aUniversity Milano-Bicocca, Milan, Italy

bStatistical Consultant, Ingelheim am Rhein

cUniversitätsklinikum des Saarlandes, Homburg, Germany

dPopulation Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada

eDepartment of Medicine, INCLIVA Research Institute, University of Valencia, Valencia, Spain

Correspondence to Prof. Giuseppe Mancia, University of Milano-Bicocca, Piazza dei Daini 4, 20126 Milano, Italy. Tel: +39 3474327142; e-mail: [email protected]

Abbreviations: ACE, angiotensin converting enzyme; BP, blood pressure; HR, heart rate; S, systolic; SBP-CV, systolic blood pressure-coefficient of variation; SD, standard deviations

Received 6 January, 2024

Revised 21 April, 2024

Accepted 21 April, 2024

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