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Quality of melatonin use in children and adolescents: findings from a UK clinical audit
WHAT IS ALREADY KNOWN ON THIS TOPICMelatonin is commonly prescribed in UK services for children and adolescents, principal...
Beneficial and harmful effects of tricyclic antidepressants for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis
WHAT IS ALREADY KNOWN ON THIS TOPICTricyclic antidepressants are used to treat major depressive disorder worldwide.The Nat...
Waiting-list interventions for children and young people using child and adolescent mental health services: a systematic review
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSWaiting list interventions have the potential to support children, ...
Framework for understanding movement and physical activity in patients diagnosed with psychosis
WHAT IS ALREADY KNOWN ON THIS TOPICA recognised priority in mental healthcare is to increase physical activity and decreas...
Single session of interpretation bias modification helped to improve fear of COVID-19 and COVID-19-related post-traumatic stress symptoms
BackgroundPost-traumatic stress symptoms (PTSS) include re-experiencing the traumatic experience, avoidance of stimuli ass...
Estimating the joint association of adverse childhood experiences and asthma with subsequent depressive symptoms: a marginal structural modelling approach
WHAT IS ALREADY KNOWN ON THIS TOPICAdverse childhood experiences (ACEs) and asthma are independent risk factors for elevat...
Influence of study characteristics, methodological rigour and publication bias on efficacy of pharmacotherapy in obsessive-compulsive disorder: a systematic review and meta-analysis of randomised, placebo-controlled trials
BackgroundObsessive-compulsive disorder (OCD) is characterised by persistent thoughts, images and/or sensory perceptions t...
Are web-based stress management interventions effective as an indirect treatment for depression? An individual participant data meta-analysis of six randomised trials
WHAT IS ALREADY KNOWN ON THIS TOPICWeb-based interventions have been shown to be effective in treating depression, but upt...
All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996-2019: a register study
WHAT IS ALREADY KNOWN ON THIS TOPICNo previous study has examined all-cause and suicide mortalities of gender-referred ado...
Predictors of increased affective symptoms and suicidal ideation during the COVID-19 pandemic: results from a large-scale study of 14 271 Thai adults
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSDuring the COVID-19 pandemic, an increase in affective symptoms pri...
Internet-based behavioural activation therapy versus online psychoeducation for self-reported suicidal ideation in individuals with depression in Indonesia: a secondary analysis of an RCT
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionSoutheast Asia has ...
Understanding effect size: an international online survey among psychiatrists, psychologists, physicians from other medical specialities, dentists and other health professionals
WHAT IS ALREADY KNOWN ON THIS TOPICMost effect size indices are poorly understood by clinicians.The magnitude of effect si...
Prescriptions of antidepressants and anxiolytics in France 2012-2022 and changes with the COVID-19 pandemic: interrupted time series analysis
Main findingsIn this ITS analysis of French outpatient pharmacy sales data, we found an increase in overall antidepressant...
Work Engagement and Well-being Study (SWELL): a randomised controlled feasibility trial evaluating the effects of mindfulness versus light physical exercise at work
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYWe found that an online MBP is ...
Suicide risk assessment tools and prediction models: new evidence, methodological innovations, outdated criticisms
The growing interest in precision psychiatry in recent years has led to a plethora of risk prediction models, both for the...
Bidirectional associations between mental disorders, antidepressants and cardiovascular disease
IntroductionCardiovascular diseases (CVDs) and mental disorders stand as two major classes of leading causes of death and ...
Psychological burden associated with incident persistent symptoms and their evolution during the COVID-19 pandemic: a prospective population-based study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThe psychological burden associated with persistent symptoms that o...
Tracing Tomorrow: young peoples preferences and values related to use of personal sensing to predict mental health, using a digital game methodology
WHAT IS ALREADY KNOWN ON THIS TOPICThere is substantive literature on the communication of health risk information followi...
Data reduction when aggregating information about harms associated with medical interventions
In interpreting and aggregating data in published reports, readers and authors must be aware that some data loss and trans...
Psychiatric admissions in young people after expiration of criminal justice supervision in Australia: a retrospective data linkage study
BackgroundYoung people involved in the criminal justice system have a higher prevalence of psychiatric disorders compared ...
Understanding the protective effect of social support on depression symptomatology from a longitudinal network perspective
WHAT IS ALREADY KNOWN ON THIS TOPICMultiple theories have been proposed to explain why social support from others is assoc...
Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving
WHAT IS ALREADY KNOWN ON THIS TOPICSelf-stigma has a negative impact on the well-being of individuals with alcohol use dis...
Genetically predicted causal associations between periodontitis and psychiatric disorders
WHAT IS ALREADY KNOWN ON THIS TOPICPsychiatric disorders have serious harm to individuals’ lives with high disease burden....
Comparative analysis of algorithm-guided treatment and predefined duration treatment programmes for depression: exploring cost-effectiveness using routine care data
WHAT IS ALREADY KNOWN ON THIS TOPICPrior research has established the effectiveness of algorithm-guided programmes for dep...
Tool to assess risk of bias in studies estimating the prevalence of mental health disorders (RoB-PrevMH)
We developed RoB-PrevMH, a concise RoB tool for prevalence studies in mental health that was designed with the intention t...
Relationship between severe mental illness and physical multimorbidity: a meta-analysis and call for action
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionMental health is a ...
School-based Evaluation Advancing Response for Child Health (SEARCH): a mixed longitudinal cohort study from multifaceted perspectives in Jiangsu, China
WHAT IS ALREADY KNOWN ON THIS TOPICThe existing literature highlights the limited capacity of school-based mental health s...
Early parenting interventions to prevent internalising problems in children and adolescents: a global systematic review and network meta-analysis
BackgroundIn 2022, the WHO identified internalising problems (eg, anxiety and depression) as a priority outcome when evalu...
Treatments for partial remission of major depressive disorder: a systematic review and meta-analysis
Selection and characteristics of included studiesAfter removal of duplicates, 5450 records were identified and screened. O...
Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data
WHAT IS ALREADY KNOWN ON THIS TOPICIn recent years, there has been an increase in mental health issues and antidepressant ...
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