Abeysinghe A, Deshapriya R, Udawatte C (2020) Alzheimer’s disease; a review of the pathophysiological basis and therapeutic interventions. Life Sci 256:117996. https://doi.org/10.1016/j.lfs.2020.117996
Article PubMed CAS Google Scholar
Abiria SA, Colbran RJ (2010) CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation. J Neurochem 112(1):150–161. https://doi.org/10.1111/j.1471-4159.2009.06436.x
Article PubMed CAS Google Scholar
Alshial EE, Abdulghaney MI, Wadan AS et al (2023) Mitochondrial dysfunction and neurological disorders: a narrative review and treatment overview. Life Sci 334:122257. https://doi.org/10.1016/j.lfs.2023.122257
Article PubMed CAS Google Scholar
Ames JB (2021) L-type Ca(2+) channel regulation by calmodulin and CaBP1. Biomolecules. https://doi.org/10.3390/biom11121811
Article PubMed PubMed Central Google Scholar
Andersen JV, Markussen KH, Jakobsen E et al (2021) Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration. Neuropharmacology 196:108719. https://doi.org/10.1016/j.neuropharm.2021.108719
Article PubMed CAS Google Scholar
Aravind P, Bulbule SR, Hemalatha N, Babu RL, Devaraju KS (2021) Elevation of gene expression of calcineurin, calmodulin and calsyntenin in oxidative stress induced PC12 cells. Genes Dis 8(1):87–93. https://doi.org/10.1016/j.gendis.2019.09.001
Article PubMed CAS Google Scholar
Arbel-Ornath M, Hudry E, Boivin JR et al (2017) Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain. Mol Neurodegener 12(1):27. https://doi.org/10.1186/s13024-017-0169-9
Article PubMed PubMed Central CAS Google Scholar
Arboleda-Velasquez JF, Lopera F, O’Hare M et al (2019) Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report. Nat Med 25(11):1680–1683. https://doi.org/10.1038/s41591-019-0611-3
Article PubMed PubMed Central CAS Google Scholar
Arispe N, Rojas E, Pollard HB (1993) Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc Natl Acad Sci USA 90(2):567–571. https://doi.org/10.1073/pnas.90.2.567
Article PubMed PubMed Central CAS Google Scholar
Azargoonjahromi A (2024) The duality of amyloid-β: its role in normal and Alzheimer’s disease states. Mol Brain 17(1):44. https://doi.org/10.1186/s13041-024-01118-1
Article PubMed PubMed Central CAS Google Scholar
Bai R, Guo J, Ye XY, Xie Y, Xie T (2022) Oxidative stress: the core pathogenesis and mechanism of Alzheimer’s disease. Ageing Res Rev 77:101619. https://doi.org/10.1016/j.arr.2022.101619
Article PubMed CAS Google Scholar
Baltaci SB, Mogulkoc R, Baltaci AK (2019) Molecular mechanisms of early and late LTP. Neurochem Res 44(2):281–296. https://doi.org/10.1007/s11064-018-2695-4
Article PubMed CAS Google Scholar
Baracaldo-Santamaría D, Avendaño-Lopez SS, Ariza-Salamanca DF et al (2023) Role of calcium modulation in the pathophysiology and treatment of Alzheimer’s disease. Int J Mol Sci. https://doi.org/10.3390/ijms24109067
Article PubMed PubMed Central Google Scholar
Barcomb K, Hell JW, Benke TA, Bayer KU (2016) The CaMKII/GluN2B protein interaction maintains synaptic strength. J Biol Chem 291(31):16082–16089. https://doi.org/10.1074/jbc.M116.734822
Article PubMed PubMed Central CAS Google Scholar
Bartus RT, Dean RL 3rd, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217(4558):408–414. https://doi.org/10.1126/science.7046051
Article PubMed CAS Google Scholar
Bayer KU, De Koninck P, Leonard AS, Hell JW, Schulman H (2001) Interaction with the NMDA receptor locks CaMKII in an active conformation. Nature 411(6839):801–805. https://doi.org/10.1038/35081080
Article PubMed CAS Google Scholar
Beauverger P, Ozoux ML, Bégis G et al (2020) Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy. Cardiovasc Res 116(2):329–338. https://doi.org/10.1093/cvr/cvz097
Article PubMed CAS Google Scholar
Beckendorf J, van den Hoogenhof MMG, Backs J (2018) Physiological and unappreciated roles of CaMKII in the heart. Basic Res Cardiol 113(4):29. https://doi.org/10.1007/s00395-018-0688-8
Article PubMed PubMed Central CAS Google Scholar
Beghi S, Cavaliere F, Buschini A (2020) Gene polymorphisms in calcium-calmodulin pathway: focus on cardiovascular disease. Mutat Res Rev Mutat Res 786:108325. https://doi.org/10.1016/j.mrrev.2020.108325
Article PubMed CAS Google Scholar
Beghi S, Furmanik M, Jaminon A et al (2022) Calcium signalling in heart and vessels: role of calmodulin and downstream calmodulin-dependent protein kinases. Int J Mol Sci. https://doi.org/10.3390/ijms232416139
Article PubMed PubMed Central Google Scholar
Bekdash RA (2021) The cholinergic system, the adrenergic system and the neuropathology of Alzheimer’s disease. Int J Mol Sci. https://doi.org/10.3390/ijms22031273
Article PubMed PubMed Central Google Scholar
Békés M, Langley DR, Crews CM (2022) Protac targeted protein degraders: the past is prologue. Nat Rev Drug Discov 21(3):181–200. https://doi.org/10.1038/s41573-021-00371-6
Article PubMed PubMed Central CAS Google Scholar
Belder CRS, Schott JM, Fox NC (2023) Preparing for disease-modifying therapies in Alzheimer’s disease. Lancet Neurol 22(9):782–783. https://doi.org/10.1016/s1474-4422(23)00274-0
Berry AS, Harrison TM (2023) New perspectives on the basal forebrain cholinergic system in Alzheimer’s disease. Neurosci Biobehav Rev 150:105192. https://doi.org/10.1016/j.neubiorev.2023.105192
Article PubMed PubMed Central CAS Google Scholar
Bhattacharyya M, Karandur D, Kuriyan J (2020a) Structural insights into the regulation of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII). Cold Spring Harb Perspect Biol. https://doi.org/10.1101/cshperspect.a035147
Article PubMed PubMed Central Google Scholar
Bhattacharyya M, Lee YK, Muratcioglu S et al (2020b) Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation. Elife. https://doi.org/10.7554/eLife.53670
Article PubMed PubMed Central Google Scholar
Blumenfeld J, Yip O, Kim MJ, Huang Y (2024) Cell type-specific roles of APOE4 in Alzheimer disease. Nat Rev Neurosci 25(2):91–110. https://doi.org/10.1038/s41583-023-00776-9
Article PubMed PubMed Central CAS Google Scholar
Bohush A, Leśniak W, Weis S, Filipek A (2021) Calmodulin and its binding proteins in Parkinson’s disease. Int J Mol Sci. https://doi.org/10.3390/ijms22063016
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