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Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
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Short-chain fatty acids ameliorate necrotizing enterocolitis-like intestinal injury through enhancing Notch1-mediated single immunoglobulin interleukin-1-related receptor, toll-interacting protein, and A20 induction
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Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Maternal hepatocytes heterogeneously and dynamically exhibit developmental phenotypes partially via yes-associated protein 1 during pregnancy
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Novel insights into physiological mechanisms underlying fecal continence
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Enterocyte-specific deletion of metal transporter Zip14 (Slc39a14) alters intestinal homeostasis through epigenetic mechanisms
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Tissue and cell specific properties of enterochromaffin cells affect the fate of tumorigenesis toward non-endocrine adenocarcinoma of the small intestine
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Metabolomics analysis of urine from patients with alcohol-associated liver disease reveals dysregulated caffeine metabolism
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Proteolipid protein 1 is involved in the regulation of intestinal motility and barrier function in the mouse
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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A Biomechanical Response of the Esophagus Participates in Swallowing
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Localized bioelectrical conduction block from radiofrequency gastric ablation persists after healing: safety and feasibility in a recovery model
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Spatial transcriptomics add a new dimension to our understanding of the gut
The profound complexity of the intestinal mucosa demands a spatial approach to the study of gut transcriptomics. Although ...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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Nutritional, pharmacological, and environmental programming of NAFLD in early life
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease
Hepatocyte- and macrophage-specific SREBP-1a knockout mice were generated for the first time. This study reveals that SREB...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Manganese efflux transporter SLC30A10 missense polymorphism T95I associated with liver injury retains manganese efflux activity
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Gastrointestinal organoids in the study of viral infections
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Inflammatory bowel disease therapeutic strategies by modulation of the microbiota: how and when to introduce pre-, pro-, syn-, or postbiotics?
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Cross talk between the gut microbiome and host immune response in ulcerative colitis: nonpharmacological strategies to improve homeostasis
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Esophageal wall compliance/stiffness during peristalsis in patients with functional dysphagia and high-amplitude esophageal contractions
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Loss of Apical Sodium Bile Acid Transporter Disrupts Bile Acid Circulation and Reduces Biliary Damage in Cholangitis
Background: Primary Sclerosing Cholangitis (PSC) is characterized by increased ductular reaction (DR), liver fibrosis, hep...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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Short Chain Fatty Acids Ameliorate Necrotizing enterocolitis-like Intestinal Injury through Enhancing Notch1-mediated SIGIRR, TOLLIP and A20 induction
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Dysbiosis and reduced small intestinal function are required to induce intestinal insufficiency in mice
Extensive bowel resection can lead to short bowel syndrome and intestinal failure. Resection-induced dysbiosis may be rela...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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β-PIX cooperates with GIT1 to regulate endothelial nitric oxide synthase in sinusoidal endothelial cells
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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Examining enteric nervous system function in rat and mouse: an interspecies comparison of colonic motility
Mice and rats are widely used in gastrointestinal research but have fundamental differences that make them important as di...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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Toll-like receptor 4 signaling pathway mediates both liver and kidney injuries in mice with hepatorenal syndrome
Our study established BDL, UUO, and BDL + UUO models, providing a novel idea for analyzing liver and kidney diseases. It i...
American Journal Of Physiology-gastrointestinal And Liver Physiology
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Coffee modulates insulin-hepatocyte nuclear factor-4α-Cyp7b1 pathway and reduces oxysterol-driven liver toxicity in a nonalcoholic fatty liver disease mouse model
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American Journal Of Physiology-gastrointestinal And Liver Physiology
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