Beaujouan É, Reimondos A, Gray E, Evans A, Sobotka T. Declining realisation of reproductive intentions with age. Hum Reprod (Oxford England). 2019;34(10):1906–14.
Kearney AL, White KM. Examining the psychosocial determinants of women’s decisions to delay childbearing. Hum Reprod (Oxford England). 2016;31(8):1776–87.
Kasaven LS, Saso S, Getreu N, O’Neill H, Bracewell-Milnes T, Shakir F et al. Age-related fertility decline: is there a role for elective ovarian tissue cryopreservation? Human reproduction (Oxford, England) 2022, 37(9):1970–9.
Magnus MC, Wilcox AJ, Morken NH, Weinberg CR, Håberg SE. Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study. BMJ (Clinical Res ed). 2019;364:l869.
Mihalas BP, Pieper GH, Aboelenain M, Munro L, Srsen V, Currie CE, et al. Age-dependent loss of cohesion protection in human oocytes. Curr Biology: CB. 2024;34(1):117–e131115.
Article CAS PubMed Google Scholar
Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, et al. Chromosome errors in human eggs shape natural fertility over reproductive life span. Sci (New York NY). 2019;365(6460):1466–9.
The use of. Preimplantation genetic testing for aneuploidy (PGT-A): a committee opinion. Fertil Steril. 2018;109(3):429–36.
Neal SA, Morin SJ, Franasiak JM, Goodman LR, Juneau CR, Forman EJ, et al. Preimplantation genetic testing for aneuploidy is cost-effective, shortens treatment time, and reduces the risk of failed embryo transfer and clinical miscarriage. Fertil Steril. 2018;110(5):896–904.
Lawrenz B, Kalafat E, Ata B, Gallego RD, Melado L, Bayram A, et al. Ongoing pregnancy rates in single euploid frozen embryo transfers remain unaffected by female age: a retrospective study. Reprod Biomed Online. 2024;49(2):104074.
Article CAS PubMed Google Scholar
Cozzolino M, Capalbo A, Garcia-Velasco JA, Pellicer A, Vaiarelli A, Galliano D et al. In vitro fertilization and perinatal outcomes of patients with advanced maternal age after single frozen euploid embryo transfer: a propensity score-matched analysis of autologous and donor cycles. Fertility and sterility 2024.
Vitagliano A, Paffoni A, Viganò P. Does maternal age affect assisted reproduction technology success rates after euploid embryo transfer? A systematic review and meta-analysis. Fertil Steril. 2023;120(2):251–65.
Awadalla MS, Vestal NL, McGinnis LK, Ahmady A, Paulson RJ. Effect of age and morphology on sustained implantation rate after euploid blastocyst transfer. Reprod Biomed Online. 2021;43(3):395–403.
Medicine CAR. Expert consensus on human embryo morphological assessment: cleavage-stage embryos and blastocysts grading criteria. Chin J Reprod Contracept. 2022;42(12):1218–25.
Reig A, Franasiak J, Scott RT Jr., Seli E. The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. J Assist Reprod Genet. 2020;37(3):595–602.
Article PubMed PubMed Central Google Scholar
Irani M, Zaninovic N, Rosenwaks Z, Xu K. Does maternal age at retrieval influence the implantation potential of euploid blastocysts? Am J Obstet Gynecol. 2019;220(4):e379371–7.
Yao Y, Ye Y, Chen J, Zhang M, Cai X, Zheng C. Maternal-fetal immunity and recurrent spontaneous abortion. American journal of reproductive immunology (New York, NY: 1989) 2024, 91(5):e13859.
Qian J, Zhang N, Lin J, Wang C, Pan X, Chen L, et al. Distinct pattern of Th17/Treg cells in pregnant women with a history of unexplained recurrent spontaneous abortion. Biosci Trends. 2018;12(2):157–67.
Article CAS PubMed Google Scholar
Liu X-Y, Fan Q, Wang J, Li R, Xu Y, Guo J, et al. Higher chromosomal abnormality rate in blastocysts from young patients with idiopathic recurrent pregnancy loss. Fertil Steril. 2020;113:853–64.
Article CAS PubMed Google Scholar
Ni T, Wu Q, Zhu Y, Jiang W, Zhang Q, Li Y, et al. Comprehensive analysis of the associations between previous pregnancy failures and blastocyst aneuploidy as well as pregnancy outcomes after PGT-A. J Assist Reprod Genet. 2020;37:579–88.
Article PubMed PubMed Central Google Scholar
Zhao ST, Liu YB, Zhang Q, Ni TX, Yan JH. The impact of the number of previous miscarriages on embryo euploid rate and pregnancy outcomes in patients with unexplained recurrent pregnancy loss. Zhonghua Yi Xue Za Zhi 2023 Sep 26, 103(36):2874–80.
Goodpaster BH, Krishnaswami S, Resnick H, Kelley DE, Haggerty C, Harris TB, et al. Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care. 2003;26(2):372–9.
Trohl J, Schindler M, Buske M, de Nivelle J, Toto Nienguesso A, Navarrete Santos A. Advanced maternal age leads to changes within the insulin/IGF system and lipid metabolism in the reproductive tract and preimplantation embryo: insights from the rabbit model. Mol Hum Reprod 2023, 29(12).
Zhu XZ, Deng ZM, Dai FF, Liu H, Cheng YX. The impact of early pregnancy metabolic disorders on pregnancy outcome and the specific mechanism. Eur J Med Res. 2023;28(1):197.
Article PubMed PubMed Central Google Scholar
Azizi R, Soltani-Zangbar MS, Sheikhansari G, Pourmoghadam Z, Mehdizadeh A, Mahdipour M, et al. Metabolic syndrome mediates inflammatory and oxidative stress responses in patients with recurrent pregnancy loss. J Reprod Immunol. 2019;133:18–26.
Article CAS PubMed Google Scholar
Khalil A, Syngelaki A, Maiz N, Zinevich Y, Nicolaides KH. Maternal age and adverse pregnancy outcome: a cohort study. Ultrasound Obstet Gynecology: Official J Int Soc Ultrasound Obstet Gynecol. 2013;42(6):634–43.
Li J, Yan J, Jiang W. The role of maternal age on adverse pregnancy outcomes among primiparous women with singleton birth: a retrospective cohort study in urban areas of China. J maternal-fetal Neonatal Medicine: Official J Eur Association Perinat Med Federation Asia Ocean Perinat Soc Int Soc Perinat Obstet. 2023;36(2):2250894.
Pathare ADS, Loid M, Saare M, Gidlöf SB, Zamani Esteki M, Acharya G, et al. Endometrial receptivity in women of advanced age: an underrated factor in infertility. Hum Reprod Update. 2023;29(6):773–93.
Article CAS PubMed PubMed Central Google Scholar
Woods L, Dean W, Hemberger M, REPRODUCTIVE AGEING. Altered histone modification landscapes underpin defects in uterine stromal cell decidualization in aging females. Reproduction. 2024;168(3):e240171.
Article CAS PubMed PubMed Central Google Scholar
Zhang WY, Johal JK, Gardner RM, Bavan B, Milki AA. The impact of euploid blastocyst morphology and maternal age on pregnancy and neonatal outcomes in natural cycle frozen embryo transfers. J Assist Reprod Genet. 2022;39(3):647–54.
Article CAS PubMed PubMed Central Google Scholar
Abdala A, Elkhatib I, Bayram A, Arnanz A, El-Damen A, Melado L, et al. Day 5 vs day 6 single euploid blastocyst frozen embryo transfers: which variables do have an impact on the clinical pregnancy rates? J Assist Reprod Genet. 2022;39(2):379–88.
Article PubMed PubMed Central Google Scholar
Tiosano D, Mears JA, Buchner DA. Mitochondrial dysfunction in primary ovarian insufficiency. Endocrinology. 2019;160(10):2353–66.
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