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Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Food allergies are immune-mediated, complex disorders, which are the source of increasing health concern worldwide. The go...
Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study)
Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study)
We aimed to reach an Italian multidisciplinary consensus on some crucial aspects of treatment decision making in CRSwNP, f...
Reversible Elevation of Tryptase Over the Individual's Baseline: Why is It the Best Biomarker for Severe Systemic Mast Cell Activation and MCAS?
Reversible Elevation of Tryptase Over the Individual's Baseline: Why is It the Best Biomarker for Severe Systemic Mast Cell Activation and MCAS?
Mast cell (MC) activation syndromes (MCAS) are conditions defined by recurrent episodes of severe systemic anaphylaxis or ...
Precautionary Allergen Labeling: Avoidance for All?
Precautionary Allergen Labeling: Avoidance for All?
Precautionary allergen labeling (PAL) suggests the risk of unintended allergen presence (UAP) in food but is unregulated i...
The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults
The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults
This narrative review explores food allergy prevalence and natural history stratified by life stages, especially in contex...
Recent Insights into the Environmental Determinants of Childhood Asthma
Recent Insights into the Environmental Determinants of Childhood Asthma
Ubiquitous environmental exposures, including ambient air pollutants, are linked to the development and severity of childh...
What the SARS-CoV-2 Pandemic Has Taught Us About Immunosuppression, Vaccinations, and Immune Dysregulation: The Rheumatology Experience
What the SARS-CoV-2 Pandemic Has Taught Us About Immunosuppression, Vaccinations, and Immune Dysregulation: The Rheumatology Experience
This review reflects on the impact of the COVID-19 pandemic on the field of rheumatology, emphasizing resulting insights r...
Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations
Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations
Neurogenesis occurring in the olfactory epithelium is critical to continuously replace olfactory neurons to maintain olfac...
Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell–Mediated Reactions
Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell–Mediated Reactions
To provide an overview on the current understanding of genetic variability in human tryptases and summarize the literature...
Fungal Sensitization and Human Allergic Disease
Fungal Sensitization and Human Allergic Disease
Fungal sensitizations have been associated with hypersensitivity reactions with variable levels of evidence available to l...
Biomarkers of Autoimmune Chronic Spontaneous Urticaria
Biomarkers of Autoimmune Chronic Spontaneous Urticaria
Chronic spontaneous urticaria and chronic inducible urticaria (CSU/CindU) are caused by mast cell and basophil activation ...
The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction
The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction
With increasing industrialization, exposure to ambient and wildfire air pollution is projected to increase, necessitating ...
Effects of Endoscopic Sinus Surgery on Olfactory Function
Effects of Endoscopic Sinus Surgery on Olfactory Function
To review the effects of endoscopic sinus surgery and endonasal approaches to the skull base on olfaction. Advancements in...
Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP
Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP
Three biologics targeting type 2 inflammation have been approved for the treatment of severe and uncontrolled chronic rhin...
Endoscopic Extended Sinus Surgery for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps, the Choice of Mucoplasty: A Systematic Review
Endoscopic Extended Sinus Surgery for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps, the Choice of Mucoplasty: A Systematic Review
The advances in the knowledge of the molecular basis of the inflammatory response in chronic rhinosinusitis with nasal pol...
Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach
Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach
A modified Delphi process was undertaken to provide a US expert-led consensus to guide clinical action on short-acting bet...
Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis
Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis
To analyze and compare the effects of epistaxis treatments for Hereditary Hemorrhagic Telangiectasia (HHT) patients. Of to...
Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases
Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases
Neuromyelitis optica (NMO) is an auto-immune disease essentially depicted by optic neuritis and transverse myelitis. Per s...
An Emerging Role of Extracellular Traps in Chronic Rhinosinusitis
An Emerging Role of Extracellular Traps in Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a complicated, heterogeneous disease likely caused by inflammatory and infectious factors....
Overview and Current Advances in Dapsone Hypersensitivity Syndrome
Overview and Current Advances in Dapsone Hypersensitivity Syndrome
As a sulfone antibacterial agent, dapsone has been widely used to treat leprosy. Moreover, dapsone is also used in many im...
Allergen Stability in Food Allergy: A Clinician’s Perspective
Allergen Stability in Food Allergy: A Clinician’s Perspective
The globally rising food allergy prevalence is associated with the urgent need for new disease prevention methods, efficie...
Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
This review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in school...
Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
Despite molecular underlying advances, limited and divergent data on monoclonal antibodies (mAb) therapy in chron...
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
Immunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention ...
Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
Mechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient’s quality-of-life (QoL) an...
Air Pollution and Diet: Potential Interacting Exposures in Asthma
Air Pollution and Diet: Potential Interacting Exposures in Asthma
To provide a review of emerging literature describing the impact of diet on the respiratory response to air pollution in a...
Occupational Rhinitis: An Update
Occupational Rhinitis: An Update
Occupational rhinitis is an underdiagnosed disease with significant morbidity and implications in the workplace. Multiple ...
Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist
Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist
Provide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye diseas...
The Use and Teaching of Telemedicine in Allergy/Immunology Training Programs
The Use and Teaching of Telemedicine in Allergy/Immunology Training Programs
The use of telemedicine has greatly increased since the onset of the coronavirus disease 2019 (COVID-19) pandemic. This re...
Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic
Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic
Environmental home assessments have traditionally been performed in-person at the homes of Children’s Mercy Kansas C...
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