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In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells
The objective of this study was to induce the differentiation of human theca stem cells (hTSCs) into germ cell-like cells ...
Journal Of Ovarian Research
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Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a
Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for disting...
Journal Of Ovarian Research
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Identification and validation of senescence-related genes in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is an exceedingly intractable issue affecting female endocrine and reproductive health. H...
Journal Of Ovarian Research
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No evidence for a diminished ovarian reserve among patients with hypertensive disorders of pregnancy: a case control study
Existing evidence suggests a relation between cardiovascular dysfunction and diminished ovarian reserve. While it is known...
Journal Of Ovarian Research
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Association between maternal polycystic ovarian syndrome undergoing assisted reproductive technology and pregnancy complications and neonatal outcomes: a systematic review and meta-analysis
Polycystic ovarian syndrome (PCOS) is recognized as the most prevalent endocrine disorder among women of reproductive age....
Journal Of Ovarian Research
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The pregnancy and oncology outcome of fertility-sparing management for synchronous primary neoplasm of endometrium and ovary
To investigate the efficacy of fertility-preserving treatment for young women with synchronous primary neoplasm of endomet...
Journal Of Ovarian Research
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Characterization of MicroRNA expression profiles in the ovarian tissue of goats during the sexual maturity period
The ovary is an important reproductive organ in mammals, and its development directly affects the sexual maturity and repr...
Journal Of Ovarian Research
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Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer pro...
Journal Of Ovarian Research
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Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells
Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene ...
Journal Of Ovarian Research
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BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy
Clinical trials are currently exploring combinations of PARP inhibitors and immunotherapies for the treatment of ovarian c...
Journal Of Ovarian Research
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The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome
The prolactin receptor gene (PRLR) may contribute to polycystic ovarian syndrome (PCOS) since it plays important roles in ...
Journal Of Ovarian Research
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Dose inhibin B or anti-Müllerian hormone relate to precocious puberty in girls? result of a systematic review and meta-analysis
Existing studies have investigated the relationship between the levels of serum inhibin B (INHB), anti-müllerian horm...
Journal Of Ovarian Research
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Progress of the application clinical prediction model in polycystic ovary syndrome
Clinical prediction models play an important role in the field of medicine. These can help predict the probability of an i...
Journal Of Ovarian Research
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Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos
The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to ...
Journal Of Ovarian Research
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IFN-γ in ovarian tumor microenvironment upregulates HLA-E expression and predicts a poor prognosis
Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is g...
Journal Of Ovarian Research
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The effect of calorie-restriction along with thylakoid membranes of spinach on the gut-brain Axis Pathway and oxidative stress biomarkers in obese women with polycystic ovary syndrome: a Randomized, Double-blind, placebo-controlled clinical trial
Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide...
Journal Of Ovarian Research
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The long non-coding RNA NEAT1 promotes the progression of human ovarian cancer through targeting miR-214-3p and regulating angiogenesis
Angiogenesis and metastasis contributes substantially to the poor outcome of patients with ovarian cancer. We aimed to exp...
Journal Of Ovarian Research
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Correction: Effects and mechanisms of mUCMSCs on ovarian structure and function in naturally ageing C57 mice
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Journal Of Ovarian Research
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Prerequisites to improve surgical cytoreduction in FIGO stage III/IV epithelial ovarian cancer and subsequent clinical ramifications
No residual disease (CC 0) following cytoreductive surgery is pivotal for the prognosis of women with advanced stage epith...
Journal Of Ovarian Research
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Causal pathways linking polycystic ovary syndrome to distinct breast cancer subtypes through mediator factors: a multivariable mendelian randomization analysis
Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregu...
Journal Of Ovarian Research
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Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline
To study whether CAG repeat polymorphism of androgen receptor (AR) contributes to the risk of polycystic ovarian morpholog...
Journal Of Ovarian Research
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Baicalein improves the chemoresistance of ovarian cancer through regulation of CirSLC7A6
The present study aimed to investigate whether baicalein improves the sensitivity of resistant ovarian cancer cells to cis...
Journal Of Ovarian Research
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Three-dimensional architecture of granulosa cell derived from oocyte cumulus complex, revealed by FIB-SEM
The oocyte cumulus complex is mainly composed of an oocyte, the perivitelline space, zona pellucida and numerous granulosa...
Journal Of Ovarian Research
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Oxidative stress and inflammatory markers in ovarian follicular fluid of women with diminished ovarian reserve during in vitro fertilization
Follicular microenvironment has been proposed as an important factor for oocyte grown and maturation. We sought to evaluat...
Journal Of Ovarian Research
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Potential factors result in diminished ovarian reserve: a comprehensive review
The ovarian reserve is defined as the quantity of oocytes stored in the ovary or the number of oocytes that can be recruit...
Journal Of Ovarian Research
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Dehydroepiandrosterone-induced polycystic ovary syndrome mouse model requires continous treatments to maintain reproductive phenotypes
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in w...
Journal Of Ovarian Research
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Novel immune-related gene signature for risk stratification and prognosis prediction in ovarian cancer
The immune system played a multifaceted role in ovarian cancer (OC) and was a significant mediator of ovarian carcinogenes...
Journal Of Ovarian Research
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Growth hormone supplementation during ovarian stimulation in women with advanced maternal age undergoing preimplantation genetic testing for Aneuploidy
Studies have shown that supplementation with recombinant human GH (rh-GH) during ovarian stimulation (OS) may improve the ...
Journal Of Ovarian Research
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Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency
Premature ovarian insufficiency (POI) is an important cause of infertility characterized by the functional decline of the ...
Journal Of Ovarian Research
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Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer
Gynecologic cancers comprise malignancies in the female reproductive organs. Ovarian cancer ranks sixth in terms of incide...
Journal Of Ovarian Research
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