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Injectable composite hydrogels embedded with gallium-based liquid metal particles for solid breast cancer treatment via chemo-photothermal combination
Injectable composite hydrogels embedded with gallium-based liquid metal particles for solid breast cancer treatment via chemo-photothermal combination
Nowadays, cancer incidence and associated mortality are still major concerns [1]. However, current treatments are limited ...
Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration
Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration
Low back pain is a leading cause of disability worldwide, often attributed to intervertebral disc (IVD) degeneration with ...
Multimodal phototherapy agents target lipid droplets for near-infrared imaging-guided type I photodynamic/photothermal therapy
Multimodal phototherapy agents target lipid droplets for near-infrared imaging-guided type I photodynamic/photothermal therapy
Phototherapy includes photodynamic therapy (PDT) and photothermal therapy (PTT). Compared with surgical resection, chemoth...
Protein adsorption on blood-contacting surfaces: A thermodynamic perspective to guide the design of antithrombogenic polymer coatings
Protein adsorption on blood-contacting surfaces: A thermodynamic perspective to guide the design of antithrombogenic polymer coatings
Available online 12 April 2024Author links open overlay panel, , , , AbstractBlood-contacting medical devices often succum...
Gallium and silver-doped titanium surfaces provide enhanced osteogenesis, reduce bone resorption and prevent bacterial infection in co-culture
Gallium and silver-doped titanium surfaces provide enhanced osteogenesis, reduce bone resorption and prevent bacterial infection in co-culture
Available online 14 April 2024Author links open overlay panel, , , , , , , AbstractBacterial infection remains a significa...
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect
The treatment of osteoporotic bone defect remains a big clinical challenge because osteoporosis (OP) is associated with ox...
In vivo assessment of dual-function submicron textured nitric oxide releasing catheters in a 7-day rabbit model
In vivo assessment of dual-function submicron textured nitric oxide releasing catheters in a 7-day rabbit model
Intravascular catheter insertion is common in hospitals and outpatient settings for various purposes, such as administerin...
A Fully Biodegradable Spherical Nucleic Acid Nanoplatform for Self-codelivery of Doxorubicin and miR122 for Innate and Adaptive Immunity Activation
A Fully Biodegradable Spherical Nucleic Acid Nanoplatform for Self-codelivery of Doxorubicin and miR122 for Innate and Adaptive Immunity Activation
Polycation-mediated traditional chemo-gene therapy generally suffers from low transfection efficiency and carriers-associa...
Decellularized Extracellular Matrix enriched with GDNF Enhances Neurogenesis and Remyelination for Improved Motor Recovery after Spinal Cord Injury
Decellularized Extracellular Matrix enriched with GDNF Enhances Neurogenesis and Remyelination for Improved Motor Recovery after Spinal Cord Injury
Spinal cord injury (SCI), an intractable neurological disorder, results in neurodegeneration and motor dysfunction, leadin...
Inflammatory tissue response in human soft tissue is caused by a higher particle load near carbon fiber-reinforced PEEK compared to titanium plates
Inflammatory tissue response in human soft tissue is caused by a higher particle load near carbon fiber-reinforced PEEK compared to titanium plates
Titanium as the leading implant material in locked plating is challenged by polymers such as carbon fiber-reinforced polye...
Unveiling clinical applications of bacterial extracellular vesicles as natural nanomaterials in disease diagnosis and therapeutics
Unveiling clinical applications of bacterial extracellular vesicles as natural nanomaterials in disease diagnosis and therapeutics
Bacterial extracellular vesicles (BEVs) are naturally occurring bioactive membrane-bound nanoparticles released by both gr...
Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells within a 3D, Active Fluid-Structure Interaction Culture Environment
Comparative Analysis of Traction Forces in Normal and Glaucomatous Trabecular Meshwork Cells within a 3D, Active Fluid-Structure Interaction Culture Environment
Primary open-angle glaucoma (POAG), a leading cause of irreversible vision loss, is primarily associated with increased in...
Lymph node targeting strategy using a hydrogel sustained-release system to load effector memory T cells improves the anti-tumor efficacy of anti-PD-1
Lymph node targeting strategy using a hydrogel sustained-release system to load effector memory T cells improves the anti-tumor efficacy of anti-PD-1
Immune checkpoint blockade (ICB) therapies targeting programmed cell death protein 1/programmed cell death ligand 1 (PD-1/...
Decellularized Kidney Extracellular Matrix-Based Hydrogels for Renal Tissue Engineering
Decellularized Kidney Extracellular Matrix-Based Hydrogels for Renal Tissue Engineering
Available online 18 April 2024Author links open overlay panel, , , , , , AbstractKidney regeneration is hindered by the li...
A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery
A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery
Transdermal drug delivery system (TDDS) has been one of the most popular dosage forms expected to replace oral administrat...
Unraveling the influence of channel size and shape in 3D printed ceramic scaffolds on osteogenesis
Unraveling the influence of channel size and shape in 3D printed ceramic scaffolds on osteogenesis
Available online 18 April 2024Author links open overlay panel, , , , , , , , AbstractBone has the capacity to regenerate i...
Architecture of β-Lactoglobulin Coating Modulates Bioinspired Alginate Dialdehyde-Gelatine/Polydopamine Scaffolds for Subchondral Bone Regeneration
Architecture of β-Lactoglobulin Coating Modulates Bioinspired Alginate Dialdehyde-Gelatine/Polydopamine Scaffolds for Subchondral Bone Regeneration
In this study, we developed polydopamine (PDA)-functionalized alginate dialdehyde-gelatine (ADA-GEL) scaffolds for subchon...
Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice
Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice
Obesity, characterized by a body mass index (BMI) exceeding 30 kg/m2, is a significant public health concern affecting a c...
In vivo Micro-computed Tomography Evaluation of Radiopaque, Polymeric Device Degradation in Normal and Inflammatory Environments
In vivo Micro-computed Tomography Evaluation of Radiopaque, Polymeric Device Degradation in Normal and Inflammatory Environments
Biomedical devices fulfill many important roles in regenerative medicine: stabilizing injured tissue, supporting repair af...
A One-Two Punch Strategy for Diabetic Wound Management Based on an Antibiotic-Hybrid Biomineralized Iron Sulfide Nanoparticle
A One-Two Punch Strategy for Diabetic Wound Management Based on an Antibiotic-Hybrid Biomineralized Iron Sulfide Nanoparticle
Diabetes constitutes a significant and escalating global concern. According to estimations by the International Diabetes F...
Cholla Cactus Wood (Cylindropuntia imbricata): Hierarchical Structure and Micromechanical Properties
Cholla Cactus Wood (Cylindropuntia imbricata): Hierarchical Structure and Micromechanical Properties
Available online 9 December 2023Author links open overlay panel, , , , , , AbstractThe Cholla cactus is a species of cacti...
Incorporating pH/NIR responsive nanocontainers into a smart self-healing coating for a magnesium alloy with controlled drug release, bacteria killing and osteogenesis properties
Incorporating pH/NIR responsive nanocontainers into a smart self-healing coating for a magnesium alloy with controlled drug release, bacteria killing and osteogenesis properties
Available online 9 December 2023Author links open overlay panel, , , , , AbstractMagnesium (Mg)-based orthopedic implant m...
Spatial targeting of fibrosis-promoting macrophages with nanoscale metal-organic frameworks for idiopathic pulmonary fibrosis therapy
Spatial targeting of fibrosis-promoting macrophages with nanoscale metal-organic frameworks for idiopathic pulmonary fibrosis therapy
Targeted delivery of therapeutic drugs to fibrosis-promoting macrophages (FPMs) holds promise as a challenging yet effecti...
The morphology of the interfacial tissue between bighorn sheep horn and bony horncore increases contact surface to enhance strength and facilitate load transfer from the horn to the horncore
The morphology of the interfacial tissue between bighorn sheep horn and bony horncore increases contact surface to enhance strength and facilitate load transfer from the horn to the horncore
Available online 9 December 2023Author links open overlay panel, , , , AbstractThe horns of bighorn sheep rams are permane...
Functionalisation of brush polyethylene glycol polymers with specific lipids extends their elimination half-life through association with natural lipid trafficking pathways
Functionalisation of brush polyethylene glycol polymers with specific lipids extends their elimination half-life through association with natural lipid trafficking pathways
Polymeric prodrugs have been applied to control the delivery of various types of therapeutics. Similarly, conjugation of p...
In vitro dose-dependent effects of matrix metalloproteinases on ECM hydrogel biodegradation.
In vitro dose-dependent effects of matrix metalloproteinases on ECM hydrogel biodegradation.
Available online 10 December 2023Author links open overlay panel, , , AbstractMatrix metalloproteinases (MMPs) cause prote...
Corrigendum to “ECM-based bioactive microencapsulation significantly improves islet function and graft performance” [Acta Biomaterialia. Volume 171, November 2023, Pages 249-260]
Corrigendum to “ECM-based bioactive microencapsulation significantly improves islet function and graft performance” [Acta Biomaterialia. Volume 171, November 2023, Pages 249-260]
Available online 6 December 2023Author links open overlay panelStasia Krishtul a, Michal Skitel Moshe a b, Inna Kovrigina ...
Comprehensive modeling of annulus fibrosus: from biphasic refined characterization to damage accumulation under viscous loading
Comprehensive modeling of annulus fibrosus: from biphasic refined characterization to damage accumulation under viscous loading
Available online 7 December 2023Author links open overlay panel, , AbstractThe annulus fibrosus (AF), a permeable, hydrate...
Scaffolded spheroids as building blocks for bottom-up cartilage tissue engineering show enhanced bioassembly dynamics
Scaffolded spheroids as building blocks for bottom-up cartilage tissue engineering show enhanced bioassembly dynamics
Due to the capability of cell spheroids (SPH) to assemble into large high cell density constructs, their use as building b...
Intelligent wound dressing for simultaneous in situ detection and elimination of pathogenic bacteria
Intelligent wound dressing for simultaneous in situ detection and elimination of pathogenic bacteria
Wound infections hinder the healing process and potentially result in life-threatening complications, which urgently requi...
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