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Effect of pemafibrate on high-density lipoprotein cholesterol levels and subspecies in a patient with cholesteryl ester transfer protein deficiency: A case report with mechanistic insights
Available online 22 July 2025Author links open overlay panel, , , , Highlights•Cholesteryl ester transfer protein (CETP) d...
Brief communication: Strong concordance of the North American Familial Chylomicronemia Syndrome Score with a positive genetic diagnosis in patients from the Balance study
BACKGROUNDPatients with familial chylomicronemia syndrome (FCS) are often misdiagnosed. A positive genetic diagnosis is co...
Self-medication to lower LDL cholesterol and to treat statin-associated muscle symptoms in patients with statin intolerance
BACKGROUNDSelf-medication with supplements or over-the-counter drugs is very frequent despite limited evidence on efficacy...
Experiences of people with elevated lipoprotein(a) and the impact on family and child screening
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein (LDL) particle additionally bound to apolipoprotein(a) [apo(a)], and i...
Performance of the FIND-FH machine learning algorithm for the identification of individuals with suspected familial hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal dominant disorder of cholesterol metabolism that results in high levels...
Choosing the Optimal Non-Statin Lipid Lowering Therapies for Statin-Intolerant Patients: A Systematic Review and Network Meta-Analysis
Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality globally, with elevated low-density lipoprote...
HDL remodelling and enrichment with apoCIII and apoE in Indigenous Australians
BACKGROUNDIndigenous Australians have an increased risk of type 2 diabetes mellitus (T2DM) and premature cardiovascular di...
Updated meta-analysis of the lipid-lowering efficacy of Obicetrapib: A comprehensive review of randomized controlled trials
BackgroundDespite standard lipid-lowering therapy, cardiovascular risk remains high in patients with hyperlipidemia. Obice...
Triglyceride-glucose index and 28-day all-cause mortality in critically ill obese patients: A commentary on methodological considerations
Available online 8 August 2025Author links open overlay panelSection snippetsData availabilityNo new data were created or ...
Enzyme Replacement Therapy in Cholesteryl Ester Storage Disease: A Case Report on Lysosomal Acid Lipase Deficiency Management
Lysosomal Acid Lipase Deficiency (LAL-D) comprises a spectrum of rare autosomal recessive lipid storage disorders, includi...
Human monocyte inflammation in patients with Lp(a) or atherosclerotic cardiovascular disease is not accompanied by changes in chromatin accessibility in circulating classical monocytes
Available online 10 August 2025Author links open overlay panel, , , , , , , , , , , Highlights•High plasma Lp(a) levels ar...
CARDIOMETABOLIC RISK IN PSEUDO-HYPERTRIGLYCERIDEMIA RESULTING FROM HYPERGLYCEROLEMIA
Background and aimsHyperglycerolemia is a rare X-linked inborn error of metabolism whose prevalence is currently unknown. ...
Extreme Lipoprotein (a) is a Cardiovascular Risk Equivalent in Heterozygous Familial Hypercholesterolemia
A.B. received research grants from Akcea, Amgen, Astra Zeneca, Fondation Leducq, Fondation Yvan Morin, Merck Frosst, and S...
Simulation model to estimate pretreatment (baseline) low-density lipoprotein cholesterol levels in people living with homozygous familial hypercholesterolemia
Available online 19 August 2025Author links open overlay panel, , , , , , , AbstractPretreatment levels of low-density lip...
Prevalence, Incidence, and Definition of Severe Hypertriglyceridemia: A Comprehensive Review and Weighted Summary
Available online 20 August 2025Author links open overlay panel, , , , , Highlights•Guidelines and studies lack consensus g...
Statin Use in ATTR Cardiac Amyloidosis: Assessing Tolerability and Drug Interaction Risks with Tafamidis
Transthyretin (ATTR) cardiac amyloidosis is a progressive infiltrative cardiomyopathy caused by the extracellular depositi...
An Indian Adapted Mediterranean Diet: A feasibility study
Archna Singh: Writing – review & editing, Writing – original draft, Supervision, Project administration, Methodology, ...
Non-HDL and LDL cholesterol, but not calculated remnant cholesterol, are associated with subclinical atherosclerosis
Available online 21 August 2025Author links open overlay panel, , , , , , , , Highlights•LDL and non-HDL were independentl...
Greater Alterations in Atherogenic Lipids and Inflammatory Markers in Women during Type 2 Diabetes Development and Risk of Coronary Heart Disease – Findings from Two Population-Based Studies
BackgroundDiabetes confers a greater risk of coronary heart disease (CHD) in women than in men, potentially due to women’s...
Erratum to “Scientific Poster Abstracts Selected for the National Lipid Association 2024 Scientific Sessions, May 30 – June 2, 2024, Las Vegas, Nevada” [Journal of Clinical Lipidology, Volume 18 (2024), Issue 4, Supplemental, July- August 2024, e485-e582]
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From the editors: Upcoming treatments for familial chylomicronemia syndrome: Agents that inhibit production of apolipoprotein CIII
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Novel 327bp Alu element Insertion in LDLR Exon 17 causes alternative splicing and Familial Hypercholesterolemia
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Impact of Cumulative Exposure to a High TG to HDL-C Ratio on Type 2 Diabetes Risk in Young Adults
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Exploring the Impact of Insurance Switching on the Cost-Effectiveness of Population Genetic Screening for Familial Hypercholesterolemia to US Payers
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Differential Coronary Heart Disease Risk Among Antihypertensive and Lipid-lowering Medication Users Versus Non-users: A Real-world Data Analysis: CHD risk in medication users
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A novel variant in the ABCA1 gene for Tangier Disease with diffuse histiocytosis of bone marrow.
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Implementation of a Guidelines-Based Lipid Reporting and Rates of Lipid Lowering Therapy Prescription
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Achilles Tendon Palpation for Diagnosis of Familial Hypercholesterolemia: The Compelling Need to Restore a Valuable Lost Art
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Ezetimibe-associated Rhabdomyolysis: A Comprehensive Assessment of the USFDA Adverse Event Reporting System Using Disproportionality Analysis, Case Reviews and Meta-analysis of Randomized Clinical Trials
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Nonlinearity of the Inverse Relationship between High-Density Lipoprotein (HDL) Cholesterol and Incident Cardiovascular Risk: Is It Time to Revisit the “HDL Hypothesis”?
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