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Parosmia: Pathophysiology and Management
Parosmia: Pathophysiology and Management
Parosmia is a qualitative olfactory disorder in which there is a mismatch between the memory of an odor and the actual exp...
The Impact of the Indoor Environment on Childhood Asthma
The Impact of the Indoor Environment on Childhood Asthma
This manuscript reviews the impact of important indoor environmental exposures on pediatric asthma, with a focus on recent...
Hypersensitivity Reactions to Anticonvulsants
Hypersensitivity Reactions to Anticonvulsants
Antiepileptics are the mainstay of treatment for seizure management. Immediate and delayed hypersensitivity reactions asso...
Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis
Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating inflammatory condition that significantly impacts qual...
Burden of Respiratory Syncytial Virus Disease in Adults with Asthma and Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Burden of Respiratory Syncytial Virus Disease in Adults with Asthma and Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Accumulating data indicate that asthma and chronic obstructive pulmonary disease (COPD) increase the risk of severe respir...
Hyper IgE Syndrome: Bridging the Gap Between Immunodeficiency, Atopy, and Allergic Diseases
Hyper IgE Syndrome: Bridging the Gap Between Immunodeficiency, Atopy, and Allergic Diseases
It seeks to answer key questions about the molecular and cellular mechanisms underlying Hyper IgE Syndrome (HIES), the gen...
T Cell Exhaustion in Allergic Diseases and Allergen Immunotherapy: A Novel Biomarker?
T Cell Exhaustion in Allergic Diseases and Allergen Immunotherapy: A Novel Biomarker?
This review explores the emerging role of T cell exhaustion in allergic diseases and allergen immunotherapy (AIT). It aims...
Basophil Activation Test for the Improved Diagnosis of Peanut and Tree Nut Allergy
Basophil Activation Test for the Improved Diagnosis of Peanut and Tree Nut Allergy
As an ex-vivo test of allergic effector cell activation, basophil activation testing (BAT) to allergen enables quantificat...
Climate Change and the Future of Allergies and Asthma
Climate Change and the Future of Allergies and Asthma
Climate change affects global temperature, meteorological variables, plant aerobiology, air pollution exposure and a host ...
Managing Chronic Urticaria in Children: An Update
Managing Chronic Urticaria in Children: An Update
To provide an update and new insights into the management of pediatric patients with chronic urticaria. Chronic urticaria ...
Occupational Respiratory Allergy to Flour in the Modern Era
Occupational Respiratory Allergy to Flour in the Modern Era
A comprehensive literature review was conducted in order to identify and summarize recent research on IgE-mediated occupat...
Pediatric Systemic Autoinflammatory Disorders: An Overview
Pediatric Systemic Autoinflammatory Disorders: An Overview
Systemic autoinflammatory disorders (SAIDs) are a group of diseases that are characterized by recurrent or persistent unpr...
Metabolomics in Childhood Asthma – a Promising Tool to Meet Various Clinical Needs
Metabolomics in Childhood Asthma – a Promising Tool to Meet Various Clinical Needs
The aim of our review is to summarize the available literature where metabolomics was used in studies on childhood asthma,...
Respiratory Health Impacts from Natural Disasters and Other Extreme Weather Events: The Role of Environmental Stressors on Asthma and Allergies
Respiratory Health Impacts from Natural Disasters and Other Extreme Weather Events: The Role of Environmental Stressors on Asthma and Allergies
The frequency of natural disasters, other extreme weather events, and downstream emissions of emerging contaminants is inc...
AI-Driven Biomarker Discovery and Personalized Allergy Treatment: Utilizing Machine Learning and NGS
AI-Driven Biomarker Discovery and Personalized Allergy Treatment: Utilizing Machine Learning and NGS
This review explores the transformative potential of artificial intelligence (AI) and next-generation sequencing (NGS) in ...
Emergency Monitoring Following A Diagnosis of Anaphylaxis
Emergency Monitoring Following A Diagnosis of Anaphylaxis
In this review we explore expanding options for monitoring following anaphylaxis in the home or community setting. We revi...
Oral Janus Kinase Inhibitors in Pediatric Atopic Dermatitis
Oral Janus Kinase Inhibitors in Pediatric Atopic Dermatitis
To analyze the efficacy and safety of Janus kinase inhibitors (JAKi) in the treatment of pediatric AD. Adolescents with mo...
Legume Allergens Pea, Chickpea, Lentil, Lupine and Beyond
Legume Allergens Pea, Chickpea, Lentil, Lupine and Beyond
In the last decade, an increasing trend towards a supposedly healthier vegan diet could be observed. However, recently, mo...
Impact of Enolase in Allergic Disease
Impact of Enolase in Allergic Disease
There is growing evidence that enolase is involved in allergy. This manuscript reviews the impact of enolase in allergic d...
Childhood-Onset Systemic Lupus Erythematosus (cSLE): An International Perspective
Childhood-Onset Systemic Lupus Erythematosus (cSLE): An International Perspective
Childhood-onset systemic lupus erythematosus (cSLE) is a severe and potentially life-threatening chronic autoimmune diseas...
Cephalosporin Allergy: Updates on Diagnostic Testing
Cephalosporin Allergy: Updates on Diagnostic Testing
Cephalosporins are one of the most prescribed antibiotics worldwide and are implicated in a wide range of hypersensitivity...
Treatment of COVID-19 Associated Olfactory Dysfunction: A Systematic Review
Treatment of COVID-19 Associated Olfactory Dysfunction: A Systematic Review
COVID -19 associated olfactory dysfunction is widespread, yet effective treatment strategies remain unclear. This article ...
Getting in Shape: Updates in Exercise Anaphylaxis
Getting in Shape: Updates in Exercise Anaphylaxis
Exercise induced anaphylaxis (EIA) can be difficult to diagnose due to the interplay of co-factors on clinical presentatio...
Can Physicochemical Properties Alter the Potency of Aeroallergens? Part 1 – Aeroallergen Protein Families
Can Physicochemical Properties Alter the Potency of Aeroallergens? Part 1 – Aeroallergen Protein Families
Respiratory allergies are non-communicable diseases caused by the hypersensitivity of the immune system to environmental a...
Extent of Endoscopic Sinus Surgery in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
Extent of Endoscopic Sinus Surgery in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
There is an incomplete understanding regarding the extent of endoscopic sinus surgery (ESS) in managing chronic rhinosinus...
Mast Cells and Mas-related G Protein-coupled Receptor X2: Itching for Novel Pathophysiological Insights to Clinical Relevance
Mast Cells and Mas-related G Protein-coupled Receptor X2: Itching for Novel Pathophysiological Insights to Clinical Relevance
Clinical interest in non-IgE activation of mast cells has been growing since the description of the human MRGPRX2 receptor...
Olfactory Dysfunction in Chronic Rhinosinusitis with Nasal Polyps: Effect of Treatment with Emphasis on Biological Therapy
Olfactory Dysfunction in Chronic Rhinosinusitis with Nasal Polyps: Effect of Treatment with Emphasis on Biological Therapy
Olfactory dysfunction significantly impacts quality of life that affects a majority of the patients with chronic rhinosinu...
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe
Food allergies are immune-mediated, complex disorders, which are the source of increasing health concern worldwide. The go...
Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study)
Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study)
We aimed to reach an Italian multidisciplinary consensus on some crucial aspects of treatment decision making in CRSwNP, f...
Reversible Elevation of Tryptase Over the Individual's Baseline: Why is It the Best Biomarker for Severe Systemic Mast Cell Activation and MCAS?
Reversible Elevation of Tryptase Over the Individual's Baseline: Why is It the Best Biomarker for Severe Systemic Mast Cell Activation and MCAS?
Mast cell (MC) activation syndromes (MCAS) are conditions defined by recurrent episodes of severe systemic anaphylaxis or ...
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