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SCI Abstract
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RECOMMENDED
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Efficacy of Intravenous Immunoglobulin for Systemic Manifestations of Dermatomyositis Beyond Muscular and Cutaneous: Sub-analysis of the ProDERM Study
Muscle and skin involvement are well defined in dermatomyositis but other symptoms contribute significantly to the disease...
Rheumatology And Therapy
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Patient Profile and Outcomes Among Patients with Rheumatoid Arthritis Treated with Baricitinib Versus Other Therapies in Spain: The RA-BE-REAL Study
Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by joint inflammation and pain. Baricitinib, a ta...
Rheumatology And Therapy
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Saudi Clinical Practice Guidelines for Management of Axial Spondyloarthritis Disease
This guideline offers evidence-based recommendations for physicians and policymakers on managing axial spondyloarthritis (...
Rheumatology And Therapy
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A Real-World Comparison of Clinical Effectiveness of Upadacitinib, Tumor Necrosis Factor Inhibitors or Interleukin-17 Inhibitors in Patients with Axial Spondyloarthritis After Switching from an Initial Tumor Necrosis Factor Inhibitor Treatment
Tumor necrosis factor inhibitors (TNFi) may have insufficient efficacy in 40% of patients with axial spondyloarthritis (ax...
Rheumatology And Therapy
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Risk of Major Adverse Cardiovascular Events and Thromboembolism Events in Patients with Psoriatic Arthritis on JAK Inhibitors: A Network Meta-Analysis
Our objective was to evaluate the comparative effects of five Janus kinase inhibitors (JAKis) with ten interventions, comp...
Rheumatology And Therapy
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Treatment Strategies for Acute Exacerbation of Interstitial Lung Disease Associated with Systemic Autoimmune Rheumatic Diseases in Chinese Patients: A Scoping Review
Connective tissue disease-related interstitial lung disease (CTD-ILD) refers to a range of pulmonary complications arising...
Rheumatology And Therapy
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Guselkumab Efficacy in Biologic-Naïve Participants with Psoriatic Arthritis and Severe Disease Activity: Post Hoc Analysis of a Phase 3 Study
The aim of this study was to evaluate guselkumab efficacy through week 100 in participants with psoriatic arthrit...
Rheumatology And Therapy
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The Impact of Sex on the Pattern and Clinical Response of Early Psoriatic Arthritis: Real-life Data from the Italian Prospective SIRENA Study
Limited data are available on sex differences in the disease characteristics, burden and treatment outcomes of early psori...
Rheumatology And Therapy
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Real-World Effectiveness of Bimekizumab in Predominantly Difficult-to-Treat Patients with Psoriatic Arthritis Followed in a Combined Dermatology–Rheumatology Clinic: A 24-Week Multicenter Study
Bimekizumab (BKZ), a monoclonal antibody targeting interleukin (IL)-17A and IL-17F, has shown high efficacy in clinical tr...
Rheumatology And Therapy
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Efficacy and Safety of Firsekibart Compared to Etoricoxib for Gout Flares: A Phase 2, Multicenter, Open-label, Active-controlled, Randomized Non-inferiority Trial
Firsekibart, an anti-interleukin (IL)-1β monoclonal antibody, has demonstrated more sustained control of gout flares ...
Rheumatology And Therapy
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Patient Diagnostic Journey and Time to Diagnosis in Axial Spondyloarthritis: A Retrospective Cohort Study Using US Claims Data
The journey to axial spondyloarthritis (axSpA) diagnosis is often prolonged, and delayed diagnosis has been associated wit...
Rheumatology And Therapy
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Correction: Real‑World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis
Correction: Rheumatol Ther (2025) 12:173–202 https://doi.org/10.1007/s40744-024-00736...
Rheumatology And Therapy
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Safety of Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Axial Spondyloarthritis: Results from a Real-World Canadian Setting
This work aims to describe the risk of major adverse cardiovascular events (MACE), malignancy, and mortality in real-world...
Rheumatology And Therapy
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The Impact of Uncontrolled Gout on Healthcare Utilization and Health Outcomes for United States Veterans Affairs Patients
Gout is an inflammatory arthritis that, when uncontrolled, can lead to chronic pain, disability, increased demand for heal...
Rheumatology And Therapy
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Real-World Assessment of Systemic Disease Activity in Seropositive and Seronegative Patients with Sjögren’s Disease and Association with Patient-Reported Outcomes
Sjögren’s disease (SjD) is often characterized by the presence of anti-SSA/Ro and anti-SSB/La autoantibodies. T...
Rheumatology And Therapy
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Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 196-Week Results from the KEEPsAKE 1 and KEEPsAKE 2 Randomized Clinical Trials
The ongoing KEEPsAKE 1 and 2 (KS1; KS2) trials evaluate the efficacy and safety of risankizumab in patients with psoriatic...
Rheumatology And Therapy
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Real-World-Evidence of Digital Health Applications (DiGAs) in Rheumatology: Insights from the DiGAReal Registry
Prescribable digital health applications (DiGAs) present scalable solutions to improve patient self-management in rheumato...
Rheumatology And Therapy
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Effect of Ozoralizumab Administration with or without Methotrexate in Patients with Rheumatoid Arthritis: A Post-Hoc Analysis
Ozoralizumab (OZR) is a novel tumor necrosis factor (TNF) inhibitor that was launched in Japan for treating patients with ...
Rheumatology And Therapy
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials
We assessed tofacitinib efficacy and safety in ankylosing spondylitis (AS) by body mass index (BMI) category. Data were po...
Rheumatology And Therapy
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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial
Fatigue is a key symptom in patients with ankylosing spondylitis (AS). The objective of this analysis was to esti...
Rheumatology And Therapy
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Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue
Current literature regarding cancer risk in rheumatic and musculoskeletal diseases (RMDs) is particularly poor and controv...
Rheumatology And Therapy
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The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib
While modern treatments can prevent progressive bone destruction in patients with rheumatoid arthritis (RA) achieving clin...
Rheumatology And Therapy
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Association Between Patient-Reported Pain and Remission or Low Disease Activity in Patients with Rheumatoid Arthritis: Data from RA-BE-REAL Prospective Observational Study
We aim to assess the association of patient-reported pain and remission or low disease activity (LDA) at 3 months...
Rheumatology And Therapy
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Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis
Inflammatory bowel disease (IBD) related arthritis is the most prevalent extraintestinal manifestation (EIM) of IBD, rangi...
Rheumatology And Therapy
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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis
Gout is a progressive form of arthritis that causes significant pain and disability. Patients with treatment-refractory (o...
Rheumatology And Therapy
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Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry
Interim analysis of the long-term safety and effectiveness of canakinumab, at a patient level, in the mevalonate kinase de...
Rheumatology And Therapy
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Real-World Persistence and Effectiveness of Upadacitinib versus Other Janus Kinase Inhibitors and Tumor Necrosis Factor Inhibitors in Australian Patients with Rheumatoid Arthritis
This study sought to describe treatment patterns, persistence, and effectiveness of upadacitinib (UPA) alone and compared ...
Rheumatology And Therapy
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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial
Lorecivivint (LOR), a CDC-like kinase/dual-specificity tyrosine kinase (CLK/DYRK) inhibitor thought to modulate inflammato...
Rheumatology And Therapy
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Factors Influencing Treatment Satisfaction and Recognition Gaps Between Physicians and Patients with Systemic Sclerosis
It is important to understand the differences in patient–physician perceptions and factors affecting satisfaction wi...
Rheumatology And Therapy
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Real-World Osteoporosis Treatment Gap and Costs in Spain: Data from Women with a First Fragility Fracture or Diagnosis of Postmenopausal Osteoporosis
Postmenopausal osteoporosis (PMO) increases the risk of fragility fractures (FF), leading to disability, higher mortality,...
Rheumatology And Therapy
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