Armeni E, Paschou SA, Goulis DG, Lambrinoudaki I (2021) Hormone therapy regimens for managing the menopause and premature ovarian insufficiency. Best Pract Res Clin Endocrinol Metab 35:101561
Article PubMed CAS Google Scholar
Bae EA, Shin JE, Kim DH (2005) Metabolism of ginsenoside Re by human intestinal microflora and its estrogenic effect. Biol Pharm Bull 28:1903–1908
Article PubMed CAS Google Scholar
Berger DR, Aune ET, Centeno CJ, Steinmetz NJ (2020) Cryopreserved bone marrow aspirate concentrate as a cell source for the colony-forming unit fibroblast assay. Cytotherapy 22:486–493
Article PubMed CAS Google Scholar
Bhat S, Viswanathan P, Chandanala S (2021) Expansion and characterization of bone marrow derived human mesenchymal stromal cells in serum-free conditions. Sci Rep 11:3403
Article PubMed PubMed Central CAS Google Scholar
Bilia AR, Bergonzi MC (2020) The G115 standardized ginseng extract: an example for safety, efficacy, and quality of an herbal medicine. J Ginseng Res 44:179–193
Chan RY, Chen WF, Dong A, Guo D, Wong MS (2002) Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. J Clin Endocrinol Metab 87:3691–3695
Article PubMed CAS Google Scholar
Christensen LP (2009) Ginsenosides chemistry, biosynthesis, analysis, and potential health effects. Adv Food Nutr Res 55:1–99
Chuang SC, Chen CH, Chou YS (2020) G protein-coupled estrogen receptor mediates cell proliferation through the cAMP/PKA/CREB pathway in murine bone marrow mesenchymal stem cells. Int J Mol Sci 21:6490
Article PubMed PubMed Central CAS Google Scholar
Deng H, Sun C, Sun Y (2018) Lipid, protein, and microRNA composition within mesenchymal stem cell-derived exosomes. Cell Reprogram 20:178–186
Article PubMed CAS Google Scholar
Ferrin I, Beloqui I, Zabaleta L (2017) Isolation, culture, and expansion of mesenchymal stem cells. Methods Mol Biol 1590:177–190
Article PubMed CAS Google Scholar
Frazier TP, Gimble JM, Devay JW, Tucker HA, Chiu ES, Rowan BG (2013) Body mass index affects proliferation and osteogenic differentiation of human subcutaneous adipose tissue-derived stem cells. BMC Cell Biol 7(14):34
Friedenstein AJ, Chailakhjan RK, Lalykina KS (1970) The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 3:393–403
Furukawa T, Bai CX, Kaihara A, Ozaki E, Kawano T, Nakaya Y, Awais M, Sato M, Umezawa Y, Kurokawa J (2006) Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones. Mol Pharmacol 70:1916–1924
Article PubMed CAS Google Scholar
Gao XY, Liu GC, Zhang JX (2022) Pharmacological properties of ginsenoside Re. Front Pharmacol 13:754191
Article PubMed PubMed Central CAS Google Scholar
Gao Y, Zhu P, Xu SF (2019) Ginsenoside Re inhibits PDGF-BB-induced VSMC proliferation via the eNOS/NO/cGMP pathway. Biomed Pharmacother 115:108934
Article PubMed CAS Google Scholar
Gronthos S, Simmons PJ (1995) The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood 85:929–940
Article PubMed CAS Google Scholar
Gu Y, Zhou J, Wang Q, Fan W, Yin G (2016) Ginsenoside Rg1 promotes osteogenic differentiation of rBMSCs and healing of rat tibial fractures through regulation of GR-dependent BMP-2/SMAD signaling. Sci Rep 6:25282
Article PubMed PubMed Central CAS Google Scholar
Hade MD, Suire CN, Suo Z (2021) Mesenchymal stem cell-derived exosomes: applications in regenerative medicine. Cells 10:1959
Article PubMed PubMed Central CAS Google Scholar
Haynesworth SE, Baber MA, Caplan AI (1996) Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1 alpha. J Cell Physiol 166:585–592
Article PubMed CAS Google Scholar
He F, Yao G (2021) Ginsenoside Rg1 as a potential regulator of hematopoietic stem/progenitor cells. Stem Cells Int 2021:4633270
Article PubMed PubMed Central Google Scholar
Hong L, Zhang G, Sultana H, Yu Y, Wei Z (2011) The effects of 17-β estradiol on enhancing proliferation of human bone marrow mesenchymal stromal cells in vitro. Stem Cells Dev 20:925–931
Article PubMed CAS Google Scholar
Hong T, Kim MY, Da Ly D (2020) Ca(2+)-activated mitochondrial biogenesis and functions improve stem cell fate in Rg3-treated human mesenchymal stem cells. Stem Cell Res Ther 11:467
Article PubMed PubMed Central CAS Google Scholar
Hu W, JingWang P (2015) The positive effects of ginsenoside Rg1 upon the hematopoietic microenvironment in a D-galactose-induced aged rat model. BMC Complement Altern Med 15:119
Article PubMed PubMed Central Google Scholar
Huang YC, Chen CT, Chen SC, Lai PH, Liang HC, Chang Y, Yu LC, Sung HW (2005) A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration. Pharm Res 22:636–646
Article PubMed CAS Google Scholar
Kim YK, Yoo DS, Xu H (2009) Ginsenoside content of berries and roots of three typical Korean ginseng (Panax ginseng) cultivars. Nat Prod Commun 4:903–906
Lau WS, Chan RY, Guo DA, Wong MS (2008) Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway. J Steroid Biochem Mol Biol 108:64–71
Article PubMed CAS Google Scholar
Lavoie H, Gagnon J, Therrien M (2020) ERK signalling: a master regulator of cell behaviour, life and fate. Nat Rev Mol Cell Biol 21:607–632
Article PubMed CAS Google Scholar
Lee HW, Ang L, Lee MS (2022) Using ginseng for menopausal women’s health care: a systematic review of randomized placebo-controlled trials. Complement Ther Clin Pract 48:101615
Lee YJ, Jin YR, Lim WC, Ji SM, Cho JY, Ban JJ, Lee SK (2003) Ginsenoside Rc and Re stimulate c-fos expression in MCF-7 human breast carcinoma cells. Arch Pharm Res 26:53–57
Article PubMed CAS Google Scholar
Levy M, Crawford JR, Dib N (2019) Phase I/II study of safety and preliminary efficacy of intravenous allogeneic mesenchymal stem cells in chronic stroke. Stroke 50:2835–2841
Li Y, Charif N, Mainard D (2014) Donor’s age dependent proliferation decrease of human bone marrow mesenchymal stem cells is linked to diminished clonogenicity. Biomed Mater Eng 24:47–52
Li Y, Yan MY, Chen QC (2022) Current research on complementary and alternative medicine in the treatment of premature ovarian failure: an update review. Evid Based Complement Alternat Med 2022:2574438
Comments (0)