyses, researchers have identified two distinct immunological phenotypes of microscopic polyangiitis,...
Nature Reviews Rheumatology
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l-arginine inhibits arthritis and bone loss by reprogramming osteoclast metabolism
New research shows that the amino acid l-arginine ameliorates arthritis and inhibits inflammatory bone loss by altering en...
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Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis
Since the original description of spondyloarthritis 50 years ago, results have demonstrated similarities and differences b...
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25 years of biologic DMARDs in rheumatology
2023 marks 25 years since the approval of the first biologic drug in rheumatology. In this Viewpoint, five rheumatology re...
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Immune mechanisms of depression in rheumatoid arthritis
Depression is a common and disabling comorbidity in rheumatoid arthritis that not only decreases the likelihood of remissi...
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Systemic sclerosis interstitial lung disease: unmet needs and potential solutions
Systemic sclerosis (SSc), or scleroderma, is a rare, complex, systemic autoimmune disease of unknown aetiology, characteri...
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Treatment of systemic juvenile idiopathic arthritis
Systemic juvenile idiopathic arthritis (sJIA) is an inflammatory disease with hallmarks of severe systemic inflammation, w...
Nature Reviews Rheumatology
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International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative
Adult-onset idiopathic inflammatory myopathy (IIM) is associated with an increased cancer risk within the 3 years precedin...
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Methotrexate improves pain in hand OA
Methotrexate reduces pain and stiffness in hand osteoarthritis with synovitis, according to the results of a new randomize...
Nature Reviews Rheumatology
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Are TNF inhibitors still the agent of choice for RA?
Since entering the clinic 25 years ago, biologic TNF inhibitors have transformed the outlook for people with rheumatoid ar...
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Epidemiology of the idiopathic inflammatory myopathies
The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases that affect the sk...
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Rheumatoid arthritis prevention in arthralgia: fantasy or reality?
The concept of a ‘window of opportunity’ in treating a disease assumes the existence of a time frame during wh...
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Pre-exposure prophylaxis reduces risk of COVID-19
In an observational study, SARS-CoV-2 antibody therapy used as pre-exposure prophylaxis reduced the incidence of COVID-19 ...
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FGF signalling implicated in relapsing RA
New research shows that the FGF10–FGFR1 axis is highly activated in lining fibroblast-like synoviocytes during relap...
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