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Cultivation of primary cells derived from three organs of a striped dolphin (Stenella coeruleoalba) using a simple culture method
Cultivation of primary cells derived from three organs of a striped dolphin (Stenella coeruleoalba) using a simple culture method
Cetacean-cultured cells are a promising tool for life science research. Most cells used in cetacean research are derived f...
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Local anesthetics, such as ropivacaine (Ropi), are toxic to nerve cells. We aimed to explore the role of forkhead box O3 (...
Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway
Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway
The promotion of gut health, a pervasive problem in modern animal husbandry, positively affects organismal health, product...
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re (GS-Re) is a major saponin monomer found in Panax ginseng Meyer. It has been shown to exhibit a wide range ...
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis
SFRP1 reduces neutrophil infiltration and inhibits the Wnt/β-catenin pathway to alleviate oral submucous fibrosis
Oral submucous fibrosis (OSF) is a precancerous condition characterized by oral mucosal atrophy with fibrosis of the submu...
Protection from oxygen–glucose deprivation by neurosteroid treatment in primary neurons and oligodendrocytes
Protection from oxygen–glucose deprivation by neurosteroid treatment in primary neurons and oligodendrocytes
Preterm birth results in an increased risk of neonatal brain injury and neurobehavioural disorders. Despite the seriousnes...
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
The balance between oxidation and antioxidation is crucial for the development of embryo. It is harmful to the early embry...
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Currently, the supply of beta cells for islet transplantation in the treatment of type 1 diabetes is limited. Enteroendocr...
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Anna T, Agnieszka BZ (2021) Adipose-derived stem cells secretome and its potential application in “stem cell-free therapy....
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Vascularization is vital in bone tissue engineering, supporting development, remodeling, and regeneration. Lack of vascula...
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Drug repositioning of approved drugs offers advantages over de novo drug development for a rare type of cancer. To efficie...
Pluripotent cells derived from 50% epiboly zebrafish embryos
Pluripotent cells derived from 50% epiboly zebrafish embryos
Choorapoikayil S, Overvoorde J, Den HJ (2013) Deriving cell lines from zebrafish embryos and tumors. Zebrafish 10:316–325A...
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
This study aimed to explore the potential of using mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos) pre-treated wit...
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates o...
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
Interleukin-27 (IL-27) is a cytokine that is reported to be highly expressed in the peripheral blood of patients with pulm...
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Infantile hemangiomas (IH) are a common entity encountered by dermatologists, otolaryngologists, and other surgeons. Oral ...
Transfection, cytotoxicity, and cell cycle studies on the two newly developed and characterized humpback grouper (Cromileptes altivelis) fin cell lines
Transfection, cytotoxicity, and cell cycle studies on the two newly developed and characterized humpback grouper (Cromileptes altivelis) fin cell lines
The development and characterization of two novel humpback grouper (Cromileptes altivelis) fin cell lines are described in...
Decellularized leaf-based biomaterial supports osteogenic differentiation of dental pulp mesenchymal stem cells
Decellularized leaf-based biomaterial supports osteogenic differentiation of dental pulp mesenchymal stem cells
Decellularized tissues are an attractive scaffolds for 3D tissue engineering. Decellularized animal tissues have certain l...
Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon)
Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon)
Cervus nippon (sika deer) are widely distributed throughout eastern Asia. Deer possess a variety of antibodies against sev...
Histone H2A deubiquitinase BAP1 is essential for endothelial cell differentiation from human pluripotent stem cells
Histone H2A deubiquitinase BAP1 is essential for endothelial cell differentiation from human pluripotent stem cells
Polycomb group proteins (PcGs) add repressive post translational histone modifications such as H2AK119ub1, and histone H2A...
Isolation and characterisation of two epithelial-like cell lines from the gills of Chrysophrys auratus (Australasian snapper) and Oncorhynchus tshawytscha (Chinook salmon) and their use in aquatic toxicology
Isolation and characterisation of two epithelial-like cell lines from the gills of Chrysophrys auratus (Australasian snapper) and Oncorhynchus tshawytscha (Chinook salmon) and their use in aquatic toxicology
In vitro gill models are becoming increasingly important in aquatic toxicology, yet the fish gill invitrome is underrepres...
Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: An in vitro and in silico study
Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: An in vitro and in silico study
Combretum leprosum Mart. is a plant of the Combretaceae family, widely distributed in the Northeast region of Brazil, popu...
Vaginal irritation testing—prospects of human organotypic vaginal tissue culture models
Vaginal irritation testing—prospects of human organotypic vaginal tissue culture models
Personal lubricants intended for local or systemic delivery via the vaginal route can induce vaginal irritation, damage th...
Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: a model for neuronal and synaptic differentiation in neurodegeneration
Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: a model for neuronal and synaptic differentiation in neurodegeneration
There has been much interest in the use of cell culture models of neurones, to avoid the animal welfare and cost issues of...
Liraglutide ameliorates high glucose-induced vascular endothelial injury through TRIB3/NF-κB signaling pathway
Liraglutide ameliorates high glucose-induced vascular endothelial injury through TRIB3/NF-κB signaling pathway
As one of the most commonly used antidiabetic medications clinically, liraglutide is involved in the protection of vascula...
Avoiding aggregation of human bone marrow–derived mesenchymal stem cells stored in cell preservation solutions
Avoiding aggregation of human bone marrow–derived mesenchymal stem cells stored in cell preservation solutions
Adas G, Cukurova Z, Yasar KK, Yilmaz R, Isiksacan N, Kasapoglu P et al (2021) The systematic effect of mesenchymal stem ce...
DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy
DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy
DUSP4 is a biomarker of esophageal squamous cell carcinoma (ESCC), which is responsible for the prognosis in ESCC. However...
The effect of bta-miR-1296 on the proliferation and extracellular matrix synthesis of bovine mammary fibroblasts
The effect of bta-miR-1296 on the proliferation and extracellular matrix synthesis of bovine mammary fibroblasts
Mammary fibrosis in dairy cows is a chronic condition caused by mastitis, and can lead to serious culling of dairy cows re...
Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis
Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis
Spinal cord ischemia-reperfusion injury (SCII) ranks as the common complication after aortic surgery, usually leading to d...
CDC-like kinase 3 deficiency aggravates hypoxia-induced cardiomyocyte apoptosis through AKT signaling pathway
CDC-like kinase 3 deficiency aggravates hypoxia-induced cardiomyocyte apoptosis through AKT signaling pathway
Hypoxia-induced cardiomyocyte apoptosis is one major pathological change of acute myocardial infarction (AMI), but the und...
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