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SCI Abstract
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RECOMMENDED
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Real-World-Evidence of Digital Health Applications (DiGAs) in Rheumatology: Insights from the DiGAReal Registry
Prescribable digital health applications (DiGAs) present scalable solutions to improve patient self-management in rheumato...
Rheumatology And Therapy
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Effect of Ozoralizumab Administration with or without Methotrexate in Patients with Rheumatoid Arthritis: A Post-Hoc Analysis
Ozoralizumab (OZR) is a novel tumor necrosis factor (TNF) inhibitor that was launched in Japan for treating patients with ...
Rheumatology And Therapy
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials
We assessed tofacitinib efficacy and safety in ankylosing spondylitis (AS) by body mass index (BMI) category. Data were po...
Rheumatology And Therapy
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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial
Fatigue is a key symptom in patients with ankylosing spondylitis (AS). The objective of this analysis was to esti...
Rheumatology And Therapy
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Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue
Current literature regarding cancer risk in rheumatic and musculoskeletal diseases (RMDs) is particularly poor and controv...
Rheumatology And Therapy
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The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib
While modern treatments can prevent progressive bone destruction in patients with rheumatoid arthritis (RA) achieving clin...
Rheumatology And Therapy
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Association Between Patient-Reported Pain and Remission or Low Disease Activity in Patients with Rheumatoid Arthritis: Data from RA-BE-REAL Prospective Observational Study
We aim to assess the association of patient-reported pain and remission or low disease activity (LDA) at 3 months...
Rheumatology And Therapy
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Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis
Inflammatory bowel disease (IBD) related arthritis is the most prevalent extraintestinal manifestation (EIM) of IBD, rangi...
Rheumatology And Therapy
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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis
Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (o...
Rheumatology And Therapy
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Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry
Interim analysis of the long-term safety and effectiveness of canakinumab, at a patient level, in the mevalonate kinase de...
Rheumatology And Therapy
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Real-World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis
This study sought to describe treatment patterns, persistence, and effectiveness of upadacitinib (UPA) alone and compared ...
Rheumatology And Therapy
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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial
Lorecivivint (LOR), a CDC-like kinase/dual-specificity tyrosine kinase (CLK/DYRK) inhibitor thought to modulate inflammato...
Rheumatology And Therapy
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Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis
It is important to understand the differences in patient–physician perceptions and factors affecting satisfaction wi...
Rheumatology And Therapy
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Real-World Osteoporosis Treatment Gap and Costs in Spain: Data from Women with a First Fragility Fracture or Diagnosis of Postmenopausal Osteoporosis
Postmenopausal osteoporosis (PMO) increases the risk of fragility fractures (FF), leading to disability, higher mortality,...
Rheumatology And Therapy
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Clinical Validation and Outcome Measures From Bend Ease: A Novel, Sensor-Based Digital Measurement Tool for Assessing At-Home Morning Stiffness and Spinal Range of Motion in Axial Spondyloarthritis
To evaluate the accuracy, reliability, and usability of Bend Ease, a novel smartphone-based digital health technology (DHT...
Rheumatology And Therapy
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Filling the “GAP” in Real-World Assessment of Psoriatic Arthritis Disease Activity: Performance Characteristics of a Global/Pain Composite Endpoint
Some retrospective data sources, such as electronic health records in the USA, report composite outcome measures not fully...
Rheumatology And Therapy
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Safety and Efficacy of Upadacitinib in Patients with Rheumatoid Arthritis Refractory to Biologic DMARDs: Results Through Week 216 from the SELECT-CHOICE Study
The safety and efficacy of upadacitinib 15 mg (UPA15) through week 216 was evaluated in patients with rh...
Rheumatology And Therapy
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Over Activation of IL-6/STAT3 Signaling Pathway in Juvenile Dermatomyositis
Juvenile dermatomyositis (JDM) is characterized by persistent non-purulent inflammation in the muscle and skin. The underl...
Rheumatology And Therapy
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Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey
We evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and p...
Rheumatology And Therapy
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Comparative Effectiveness of Bimekizumab and Risankizumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison
The relative efficacy of bimekizumab and risankizumab in patients with PsA who were biologic disease-modifying anti-rheuma...
Rheumatology And Therapy
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Treatment with Targeted Therapy in Patients with Psoriatic Arthritis and Inadequate Response to Methotrexate: Proposal for a Rational Strategy
The therapeutic arsenal for psoriatic arthritis (PsA) is gradually being expanded, but the use of these targeted treatment...
Rheumatology And Therapy
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Patient Experience with Chronic Refractory Gout and Its Impact on Health-Related Quality of Life: Literature Review and Qualitative Analysis
Patients with chronic refractory gout face a considerable burden of disease due to unexpected flares characterized by seve...
Rheumatology And Therapy
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Summary of Research: Effects of Adalimumab-adbm Versus Adalimumab Reference Product on Patient-Reported Outcomes in Rheumatoid Arthritis: Results from VOLTAIRE-RA
This Summary of Research overviews the results of a study that looked at patient-reported outcomes in the VOLTAIRE-RA tria...
Rheumatology And Therapy
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Clinical and Ultrasonographic Remission in Bio-naïve and Bio-failure Patients with Rheumatoid Arthritis at 24 Weeks of Upadacitinib Treatment: The UPARAREMUS Real-Life Study
Clinical remission is the main target in the management of patients with rheumatoid arthritis (RA). However, several autho...
Rheumatology And Therapy
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Efficacy and Safety of Biologics in Polymyalgia Rheumatica: A Retrospective Study
The study aimed to determine the efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in the ...
Rheumatology And Therapy
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Patients with High Baseline Neutrophil-to-Lymphocyte Ratio Exhibit Better Response to Filgotinib as Treatment for Rheumatoid Arthritis
High baseline neutrophil-to-lymphocyte ratio (NLR) in rheumatoid arthritis (RA) has been associated with positive response...
Rheumatology And Therapy
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Methotrexate, Tofacitinib, and Biologic Disease-Modifying Antirheumatic Drug Safety and Effectiveness Among Patients with Rheumatoid Arthritis in Japan: CorEvitas Registry Observational Study
The evolution of disease-modifying antirheumatic drugs (DMARDs) for the treatment of rheumatoid arthritis (RA) has improve...
Rheumatology And Therapy
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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance
In ORAL Surveillance, incidence rates (IRs) of major adverse cardiovascular events (MACE) and malignancies (excluding non-...
Rheumatology And Therapy
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Elevating the Standard of Care for Patients with Axial Spondyloarthritis: ‘Calls to Action’ from Rheumacensus, a Multistakeholder Pan-European Initiative
Several barriers to optimal care in axial spondyloarthritis (axSpA) exist, which is detrimental to patient outcomes. The R...
Rheumatology And Therapy
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Assessment of Patient–Physician Interactions in Psoriatic Arthritis: National Results of the ASSIST Study
An overarching principle for the management of psoriatic arthritis (PsA) is a shared decision-making process between physi...
Rheumatology And Therapy
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