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Quantitative analysis of systemic perfusion and cerebral blood flow in the modeling of aging and orthostatic hypotension
Quantitative analysis of systemic perfusion and cerebral blood flow in the modeling of aging and orthostatic hypotension
Introduction: Orthostatic hypotension (OH) is common among the older population. The mechanism hypothesized by OH as a ris...
Using spectral continuity to extract breathing rate from heart rate and its applications in sleep physiology
Using spectral continuity to extract breathing rate from heart rate and its applications in sleep physiology
Introduction: ECG Derived Respiration (EDR) are a set of methods used for extracting the breathing rate from the Electroca...
BFNet: a full-encoder skip connect way for medical image segmentation
BFNet: a full-encoder skip connect way for medical image segmentation
In recent years, semantic segmentation in deep learning has been widely applied in medical image segmentation, leading to ...
Asynchronous movement of sarcomeres in myocardium under living conditions: role of titin
Asynchronous movement of sarcomeres in myocardium under living conditions: role of titin
Myocardial performance is highly dependent on sarcomere length (SL), namely, SL-dependent activation, a basis of the Frank...
Ling-gui-zhu-gan granules reduces obesity and ameliorates metabolic disorders by inducing white adipose tissue browning in obese mice
Ling-gui-zhu-gan granules reduces obesity and ameliorates metabolic disorders by inducing white adipose tissue browning in obese mice
BackgroundLing-gui-zhu-gan (LGZG) formula has been demonstrated to effectively ameliorate the clinical symptoms of patient...
Defining adaptation within applied physiology – is there room for improvement?
Defining adaptation within applied physiology – is there room for improvement?
Importance of studying the process of adaptationThere is significant interdisciplinary interest in the biological mechanis...
Vicious cycle of oxidative stress and neuroinflammation in pathophysiology of chronic vascular encephalopathy
Vicious cycle of oxidative stress and neuroinflammation in pathophysiology of chronic vascular encephalopathy
Chronic vascular encephalopathy (CVE) is a frequent cause of vascular mild cognitive impairment and dementia, which signif...
Effect of circadian clock disruption on type 2 diabetes
Effect of circadian clock disruption on type 2 diabetes
IntroductionType 2 diabetes (T2D) is the predominant form of diabetes mellitus and is among the leading causes of death wi...
Update: factors influencing heart rate variability–a narrative review
Update: factors influencing heart rate variability–a narrative review
ObjectiveHeart rate variability (HRV) is an important non-invasive marker for the assessment of an organism’s autonomic ph...
Inertial measurement unit-based real-time feedback gait immediately changes gait parameters in older inpatients: a pilot study
Inertial measurement unit-based real-time feedback gait immediately changes gait parameters in older inpatients: a pilot study
The effect of gait feedback training for older people remains unclear, and such training methods have not been adapted in ...
Improved exercise ventilatory efficiency with nasal compared to oral breathing in cardiac patients
Improved exercise ventilatory efficiency with nasal compared to oral breathing in cardiac patients
Objectives: To assess whether nasal breathing improves exercise ventilatory efficiency in patients with heart failure (HF)...
Repeated seizure-induced brainstem neuroinflammation contributes to post-ictal ventilatory control dysfunction
Repeated seizure-induced brainstem neuroinflammation contributes to post-ictal ventilatory control dysfunction
Patients with epilepsy face heightened risk of post-ictal cardiorespiratory suppression and sudden unexpected death in epi...
Physiological analyses of swallowing changes due to chronic obstructive pulmonary disease in anesthetized male rats
Physiological analyses of swallowing changes due to chronic obstructive pulmonary disease in anesthetized male rats
Chronic obstructive pulmonary disease (COPD) was previously known as chronic bronchitis and emphysema. It has various main...
Automatic cardiothoracic ratio calculation based on lung fields abstracted from chest X-ray images without heart segmentation
Automatic cardiothoracic ratio calculation based on lung fields abstracted from chest X-ray images without heart segmentation
IntroductionThe cardiothoracic ratio (CTR) based on postero-anterior chest X-rays (P-A CXR) images is one of the most comm...
A deep learning radiomics model based on CT images for predicting the biological activity of hepatic cystic echinococcosis
A deep learning radiomics model based on CT images for predicting the biological activity of hepatic cystic echinococcosis
Introduction: Hepatic cystic echinococcosis (HCE) is a widely seen parasitic infection. Biological activity is crucial for...
Characterising cerebrovascular reactivity and the pupillary light response–a comparative study
Characterising cerebrovascular reactivity and the pupillary light response–a comparative study
IntroductionSmooth muscle is integral to multiple autonomic systems, including cerebrovascular dynamics through vascular s...
Automated identification of atrial fibrillation from single-lead ECGs using multi-branching ResNet
Automated identification of atrial fibrillation from single-lead ECGs using multi-branching ResNet
Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is clinically identified with irregula...
Editorial: Training and performance in swimming
Editorial: Training and performance in swimming
Swimming is part of the Olympic programme since 1896. Water Polo became the first team sport in the Games in 1900, and Div...
G protein βγ regulation of KCNQ-encoded voltage-dependent K channels
G protein βγ regulation of KCNQ-encoded voltage-dependent K channels
The KCNQ family is comprised of five genes and the expression products form voltage-gated potassium channels (Kv7.1–7.5) t...
Strain-controlled electrophysiological wave propagation alters in silico scar-based substrate for ventricular tachycardia
Strain-controlled electrophysiological wave propagation alters in silico scar-based substrate for ventricular tachycardia
Introduction: Assessing a patient’s risk of scar-based ventricular tachycardia (VT) after myocardial infarction is a chall...
Magnesium in hypertension: mechanisms and clinical implications
Magnesium in hypertension: mechanisms and clinical implications
Hypertension is associated with increased risk of cardiovascular disease and death. Evidence suggests that Mg2+ depletion ...
Titin: roles in cardiac function and diseases
Titin: roles in cardiac function and diseases
The giant protein titin is an essential component of muscle sarcomeres. A single titin molecule spans half a sarcomere and...
Anti-aging effect of glycerophosphocholine in Steinernema kraussei 0657L
Anti-aging effect of glycerophosphocholine in Steinernema kraussei 0657L
Glycerophosphocholine (GPC) is a water-soluble small molecule found naturally in humans and foods such as milk and soybean...
Erythroid anion transport, nitric oxide, and blood pressure
Erythroid anion transport, nitric oxide, and blood pressure
Glycophorin A and glycophorin B are structural membrane glycoproteins bound in the band 3 multiprotein complexes on human ...