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Avoiding aggregation of human bone marrow–derived mesenchymal stem cells stored in cell preservation solutions
Avoiding aggregation of human bone marrow–derived mesenchymal stem cells stored in cell preservation solutions
Adas G, Cukurova Z, Yasar KK, Yilmaz R, Isiksacan N, Kasapoglu P et al (2021) The systematic effect of mesenchymal stem ce...
DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy
DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy
DUSP4 is a biomarker of esophageal squamous cell carcinoma (ESCC), which is responsible for the prognosis in ESCC. However...
The effect of bta-miR-1296 on the proliferation and extracellular matrix synthesis of bovine mammary fibroblasts
The effect of bta-miR-1296 on the proliferation and extracellular matrix synthesis of bovine mammary fibroblasts
Mammary fibrosis in dairy cows is a chronic condition caused by mastitis, and can lead to serious culling of dairy cows re...
Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis
Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis
Spinal cord ischemia-reperfusion injury (SCII) ranks as the common complication after aortic surgery, usually leading to d...
CDC-like kinase 3 deficiency aggravates hypoxia-induced cardiomyocyte apoptosis through AKT signaling pathway
CDC-like kinase 3 deficiency aggravates hypoxia-induced cardiomyocyte apoptosis through AKT signaling pathway
Hypoxia-induced cardiomyocyte apoptosis is one major pathological change of acute myocardial infarction (AMI), but the und...
Human embryonic stem cells maintain their stemness in three-dimensional microenvironment
Human embryonic stem cells maintain their stemness in three-dimensional microenvironment
Abbas Y, Carnicer-Lombarte A, Gardner L, Thomas J, Brosens JJ, Moffett A, Sharkey AM, Franze K, Burton GJ, Oyen ML (2019) ...
Programmed cell death-1-modified pig developed using electroporation-mediated gene editing for in vitro fertilized zygotes
Programmed cell death-1-modified pig developed using electroporation-mediated gene editing for in vitro fertilized zygotes
Programmed cell death-1 (PD-1) is an immunoinhibitory receptor required to suppress inappropriate immune responses such as...
Ginsenoside Rg1 relieves rat intervertebral disc degeneration and inhibits IL-1β-induced nucleus pulposus cell apoptosis and inflammation via NF-κB signaling pathway
Ginsenoside Rg1 relieves rat intervertebral disc degeneration and inhibits IL-1β-induced nucleus pulposus cell apoptosis and inflammation via NF-κB signaling pathway
The study aimed to investigate the effect of ginsenoside Rg1 on intervertebral disc degeneration (IVDD) in rats and IL-1&#...
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose
Previous studies have implicated targeting Pim-1 proto-oncogene, serine/threonine kinase (PIM1) as a preventive measure ag...
In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells
In vitro generation of epidermal keratinocytes from human CD34-positive hematopoietic stem cells
The epidermis is largely composed of keratinocytes (KCs), and the proliferation and differentiation of KCs from the stratu...
The molecular mechanisms underlying the regeneration process in the earthworm, Perionyx excavatus exhibit indications of apoptosis-induced compensatory proliferation (AICP)
The molecular mechanisms underlying the regeneration process in the earthworm, Perionyx excavatus exhibit indications of apoptosis-induced compensatory proliferation (AICP)
Regeneration is a multifaceted biological phenomenon that necessitates the intricate orchestration of apoptosis, stem cell...
Ocu-miR-10a-5p promotes the chondrogenic differentiation of rabbit BMSCs by targeting BTRC-mediated Wnt/β-catenin signaling pathway
Ocu-miR-10a-5p promotes the chondrogenic differentiation of rabbit BMSCs by targeting BTRC-mediated Wnt/β-catenin signaling pathway
MicroRNAs (miRNAs) play an important role in articular cartilage damage in osteoarthritis (OA). However, the biological ro...
Influence of the storage conditions of embryo culture media on mouse development
Influence of the storage conditions of embryo culture media on mouse development
The culture of preimplantation embryos in vitro is an important method for human and mouse reproductive technology. This s...
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation
PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation
Peroxiredoxin 6 (PRDX6) is a protective biomarker associated with ferroptosis in heart failure (HF). This study investigat...
Differences between cultured astrocytes from neonatal and adult Wistar rats: focus on in vitro aging experimental models
Differences between cultured astrocytes from neonatal and adult Wistar rats: focus on in vitro aging experimental models
Astrocytes play key roles regulating brain homeostasis and accumulating evidence has suggested that glia are the first cel...
The R436Q missense mutation in WWP1 disrupts autoinhibition of its E3 ubiquitin ligase activity, leading to self-degradation and loss of function
The R436Q missense mutation in WWP1 disrupts autoinhibition of its E3 ubiquitin ligase activity, leading to self-degradation and loss of function
Muscular dystrophy in the NH-413 chicken is caused by a missense mutation in the WWP1 gene. WWP1 is a HECT-type E3 ubiquit...
Eco-friendly green synthesis of N‑pyrazole amino chitosan using PEG-400 as an anticancer agent against gastric cancer cells via inhibiting EGFR
Eco-friendly green synthesis of N‑pyrazole amino chitosan using PEG-400 as an anticancer agent against gastric cancer cells via inhibiting EGFR
The present study was conducted to develop a green process that provides access to the development of Schiff base derivati...
Influence of standard culture conditions and effect of oleoresin from the microalga Haematococcus pluvialis on splenic cells from healthy Balb/c mice — a pilot study
Influence of standard culture conditions and effect of oleoresin from the microalga Haematococcus pluvialis on splenic cells from healthy Balb/c mice — a pilot study
In this work, we used splenocytes from healthy mice to study the effects of the two most commonly used cell culture media ...
Downregulation of BUBR1 regulates the proliferation and cell cycle of breast cancer cells and increases the sensitivity of cells to cisplatin
Downregulation of BUBR1 regulates the proliferation and cell cycle of breast cancer cells and increases the sensitivity of cells to cisplatin
Breast cancer (BC) is a significant tissue for women’s health worldwide. The spindle assembly checkpoint protein fam...
Epigallocatechin gallate inhibits ovarian cancer cell growth and induces cell apoptosis via activation of FOXO3A
Epigallocatechin gallate inhibits ovarian cancer cell growth and induces cell apoptosis via activation of FOXO3A
Epigallocatechin gallate (EGCG), a bioactive component in tea, displays broad anti-cancer effects. Our study was designed ...
Myricetin ameliorates the IL-21-induced tumorigenic phenotype of adjuvant-induced arthritis FLS by modulating the choline kinase signaling cascade
Myricetin ameliorates the IL-21-induced tumorigenic phenotype of adjuvant-induced arthritis FLS by modulating the choline kinase signaling cascade
The synovial intimal lining is mainly governed by fibroblast-like synoviocytes (FLS), which portray a transformed tumor-li...
Correction: CD142 promotes trophoblast cell migration by inhibiting BCL2-related autophagic degradation of IL-8
Correction: CD142 promotes trophoblast cell migration by inhibiting BCL2-related autophagic degradation of IL-8
Authors and AffiliationsDepartment of Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical Un...
Cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol (TFM) in tadpole cell lines from North American frogs
Cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol (TFM) in tadpole cell lines from North American frogs
The common field lampricide, 3-trifluoromethyl-4-nitrophenol (TFM), is used to treat streams and creeks infested with high...
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer’s disease
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer’s disease
Nod-like receptor protein 3 (NLRP3) inflammasome, autophagy, and the aggregation of β-amyloid (Aβ) are key facto...
Vardenafil alleviates cigarette smoke-induced chronic obstructive pulmonary disease by activating autophagy via the AMPK/mTOR signalling pathway: an in vitro and in vivo study
Vardenafil alleviates cigarette smoke-induced chronic obstructive pulmonary disease by activating autophagy via the AMPK/mTOR signalling pathway: an in vitro and in vivo study
Chronic obstructive pulmonary disease (COPD) has always attracted global attention with its high prevalence, incidence rat...
Identification of highly active compounds from insecticidal plant Oroxylum indicum L. (Vent.) and the induction of apoptosis by lapachol on Sf9 cells
Identification of highly active compounds from insecticidal plant Oroxylum indicum L. (Vent.) and the induction of apoptosis by lapachol on Sf9 cells
The extraction of biopesticides from plants has become a promising field for agricultural development. To explore a high-e...
Anti-oxidative activities and anti-ferroptosis of conditioned medium from umbilical cord mesenchymal stem cells
Anti-oxidative activities and anti-ferroptosis of conditioned medium from umbilical cord mesenchymal stem cells
The therapeutic effect of MSC is closely related to its antioxidant capacity. There is no uniform standard for evaluating ...
Establishment of SLC7A11‐knockout mouse and its preliminary investigation in melanoma
Establishment of SLC7A11‐knockout mouse and its preliminary investigation in melanoma
Solute carrier family 7 member 11 (SLC7A11)/xCT is an amino acid transporter that mediates the cystine uptake and glutamat...
Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
This work aims to study the function of curculigoside in osteoporosis and explore whether DNMT1 is closely involved in ost...
Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells
Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells
Renal fibrosis is the most common manifestation of end-stage renal disease (ESRD), including di...
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