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A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes‐associated periodontitis by enhancing autophagy in osteoclasts.
Abstract Background and Objective Type 2 diabetes (T2D)-associated periodontitis is severe and refractory in many cases. C...
Journal Of Periodontal Research
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Herpes simplex virus type 1 in subgingival plaque and periodontal diseases. Meta‐analysis of observational studies
Abstract Background and objectives This meta-analysis of observational studies (PROSPERO registration number CRD4202123605...
Journal Of Periodontal Research
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Plasminogen gene polymorphisms [c.924C>T and IVS 8+14 G>A] in periodontitis and familial Mediterranean fever: A case‐control study
Abstract Background and objective The plasminogen (PLG) activation system plays an essential role in severe inflammation b...
Journal Of Periodontal Research
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Distribution of neutrophil and monocyte/macrophage populations induced by the CXCR4 inhibitor AMD3100 in blood and periodontal tissue early after periodontitis induction
Abstract CXCR4, a CXCL12 receptor, is expressed on epithelial cells, fibroblasts, and inflammatory cells. The CXCR4-CXCL12...
Journal Of Periodontal Research
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Wound healing in periodontal disease induces macrophage polarization characterized by different arginine‐metabolizing enzymes
Abstract Background and objective Macrophages play important roles from the initiation of inflammation to wound healing. T...
Journal Of Periodontal Research
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Abnormal hsa_circ_0003948 expression affects chronic periodontitis development by regulating miR‐144‐3p/NR2F2/PTEN signaling
Abstract Background and Objective This study aimed to investigate the correlation between chronic periodontitis (CP) and a...
Journal Of Periodontal Research
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Chemomechanical preparation influences the microbial community and the levels of LPS, LTA and cytokines in combined endodontic‐periodontal lesions: A clinical study
Abstract Background This study was conducted to compare the microbiomes, the levels of lipopolysaccharides (LPS), lipoteic...
Journal Of Periodontal Research
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LncRNA LOXL1‐AS1 inhibits proliferation of PDLSCs and downregulates IL‐1β in periodontitis patients
Abstract Background The carcinogenic role of lncRNA LOXL1-AS1 in thoracic aortic aneurysm has been confirmed, but its role...
Journal Of Periodontal Research
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Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis
Abstract Background and Objective Oral malodour is often observed in gingivitis and chronic periodontitis patients, and th...
Journal Of Periodontal Research
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Food hardness can regulate orthodontic tooth movement in mice
Abstract Background and objectives Orthodontic treatment is often accompanied with prescription of softer foods to patient...
Journal Of Periodontal Research
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The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis
Abstract Periodontopathic bacteria constantly stimulate the host, which causes an immune response, leading to host-induced...
Journal Of Periodontal Research
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Is TIMP‐1 a biomarker for periodontal disease? A systematic review and meta‐analysis
Abstract Objective One of the most important families of proteases associated with periodontal disease is the family of th...
Journal Of Periodontal Research
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Is periodontitis a risk factor of benign or malignant colorectal tumor? A population‐based cohort study
Abstract Objective To examine the risk of developing benign or malignant colorectal tumors in patients with periodontitis ...
Journal Of Periodontal Research
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Iron accumulation is associated with periodontal destruction in a mouse model of HFE‐related haemochromatosis
Abstract Objective To investigate the effect of Hfe gene mutation on the distribution of iron and periodontal bone loss in...
Journal Of Periodontal Research
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Human oral mucosa‐derived neural crest‐like stem cells differentiate into functional osteoprogenitors that contribute to regeneration of critical size calvaria defects
Abstract Background and objective Regeneration of large bony defects is an unmet medical need. The therapeutic effect of f...
Journal Of Periodontal Research
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Functional Adaptation of LPS‐affected Dentoalveolar Fibrous Joints in Rats
Abstract Introduction The functional interplay between cementum of the root and alveolar bone of the socket is tuned by a ...
Journal Of Periodontal Research
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Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies
Abstract Objectives The present systematic review examined the available evidence on distinctive salivary ion profile in p...
Journal Of Periodontal Research
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Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis
Abstract Background and Objective The abnormal structure and function of mitochondria in cells is closely associated with ...
Journal Of Periodontal Research
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Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis
Abstract Background and objective Exosomes are small vesicles secreted from many cell types. Their biological effects larg...
Journal Of Periodontal Research
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Molecular profiling of intrabony defects' gingival crevicular fluid
Abstract Aim To profile, for the first time, the gingival crevicular fluid (GCF) of intrabony defects against a wide array...
Journal Of Periodontal Research
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Altered human alveolar bone gene expression in type 2 diabetes—A cross‐sectional study
Abstract Objective The objective of this cross-sectional study is to investigate alveolar bone gene expression in health a...
Journal Of Periodontal Research
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Periodontal tissue engineering using an apatite/collagen scaffold obtained by a plasma‐ and precursor‐assisted biomimetic process
Abstract Background and objectives In the treatment of severe periodontal destruction, there is a strong demand for advanc...
Journal Of Periodontal Research
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Periodontitis and Systemic Lupus Erythematosus: A systematic review and meta‐analysis
Abstract This systematic review and meta-analysis evaluated the association between periodontitis (PD) and systemic lupus ...
Journal Of Periodontal Research
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The emerging role of small extracellular vesicles in saliva and gingival crevicular fluid as diagnostics for periodontitis
Abstract Periodontitis is a highly prevalent multifactorial chronic inflammatory disease associated with a destructive hos...
Journal Of Periodontal Research
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Differential regulation of NPY and SP receptor expression in STRO‐1+ve PDLSCs by inflammatory cytokines
Abstract Objectives The aims of this study were to investigate neuropeptide receptor expression regulation on STRO-1 +ve p...
Journal Of Periodontal Research
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Activation of GATA‐binding protein 4 regulates monocyte chemoattractant protein‐1 and chemotaxis in periodontal ligament cells
Abstract Background and Objectives Periodontitis is a chronic inflammatory disease of periodontal supporting tissues. The ...
Journal Of Periodontal Research
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In vitro evaluation of the effect of the electronic cigarette aerosol, Cannabis smoke, and conventional cigarette smoke on the properties of gingival fibroblasts/gingival mesenchymal stem cells
Abstract Objective The current study aimed to evaluate the effect of electronic cigarette (EC) aerosol, Cannabis, and conv...
Journal Of Periodontal Research
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Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss
Abstract Background and objective Clinical studies have shown that metabolic syndrome (MetS) exacerbates periodontitis. Ho...
Journal Of Periodontal Research
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Surfactin reduces particulate matter–induced VCAM‐1–dependent monocyte adhesion in human gingival fibroblasts by increasing Nrf2‐dependent HO‐1 expression
Abstract Background and objectives The mechanisms of particulate matter (PM) toxicity involve the generation of ROS and up...
Journal Of Periodontal Research
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Periodontal disease inequities among Indigenous populations: A systematic review and meta‐analysis
Abstract The prevalence of periodontal disease varies considerably between Indigenous and general populations. The aim of ...
Journal Of Periodontal Research
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