Abdullah H, Heaney LG, Cosby SL, McGarvey LP (2014) Rhinovirus upregulates transient receptor potential channels in a human neuronal cell line: implications for respiratory virus-induced cough reflex sensitivity. Thorax 69:46–54

Article  PubMed  CAS  Google Scholar 

Alving K, Sundström C, Matran R, Panula P, Hökfelt T, Lundberg JM (1991) Association between histamine-containing mast cells and sensory nerves in the skin and airways of control and capsaicin-treated pigs. Cell Tissue Res 264:529–538

Article  PubMed  CAS  Google Scholar 

Anders S, Huber W (2010) Differential expression analysis for sequence count data. Genome Biol 11:R106

Article  PubMed  PubMed Central  CAS  Google Scholar 

Arizono N, Matsuda S, Hattori T, Kojima Y, Maeda T, Galli SJ (1990) Anatomical variation in mast cell nerve associations in the rat small intestine, heart, lung, and skin. Similarities of distances between neural processes and mast cells, eosinophils, or plasma cells in the jejunal lamina propria. Lab Invest 62:626–634

PubMed  CAS  Google Scholar 

Austah ON, Ruparel NB, Henry MA, Fajardo RJ, Schmitz JE, Diogenes A (2016) Capsaicin-sensitive innervation modulates the development of apical periodontitis. J Endod 42:1496–1502

Article  PubMed  Google Scholar 

Baral P, Udit S, Chiu IM (2019) Pain and immunity: implications for host defence. Nat Rev Immunol 19:433–447

Article  PubMed  PubMed Central  CAS  Google Scholar 

Barbara G, Stanghellini V, De Giorgio R, Cremon C, Cottrell GS, Santini D, Pasquinelli G, Morselli-Labate AM, Grady EF, Bunnett NW et al (2004) Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 126:693–702

Article  PubMed  Google Scholar 

Blaxter M, Mann J, Chapman T, Thomas F, Whitton C, Floyd R, Abebe E (2005) Defining operational taxonomic units using DNA barcode data. Philos Trans R Soc Lond B Biol Sci 360:1935–1943

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bowden JJ, Baluk P, Lefevre PM, Schoeb TR, Lindsey JR, McDonald DM (1996) Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways. Am J Physiol 270:L393-403

PubMed  CAS  Google Scholar 

Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP (2016) DADA2: high-resolution sample inference from Illumina amplicon data. Nat Methods 13:581–583

Article  PubMed  PubMed Central  CAS  Google Scholar 

Graham AC, Temple RM, Obar JJ (2015) Mast cells and influenza a virus: association with allergic responses and beyond. Front Immunol 6:238

Article  PubMed  PubMed Central  Google Scholar 

Hammond DL, Ruda MA (1991) Developmental alterations in nociceptive threshold, immunoreactive calcitonin gene-related peptide and substance P, and fluoride-resistant acid phosphatase in neonatally capsaicin-treated rats. J Comp Neurol 312:436–450

Article  PubMed  CAS  Google Scholar 

He Y, Li C, Wang Z, Yang Z, Wei J, Ren L, Deng Y, Chen S, Ye Z, Zang N et al (2022) C-fiber degeneration enhances alveolar macrophage-mediated IFN-α/β response to respiratory syncytial virus. Microbiol Spectr 10(6):e0241022

Hu D, Al-Shalan HAM, Shi Z, Wang P, Wu Y, Nicholls PK et al (2020) Distribution of nerve fibers and nerve-immune cell association in mouse spleen revealed by immunofluorescent staining. Sci Rep 10(1):9850

Article  PubMed  PubMed Central  CAS  Google Scholar 

Hu K (2020) Become competent within one day in generating boxplots and violin plots for a novice without prior R experience. Methods Protoc. https://doi.org/10.3390/mps3040064

Article  PubMed  PubMed Central  Google Scholar 

Hunsperger EA, Wilcox CL (2003) Capsaicin-induced reactivation of latent herpes simplex virus type 1 in sensory neurons in culture. J Gen Virol 84:1071–1078

Article  PubMed  CAS  Google Scholar 

Jancsó G (1978) Selective degeneration of chemosensitive primary sensory neurones induced by capsaicin: glial changes. Cell Tissue Res 195:145–152

Article  PubMed  Google Scholar 

Jancsó G, Kiraly E, Jancsó-Gábor A (1977) Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 270:741–743

Article  PubMed  Google Scholar 

Jeong E, Lee JY (2011) Intrinsic and extrinsic regulation of innate immune receptors. Yonsei Med J 52:379–392

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kihara N, de la Fuente SG, Fujino K, Takahashi T, Pappas TN, Mantyh CR (2003) Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats. Gut 52:713–719

Article  PubMed  PubMed Central  CAS  Google Scholar 

Kim YK, Shin JS, Nahm MH (2016) NOD-like receptors in infection, immunity, and diseases. Yonsei Med J 57:5–14

Article  PubMed  CAS  Google Scholar 

Kiuchi MG, Esler MD, Fink GD, Osborn JW, Banek CT, Böhm M, Denton KM, DiBona GF, Everett THt, Grassi Get al. (2019) Renal denervation update from the international sympathetic nervous system summit: JACC state-of-the-art review. J Am Coll Cardiol 73:3006–3017

Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S et al (2020) Gut-innervating nociceptor neurons regulate Peyer’s patch microfold cells and SFB levels to mediate salmonella host defense. Cell 180:33-49.e22

Article  PubMed  CAS  Google Scholar 

Lei C, Sun R, Xu G, Tan Y, Feng W, McClain CJ, Deng Z (2022) Enteric VIP-producing neurons maintain gut microbiota homeostasis through regulating epithelium fucosylation. Cell Host Microbe 30:1417-1434.e1418

Article  PubMed  PubMed Central  CAS  Google Scholar 

Marin V, Poulsen K, Odena G, McMullen MR, Altamirano J, Sancho-Bru P, Tiribelli C, Caballeria J, Rosso N, Bataller R et al (2017) Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients. J Hepatol 67:1018–1025

Article  PubMed  PubMed Central  CAS  Google Scholar 

Martinez-Sanchez N, Sweeney O, Sidarta-Oliveira D, Caron A, Stanley SA, Domingos AI (2022) The sympathetic nervous system in the 21st century: neuroimmune interactions in metabolic homeostasis and obesity. Neuron 110:3597–3626

Article  PubMed  PubMed Central  CAS  Google Scholar 

McGlone F, Wessberg J, Olausson H (2014) Discriminative and affective touch: sensing and feeling. Neuron 82:737–755

Article  PubMed  CAS  Google Scholar 

McMahon SB, La Russa F, Bennett DL (2015) Crosstalk between the nociceptive and immune systems in host defence and disease. Nat Rev Neurosci 16:389–402

Article  PubMed  CAS  Google Scholar 

Middleton SJ, Barry AM, Comini M, Li Y, Ray PR, Shiers S, Themistocleous AC, Uhelski ML, Yang X, Dougherty PM et al (2021) Studying human nociceptors: from fundamentals to clinic. Brain 144:1312–1335

Article  PubMed  PubMed Central  Google Scholar 

Naukkarinen A, Järvikallio A, Lakkakorpi J, Harvima IT, Harvima RJ, Horsmanheimo M (1996) Quantitative histochemical analysis of mast cells and sensory nerves in psoriatic skin. J Pathol 180:200–205

Article  PubMed  CAS  Google Scholar 

Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA (2015) Robust enumeration of cell subsets from tissue expression profiles. Nat Methods 12:453–457

Article  PubMed  PubMed Central  CAS  Google Scholar 

Omar S, Clarke R, Abdullah H, Brady C, Corry J, Winter H, Touzelet O, Power UF, Lundy F, McGarvey LP et al (2017) Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells. PLoS ONE 12:e0171681