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Longitudinal tracking of circulating rare events in the liquid biopsy of stage III–IV non-small cell lung cancer patients
Longitudinal tracking of circulating rare events in the liquid biopsy of stage III–IV non-small cell lung cancer patients
In the United States, lung cancer is the second most common type of cancer with non-small cell lung cancer (NSCLC) encompa...
circ_WASF2 regulates ferroptosis by miR-634/ GPX4 signaling in pancreatic cancer
circ_WASF2 regulates ferroptosis by miR-634/ GPX4 signaling in pancreatic cancer
Pancreatic cancer (PC) is one of the most lethal malignant gastrointestinal tumors (GI) characterized by a poor prognosis....
Crosstalk between cancer cells and macrophages promotes OSCC cell migration and invasion through a CXCL1/EGF positive feedback loop
Crosstalk between cancer cells and macrophages promotes OSCC cell migration and invasion through a CXCL1/EGF positive feedback loop
C-X-C motif chemokine ligand 1 (CXCL1) and epithelial growth factor (EGF) are highly secreted by oral squamous cell carcin...
The regulation of hypoxia-related lncRNAs in hepatocellular carcinoma
The regulation of hypoxia-related lncRNAs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is still a public health disease with its high prevalence and morbidity. Short of early dia...
Pan-cancer analysis for the prognostic and immunological role of CD47: interact with TNFRSF9 inducing CD8 + T cell exhaustion
Pan-cancer analysis for the prognostic and immunological role of CD47: interact with TNFRSF9 inducing CD8 + T cell exhaustion
The research endeavors to explore the implications of CD47 in cancer immunotherapy effectiveness. Specifically, there is a...
miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression
miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression
Epithelial-mesenchymal transition (EMT) plays an important role in malignant progression of Triple-negative breast cancer ...
CXCL10 could be a prognostic and immunological biomarker in bladder cancer
CXCL10 could be a prognostic and immunological biomarker in bladder cancer
As proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in ant...
Nomogram for predicting survival in T1–T2 stage patients with supraglottic squamous cell carcinoma
Nomogram for predicting survival in T1–T2 stage patients with supraglottic squamous cell carcinoma
Supraglottic squamous cell carcinoma (SGSCC) is characterized by low differentiation, rapid growth, and inconspicuous init...
Mechanism study of lncRNA RMRP regulating esophageal squamous cell carcinoma through miR-580-3p/ATP13A3 axis
Mechanism study of lncRNA RMRP regulating esophageal squamous cell carcinoma through miR-580-3p/ATP13A3 axis
It is well-known that lncRNAs regulate energy metabolism in tumors. This study focused on the action of RMRP on esophageal...
Hsp90α and cell death in cancers: a review
Hsp90α and cell death in cancers: a review
Heat shock protein 90α (Hsp90α), an important molecular chaperone, plays a crucial role in regulating the activi...
Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomas
Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomas
Parthanatos, a cell death mechanism triggered by PARP-1 activation, is implicated in oncogenic processes, yet their role i...
Exploration of the influence of GOLGA8B on prostate cancer progression and the resistance of castration-resistant prostate cancer to cabazitaxel
Exploration of the influence of GOLGA8B on prostate cancer progression and the resistance of castration-resistant prostate cancer to cabazitaxel
Castration-resistant prostate cancer (CRPC) represents the final stage of prostate cancer (PCa). Cabazitaxel, a taxane che...
Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway
Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway
Reprogramming of the serine synthesis pathway (SSP) is intricately linked to the progression of epithelial ovarian cancer ...
Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis
Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis
Clear cell renal cell carcinoma (ccRCC), the most common pathological subtype of kidney cancer, accounts for approximately...
Identification of NINJ1 as a novel prognostic predictor for retroperitoneal liposarcoma
Identification of NINJ1 as a novel prognostic predictor for retroperitoneal liposarcoma
Retroperitoneal liposarcoma (RPLS) is known for its propensity for local recurrence and short survival time. We aimed to i...
circPDK1 competitively binds miR-4731-5p to mediate GIGYF1 expression and increase paclitaxel sensitivity in non-small cell lung cancer
circPDK1 competitively binds miR-4731-5p to mediate GIGYF1 expression and increase paclitaxel sensitivity in non-small cell lung cancer
To investigate the action of circPDK1 in paclitaxel (PTX) resistance in non-small cell lung cancer (NSCLC). circPDK1, miR-...
ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway
ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway
Clear cell renal cell carcinoma (ccRCC), with high mortality and poor prognosis, is the most common type of renal malignan...
Molecular mechanism of MLCK1 inducing 5-Fu resistance in colorectal cancer cells through activation of TNFR2/NF-κB pathway
Molecular mechanism of MLCK1 inducing 5-Fu resistance in colorectal cancer cells through activation of TNFR2/NF-κB pathway
Chemotherapy resistance in colorectal cancer have been faced with significant challenges in recent years. Particular inter...
Prognostic significance and immune landscape of a cell cycle progression-related risk model in bladder cancer
Prognostic significance and immune landscape of a cell cycle progression-related risk model in bladder cancer
A greater emphasis has been placed on the part of cell cycle progression (CCP) in cancer in recent years. Nevertheless, th...
LncRNA HOTAIR down-expression inhibits the invasion and tumorigenicity of epithelial ovarian cancer cells by suppressing TGF-β1 and ZEB1
LncRNA HOTAIR down-expression inhibits the invasion and tumorigenicity of epithelial ovarian cancer cells by suppressing TGF-β1 and ZEB1
Epithelial ovarian cancer (EOC) is a pathological type with a higher mortality rate among gynecological cancers today. Lon...
Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway
Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway
To investigate the effect of COVID-19 infection on pancreatic cancer. Based on the mRNA-Seq data of COVID-19 patients and ...
Increased PAFAH1B3 was associated with poor prognosis and T-cell exhaustion microenvironment in hepatocellular carcinoma
Increased PAFAH1B3 was associated with poor prognosis and T-cell exhaustion microenvironment in hepatocellular carcinoma
The link between T-cell exhaustion (TEX) and PAFAH1B3 in hepatocellular carcinoma (HCC) remains unknown, even though both ...
Treatment outcomes of radiotherapy with concurrent weekly cisplatin in older patients with locally advanced head and neck squamous cell carcinoma
Treatment outcomes of radiotherapy with concurrent weekly cisplatin in older patients with locally advanced head and neck squamous cell carcinoma
Tri-weekly cisplatin and radiotherapy (CDDP + RT) is a standard of care for locally advanced head and neck squ...
Using machine learning-based radiomics to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes
Using machine learning-based radiomics to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes
To establish a machine learning-based radiomics model to differentiate between glioma and solitary brain metastasis from l...
Deep-learning-based survival prediction of patients with lower limb melanoma
Deep-learning-based survival prediction of patients with lower limb melanoma
For the purpose to examine lower limb melanoma (LLM) and its long-term survival rate, we used data from the Surveillance, ...
Dynamic estimates of survival in oncocytic cell carcinoma of the thyroid
Dynamic estimates of survival in oncocytic cell carcinoma of the thyroid
Little is known about death hazard and conditional survival of oncocytic cell carcinoma of the thyroid (OCC). Patients dia...
Mitophagy genes in ovarian cancer: a comprehensive analysis for improved immunotherapy
Mitophagy genes in ovarian cancer: a comprehensive analysis for improved immunotherapy
Mitophagy is a process of selectively degrading damaged mitochondria, which has been found to be related to immunity, tumo...
Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination
Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination
Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have semin...
Clinical application of 192Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck
Clinical application of 192Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck
The objective of this study was to investigate the safety and effectiveness of high-dose-rate brachytherapy as a treatment...
Functional and nonfunctional parathyroid carcinoma: two case reports and literature review
Functional and nonfunctional parathyroid carcinoma: two case reports and literature review
Parathyroid carcinoma (PC) is a rare malignant endocrine tumor. It can be divided into functional and non-functional types...
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