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EAACI position paper on the clinical use of the bronchial allergen challenge: unmet needs and research priorities
EAACI position paper on the clinical use of the bronchial allergen challenge: unmet needs and research priorities
Abstract Allergic asthma (AA) is a common asthma phenotype and its diagnosis requires both the demonstration of IgE-sensit...
Epigenetic regulation of epithelial dectin‐1 through an IL‐33‐STAT3 axis in allergic disease
Epigenetic regulation of epithelial dectin‐1 through an IL‐33‐STAT3 axis in allergic disease
Abstract Allergic diseases arise in susceptible individuals in part because of decrements in protective pathways. The mech...
Adherence to subcutaneous immunotherapy with aeroallergens in real‐life practice during the COVID‐19 pandemic
Adherence to subcutaneous immunotherapy with aeroallergens in real‐life practice during the COVID‐19 pandemic
Abstract Background The success of subcutaneous immunotherapy (SCIT) mostly depends on regular injections. Our aim was to ...
The ingenious mast cell: Contemporary insights into mast cell behavior and function
The ingenious mast cell: Contemporary insights into mast cell behavior and function
Abstract Mast cells are (in)famous for their role in allergic diseases, but the physiological and pathophysiological roles...
In this issue: Graphical abstract
In this issue: Graphical abstract
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Neonatal airway immune profiles and asthma and allergy endpoints in childhood
Neonatal airway immune profiles and asthma and allergy endpoints in childhood
Abstract Background The immune system plays a key role in the pathogenesis of asthma and allergy, but the role of the airw...
Safety of the standardized quality tree sublingual immunotherapy tablet: Pooled safety analysis of clinical trials
Safety of the standardized quality tree sublingual immunotherapy tablet: Pooled safety analysis of clinical trials
Abstract Background The standardized quality (SQ) tree sublingual immunotherapy (SLIT)-tablet has recently been approved f...
Development and validation of combined symptom‐medication scores for allergic rhinitis
Development and validation of combined symptom‐medication scores for allergic rhinitis
Summary Background Validated combined symptom-medication scores (CSMSs) are needed to investigate the effects of allergic ...
Molecular sensitization patterns in animal allergy: Relationship with clinical relevance and pet ownership
Molecular sensitization patterns in animal allergy: Relationship with clinical relevance and pet ownership
Abstract Background In vitro diagnosis using single molecules is increasingly complementing conventional extract-based dia...
Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize NSAID‐exacerbated respiratory disease
Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize NSAID‐exacerbated respiratory disease
This article has been accepted for publication and undergone full peer review but has not been through the co...
Baseline type 2 biomarker levels and response to tezepelumab in severe asthma
Baseline type 2 biomarker levels and response to tezepelumab in severe asthma
Abstract Background Tezepelumab is a human monoclonal antibody that blocks activity of thymic stromal lymphopoietin (TSLP)...
Isolation of nanobodies with potential to reduce patients' IgE binding to Bet v 1
Isolation of nanobodies with potential to reduce patients' IgE binding to Bet v 1
Abstract Background Recent studies showed that a single injection of human monoclonal allergen-specific IgG antibodies sig...
IgE‐sensitization predicts threshold but not anaphylaxis during oral food challenges to cow's milk
IgE‐sensitization predicts threshold but not anaphylaxis during oral food challenges to cow's milk
There are increasing data relating to predicting the outcomes of oral food challenges (FC) to peanut, specifically severit...
Diversity and complexity of mouse allergens in urine, house dust, and allergen extracts assessed with an immuno‐allergomic approach
Diversity and complexity of mouse allergens in urine, house dust, and allergen extracts assessed with an immuno‐allergomic approach
Abstract Background Mouse allergy is an important cause of indoor asthma and allergic rhinoconjunctivitis. The major mouse...
Understanding uncontrolled severe allergic asthma by integration of omic and clinical data
Understanding uncontrolled severe allergic asthma by integration of omic and clinical data
Abstract Background Asthma is a complex, multifactorial disease often linked with sensitization to house dust mites (HDM)....
IgE sensitisation predicts threshold but not anaphylaxis during oral food challenges to cow’s milk
IgE sensitisation predicts threshold but not anaphylaxis during oral food challenges to cow’s milk
This article has been accepted for publication and undergone full peer review but has not been through the co...
Immunological resilience and biodiversity for prevention of allergic diseases and asthma
Immunological resilience and biodiversity for prevention of allergic diseases and asthma
Abstract Increase of allergic conditions has occurred at the same pace with the Great Acceleration, which stands for the r...
Innovative robust basophil activation test using a novel gating strategy reliably diagnosing allergy with full automation
Innovative robust basophil activation test using a novel gating strategy reliably diagnosing allergy with full automation
Abstract Background Allergy is one of the most common chronic diseases in Europe. Therefore, an increased need for specifi...
T regulatory cells from atopic asthmatic individuals show a Th2‐like phenotype
T regulatory cells from atopic asthmatic individuals show a Th2‐like phenotype
Corresponding Author Swiss Institute of Allergy and Asthma Research (SIAF), Uni...
In this Issue: Graphical Abstracts
In this Issue: Graphical Abstracts
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Risk factors for systemic reactions in typical cold urticaria: results from the COLD‐CE study
Risk factors for systemic reactions in typical cold urticaria: results from the COLD‐CE study
ABSTRACT Background Cold urticaria (ColdU), i.e. the occurrence of wheals or angioedema in response to cold exposure, is c...
Analysis of BNT162b2‐ and CVnCoV‐elicited sera and of convalescent sera toward SARS‐CoV‐2 viruses
Analysis of BNT162b2‐ and CVnCoV‐elicited sera and of convalescent sera toward SARS‐CoV‐2 viruses
Summary Background The mRNA vaccine BNT162b2 (Comirnaty, BioNTech/Pfizer) and the vaccine candidate CVnCoV (Curevac) each ...
Bovine γ‐globulin, lactoferrin, and lactoperoxidase are relevant bovine milk allergens in patients with α‐Gal syndrome
Bovine γ‐globulin, lactoferrin, and lactoperoxidase are relevant bovine milk allergens in patients with α‐Gal syndrome
Abstract Background Mammalian meat is the most common trigger of the allergic reactions in patients with α-Gal syndr...
Women in science and medicine
Women in science and medicine
1 INTRODUCTION Science and medicine know no barriers, no country, and no language. They are universal t...