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The Role of Ovarian Granulosa Cells Related-ncRNAs in Ovarian Dysfunctions: Mechanism Research and Clinical Exploration
The Role of Ovarian Granulosa Cells Related-ncRNAs in Ovarian Dysfunctions: Mechanism Research and Clinical Exploration
Ovarian dysfunctions, encompassing conditions such as polycystic ovary syndrome (PCOS), premature ovarian failure (POF), p...
Identification of an  Mutation Associated With Necrozoospermia and Failure of Testi-ICSI
Identification of an Mutation Associated With Necrozoospermia and Failure of Testi-ICSI
Investigating potential etiologies is important before selecting a therapeutic approach for male infertility. However, the...
Single-Cell Transcriptome and RNA Sequencing Reveal Immune-Related Markers of Preeclampsia
Single-Cell Transcriptome and RNA Sequencing Reveal Immune-Related Markers of Preeclampsia
Preeclampsia is a leading cause of maternal and fetal mortality, posing a threat to the mother and fetus’s lives, bu...
The Regulation of ZAR1 on Apoptosis and Mitophagy in Ovarian Granular Cells and Primary Ovarian Insufficiency (POI) Mice
The Regulation of ZAR1 on Apoptosis and Mitophagy in Ovarian Granular Cells and Primary Ovarian Insufficiency (POI) Mice
Primary ovarian insufficiency (POI) has become a serious problem causing infertility and endocrine disorders in women of c...
Impact of Antidepressants on Male Fertility and Seminal Parameters: A Systematic Review
Impact of Antidepressants on Male Fertility and Seminal Parameters: A Systematic Review
Depressive disorders affect a significant number of individuals worldwide, including men of reproductive age. The impact o...
Maternal Thrombophilia Disrupts Fetal Redox Homeostasis
Maternal Thrombophilia Disrupts Fetal Redox Homeostasis
Considering that the fetal redox homeostasis is a key factor for normal prenatal development, this study researched the ef...
Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo
Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo
Recent years have seen a global increase in infertility, affecting up to 17.5% of the population. For successful human rep...
Melatonin Rescues Hyperacetylation of Liver and Impaired Enzymatic Activities of Mitochondrial in IVF Offspring
Melatonin Rescues Hyperacetylation of Liver and Impaired Enzymatic Activities of Mitochondrial in IVF Offspring
Increased risks of obesity and abnormal glucose metabolism were observed in IVF offspring. However, the underlying molecul...
Barriers to Diagnosis and Treatment for Premenstrual Dysphoric Disorder (PMDD): A Scoping Review
Barriers to Diagnosis and Treatment for Premenstrual Dysphoric Disorder (PMDD): A Scoping Review
Premenstrual dysphoric disorder (PMDD) is a significant public health challenge. While research has increased over the pas...
A Novel  Mutation Causes Hypospadias in a Chinese Fetus at 29 Weeks Gestation
A Novel Mutation Causes Hypospadias in a Chinese Fetus at 29 Weeks Gestation
KAT6B mutations are responsible for Say-Barber-Biesecker-Young-Simpson syndrome or Genitopatellar syndrome, with most muta...
From Dominant Assumptions to Recessive Trait: Rethinking  in Ovarian Dysfunction
From Dominant Assumptions to Recessive Trait: Rethinking in Ovarian Dysfunction
Approximately 1% of women experience premature ovarian insufficiency (POI) before the age of 40. Genetic factors play a si...
Rosiglitazone-Mediated Activation of PPARγ Induces PlGF Expression in Trophoblast Cells
Rosiglitazone-Mediated Activation of PPARγ Induces PlGF Expression in Trophoblast Cells
Preeclampsia (PE) is a hypertensive pregnancy disorder marked by impaired trophoblast invasion and placental vascular dysf...
High Prevalence of Anti-Prothrombin IgM and IgG Autoantibodies in Women With Unexplained Recurrent Pregnancy Loss
High Prevalence of Anti-Prothrombin IgM and IgG Autoantibodies in Women With Unexplained Recurrent Pregnancy Loss
To investigate the association between anti-prothrombin IgM and IgG antibodies and recurrent pregnancy loss (RPL) in a coh...
Correlation study of NF-κB, IER3, and Recurrence of Ovarian Endometrioid Cysts
Correlation study of NF-κB, IER3, and Recurrence of Ovarian Endometrioid Cysts
The study aimed to investigate the expression of nuclear actor-k-gene binding(NF-κB) and immediate early response 3(I...
Cancer-associated Fibroblasts-derived Exosomes with HOXD11 Overexpression Promote Ovarian Cancer Cell Angiogenesis Via FN1
Cancer-associated Fibroblasts-derived Exosomes with HOXD11 Overexpression Promote Ovarian Cancer Cell Angiogenesis Via FN1
Cancer-associated fibroblasts (CAFs) represent a critical stromal component of metastatic niche and promote metastasis in ...
Mesenchymal Stromal Cell Exosome-Induced Vascular Regeneration in a PCOS Mouse Model
Mesenchymal Stromal Cell Exosome-Induced Vascular Regeneration in a PCOS Mouse Model
The efficacy of Bone Marrow Mesenchymal Stem Cell-derived Exosomes (BMSCs-Exo) in addressing the complexities of Polycysti...
Effects of Thyroid Hormones on Cellular Development in Human Ovarian Granulosa Tumor Cells (KGN)
Effects of Thyroid Hormones on Cellular Development in Human Ovarian Granulosa Tumor Cells (KGN)
Ovarian cancer is a common malignant tumor in the female reproductive system, and Granulosa cell tumor (GCT) of the ovary ...
Characterizing the Impact of Dysregulated Micrornas on CRISP3 Isoforms in Male Infertility
Characterizing the Impact of Dysregulated Micrornas on CRISP3 Isoforms in Male Infertility
microRNAs (miRNAs) have a serious and dynamic function in spermatogenesis. These molecules have been recognized as crucial...
Impact of COVID-19 Vaccination on Female Fertility
Impact of COVID-19 Vaccination on Female Fertility
Despite evidence in previous literature regarding vaccine safety, more data were needed as concerns about COVID-19 vaccine...
The Value of Androgen Measures for Diagnosing Polycystic Ovary Syndrome (PCOS) in an Unselected Population
The Value of Androgen Measures for Diagnosing Polycystic Ovary Syndrome (PCOS) in an Unselected Population
Polycystic Ovary Syndrome (PCOS) is diagnosed by a combination of three features: hyperandrogenism (biochemical and/or cli...
Identification and Manipulation of Spermatogonial Stem Cells with the Aim of Inducing Spermatogenesis in Vitro
Identification and Manipulation of Spermatogonial Stem Cells with the Aim of Inducing Spermatogenesis in Vitro
Assisted reproduction techniques for infertile men with non-obstructive azoospermia require a sufficient number of functio...
Non Invasive Preimplantation Testing for Aneuploidies in Assisted Reproduction: A SWOT Analysis
Non Invasive Preimplantation Testing for Aneuploidies in Assisted Reproduction: A SWOT Analysis
The implementation of non-invasive PGT-A offers a new strategy to genetically assess the preimplantation embryo and to enh...
A Compound Heterozygous Pathogenic Variant in ZP2 Gene Causes Female Infertility
A Compound Heterozygous Pathogenic Variant in ZP2 Gene Causes Female Infertility
The oocyte maturation defect 6 is an autosomal recessive hereditary disease caused by a homozygous variant in ZP2 gene. It...
Piceatannol Protects Sperm from Cryopreservation Damage by Modulating the Keap1-Nrf2/ARE Signaling Pathway
Piceatannol Protects Sperm from Cryopreservation Damage by Modulating the Keap1-Nrf2/ARE Signaling Pathway
The purpose of this study was to explore the mechanism of action of Piceatannol (PIC) in attenuating oxidative damage to s...